Cannabis resin now 25% more potent, global study reveals

Concentrations of intoxicating THC have risen, data from more than 80,000 street drug samples gathered over 50 years shows

Cannabis resin – or “hash” – has increased in strength by nearly 25% over the past half century, a major international study has revealed.

Researchers with the Addiction and Mental Health Group at the University of Bath analysed data from more than 80,000 cannabis street samples tested in the past 50 years in the US, UK, Netherlands, France, Denmark, Italy and New Zealand.

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I feel bullied and hopeless. How can I find happiness? | Dear Mariella

Go back to therapy and use the skills to better understand yourself and combat self loathing, says Mariella Frostrup

The dilemma I am a woman in my 30s. On paper I am bright – an Oxford graduate with a slew of prestigious qualifications, extracurricular achievements and a fairly successful career. The reality is I just feel pathetic, ignorant and gormless. I’ve got to where I am because I’m adept at analysing and memorising information, while clearly lacking other types of intelligence. I was bullied in school and continue to be bullied in adult life, which to me reinforces how pathetic I am.

I am very physically and socially clumsy, can’t understand body language, have trouble processing what people are saying and take things literally. This has led people to comment that I am autistic. I have never sought a formal diagnosis because I do not want to use it as an excuse or even a weapon, which I’ve seen other autistic women do.

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Viral video of ballerina with Alzheimer’s shows vital role of music in memory

Music’s primal power for those living with dementia has inspired thousands of YouTube views for a clip of a former dancer

We see a frail and elderly woman in a chair, her eyes downcast. She motions for the music to be turned up, a swelling melody from Tchaikovsky’s Swan Lake, and with a little encouragement her hands begin to flutter. Then suddenly her eyes flash and she’s Odette the swan queen at the misty lakeside, arms raised. She leans forward, wrists crossed in classic swan pose; her chin lifts as if she’s commanding the stage once more, her face lost in reverie.

The woman in the film is Marta Cinta González Saldaña, a former ballet dancer who died in 2019, the year the video was shot. But the clip has gone viral since being posted recently by Spanish organisation Música Para Despertar (Music to Awaken), which promotes the value of music for those living with Alzheimer’s. Many of the details accompanying the video on its journey around the internet have been erroneous. Marta Cinta was not a member of the “New York Ballet” (there’s no such company) or the actual New York City Ballet, but seems to have run her own dance company in the city; the ballerina performing in the intercut video is not her but Ulyana Lopatkina, who is not even dancing Swan Lake but Mikhail Fokine’s The Dying Swan. Yet none of that takes away the impact of watching someone seemingly light up and have their memories unlocked by the power of melody. It’s as if you’re seeing Saldaña inhabit her true self.

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Measles cases hit 20-year high as Covid disrupts vaccinations, report finds

Number of people dying from the disease also increased by 50% since 2016, according to data from the WHO and CDC

The number of measles cases worldwide surged to nearly 900,000 in 2019, the highest figure in more than two decades, underlining a significant U-turn in global progress to combat the disease.

Data from the World Health Organization (WHO) and US Centers for Disease Control and Prevention (CDC) found that the number of people dying from measles also increased by 50% since 2016, with an estimated 207,500 deaths in 2019 alone.

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Scientist behind BioNTech/Pfizer vaccine says it can end pandemic

Exclusive: BioNTech’s CEO Uğur Şahin says he is confident vaccine can ‘bash the virus over the head’

The scientist behind the first Covid-19 vaccine to clear interim clinical trials says he is confident his product can “bash the virus over the head” and put an end to the pandemic that has held the world hostage in 2020.

The German company BioNTech and the US pharmaceutical giant Pfizer announced via a press release on Monday that their jointly developed vaccine candidate had outperformed expectations in the crucial phase 3 trials, proving 90% effective in stopping people from falling ill.

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Alcoholic anaesthetist jailed for killing Briton during caesarean birth in France

Helga Wauters imprisoned for three years and banned from practising after death of Xynthia Hawke

An alcoholic anaesthetist who botched an emergency caesarean operation leaving a young British mother dead has been sentenced to three years in prison and banned from practising medicine.

Helga Wauters, 51, was found guilty of manslaughter after pushing a breathing tube into 28-year-old Xynthia Hawke’s oesophagus instead of her windpipe. Even after Hawke cried out in pain, vomited, turned blue and went into cardiac arrest, the anaesthetist, who admitted she had an alcohol problem and had been drinking since early morning on the day of the operation, failed to react.

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Spike in yellow fever deaths prompts Nigeria to revive vaccination campaigns

Resurgence of disease linked to factors including climate crisis and focus of health resources on Covid response

More than 70 people are feared to have died of yellow fever in Nigeria since September, as health authorities warn of a resurgence of the disease.

The country recorded 47 deaths from yellow fever throughout the whole of 2019.

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Totnes Covid concerns reflect UK-wide rise in conspiracy theories

Suspicion in Devon town of face masks and 5G means take-up of vaccine may face resistance

Like many people living in or around Totnes in Devon, David, who is in his 70s, has his own theories about coronavirus and its origins. Sitting in the armchair of his house, he says the pandemic is a secret plot to impose a totalitarian world government and a nefarious effort to crush freedom. He scrolls through Facebook, which he recently signed up to, to show many with similar beliefs.

David came to many of these ideas recently. When the pandemic hit, he started looking for answers. “I’m friends with a few people who are active in researching what is going on. I quickly made contact with others putting posts on the internet.”

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‘She made music jump into 3D’: Wendy Carlos, the reclusive synth genius

She went platinum by plugging Bach into 20th-century machines, and was soon working with Stanley Kubrick. But prejudice around her gender transition pushed Wendy Carlos out of sight

This summer, an 80-year-old synthesiser pioneer suddenly appeared online. She had been silent for 11 years, but now something had appeared that she just wouldn’t tolerate. “Please be aware there’s a purported ‘biography’ on me just released,” wrote Wendy Carlos on the homepage of her 16-bit-friendly website, a Siamese cat and a synthesiser behind her portrait. “No one ever interviewed me [for it], nor anyone I know,” she went on. “Aren’t there new, more interesting targets?”

Given that Carlos is arguably the most important living figure in the history of electronic music, it’s remarkable that Amanda Sewell’s Wendy Carlos: A Biography is the first book about her. This is the musician who pushed Robert Moog to perfect his first analogue synthesiser, from which pop, prog, electronica and film music flourished. Her smash-hit 1968 album Switched-On Bach made the Moog internationally famous and became the second classical album ever to go platinum in the US. Then came her extraordinary soundtracks for A Clockwork Orange, The Shining and Tron. She made an ambient album five years before Brian Eno did, and jumped from analogue machines to do leading work in digital synthesis, but worried that her status as one of the first visible transgender artists in the US would overshadow it.

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Siena Castellon: ‘Autistic people are really struggling with how uncertain things are’

The 18-year-old autism campaigner and international children’s peace prize finalist on why diagnosis of the condition for girls urgently needs improving

Each morning Siena Castellon synchronises her morning routine to music with the same 30-minute playlist. Different songs act as time markers. “The trick is to choose music you love and to listen to the same playlist every day,” explains the teenager.

When Wonderwall by Oasis comes on she knows she should be brushing her teeth. By the time Summertime Sadness by Lana Del Rey is playing she is walking out the door.

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Joan Armatrading: ‘I want to make a heavy metal album – with lots of guitar shredding’

At the age of seven, she flew to Birmingham from Antigua on her own – and became the first globally successful British female singer-songwriter. As she wins the award she once gave to Margaret Thatcher, Joan Armatrading looks back

‘It’s very nice to be honoured,” says Joan Armatrading, down the phone from her home in Surrey. The 69-year-old is talking about receiving this year’s Women of the Year lifetime achievement award, which sees her honoured alongside the likes of child burns survivor Sylvia Mac and Adwoa Dickson, who set up a community choir for young women who survived trafficking. “Whether I measure up is another question.”

She’s joking, of course, but what does the continued existence of the award tell us about where the struggle for equality is in 2020? “It’s maybe not as relevant as it was in 1955,” she says, “when Tony Lothian set it up after being denied admission to a men-only meeting. But women are still doing incredible things in this society, so reward them.”

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Lessons via loudspeaker: the students studying across India’s digital divide

How do you learn from home without a laptop? Teachers are getting creative, but the pandemic remains a vast challenge

Vemula Deena lives in one of the tin huts strung along a narrow lane in the heart of Vijayawada, the business capital of Andhra Pradesh, in the south-east of India. Her parents are construction labourers. Vemula is 13 and wants to be a politician, enamoured of the spotless white kurta-pyjamas they wear and their public speaking.

But her school has closed its doors in the face of the Covid pandemic and gone online, effectively shutting her out. Vemula continues to practise her oration as she does her household chores.

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‘We have lost a limb’: Azu Nwagbogu, the visionary curator bringing African art home

From helping photographers capture the Nigerian protests to exhibiting during a pandemic, the director of LagosPhoto festival has had his work cut out. Now he wants to fight ‘afro-pessimism’ and the posturing around Black Lives Matter

When I first spoke to Azu Nwagbogu, the recent protests against police brutality in his native Nigeria had just entered their second week. The curator was upbeat, describing them as “an incredible awakening”. A week later, when we made contact again, he sounded more sombre, but no less defiant, following the fatal police shootings of at least 12 protesters at the Lekki toll gate in Lagos, the main gathering point for the daily demonstrations.

“This protest is not about ‘the poor masses’,” he tells me. “My sister, who is a medical doctor and a consultant anaesthetist, was active in the protests. Everyone who isn’t in government has had enough. The genie has been let out of the bottle and it won’t go back in without the wishes of the people being fulfilled.”

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From schoolboy to tea seller: Covid poverty forces India’s children into work

The pandemic has pushed millions of urban poor into crisis – and left children struggling to help their families survive

Subhan Shaikh used to start the day with a cup of cinnamon-flavoured tea, brought to him by his mother, Sitara, before he got ready for school. But the lockdown in March brought her salary as a school bus attendant to an end, and providing food – never mind tea – for Subhan, 14, and his two younger sisters, became a challenge.

Today, life for Subhan revolves around tea, which has become a lifeline for his family. After seeing his mother struggle, Subhan decided to do something and became a tea seller on the streets of Mumbai.

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‘I just want to see the person I always saw in my head’: the story of a face

How a trans woman found the surgery that could restore her sense of self

When the children at Sophia Drake’s primary school in rural Wales used to talk about what superpower they’d like, she always told them she wanted to be a shapeshifter. “But I didn’t want to be an animal. I didn’t want to be Spider-Man or Muhammad Ali, I just wanted to change into a woman.”

Drake was born biologically male. For as long as she can remember, she felt different and uncomfortable, and experimented with whatever identities and fads she could in an effort to belong. Video games saved her. When she discovered them as a child, she found she could get lost in a world where she could embody any character she liked. “They took me to places where I didn’t have all those issues and problems; I wasn’t this confused child, I could pick who I wanted to be,” she told me.

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Nearly one in five Covid patients later diagnosed with mental illness – study

US data shows nearly twice as many diagnoses over three months among those testing positive

Nearly one in five people who have had Covid-19 are diagnosed with a psychiatric disorder such as anxiety, depression or insomnia within three months of testing positive for the virus, according to a study that suggests action is needed to mitigate the mental health toll of the pandemic.

The analysis – conducted by researchers from the University of Oxford and NIHR Oxford Health Biomedical Research Centre – also found that people with a pre-existing mental health diagnosis were 65% more likely to be diagnosed with Covid-19 than those without, even accounting for known risk factors such as age, sex, race, and underlying physical conditions.

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‘Very early days’: Johnson says UK cannot yet rely on Covid vaccine – video

Boris Johnson has welcomed the promising news about the BioNTech/Pfizer coronavirus vaccine and said the UK was at 'the front of the pack' if and when it becomes available. At a Downing Street briefing, however, the prime minister also cautioned that it was 'very early days'. He said the vaccine still needed to be peer reviewed and clear any potential safety hurdles. 'We cannot rely on this news as a solution,' he said. 'The biggest mistake we could make now would be to slacken our resolve at a critical moment'

UK rollout of Covid vaccine could start before Christmas

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Hopes rise for end of pandemic as Pfizer says vaccine is 90% effective

Global stocks surge and experts optimistic as Covid vaccine exceeds expectations

Hopes are soaring that a Covid vaccine is within reach, following news that an interim analysis has shown Pfizer/BioNTech’s candidate was 90% effective in protecting people from transmission of the virus in global trials.

The vaccine performed much better than most experts had hoped for, according to the companies’ analysis, and brings into view a potential end to a pandemic that has killed more than a million people, battered economies and upended daily life worldwide.

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Pfizer/BioNTech vaccine announcement is cause for cautious celebration

Interim trial results are encouraging as scientists welcome news

It is not yet the end of the pandemic, but the announcement by Pfizer/BioNTech that their vaccine has been 90% successful in the vital large-scale trials has got even the soberest of scientists excited.

These are interim results and the trial will continue into December to collect more data. The two companies – a tiny German biotech with the big idea and the giant pharma company Pfizer with the means to develop it – have not yet published their detailed data, so it is all on trust. And yet, nobody is suggesting the results have been over-egged. It looks as though the vaccine not only works, but works better than anyone hoped.

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Armed groups target Colombia’s children as reform process slows

For families in province of Cauca, time is running out as drug gangs and guerrilla groups exploit Covid chaos


Luis Troches was walking home from the shop in late July when armed men stopped him along a dirt road in south-west Colombia. They gave the 14-year-old an ultimatum: he could join their group – dissidents from the demobilised Revolutionary Armed Forces of Colombia (Farc) – or they could take him and his 11-year-old sister by force.

“He came home scared and distant,” said his mother, Luzmery. Both knew that the men, who control their hamlet in the north of Cauca province, would be back for an answer. “He told me, ‘I don’t want to go. What should I do?’”

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