Rising temperatures causing distress to foetuses, study reveals

Climate crisis increases risks for subsistence farmers in Africa who usually work throughout pregnancy

Rising temperatures driven by climate breakdown are causing distress to the foetuses of pregnant farmers, who are among the worst affected by global heating.

A study revealed that the foetuses of women working in fields in the Gambia showed concerning rises in heart rates and reductions in the blood flow to the placenta as conditions became hotter. The women, who do much of the agricultural labour and work throughout pregnancy, told the scientists that temperatures had noticeably increased in the past decade.

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Concussion and head trauma in contact sports to be examined by parliamentary inquiry, Greens say

Lidia Thorpe says Labor and Coalition back hearings while ‘sports organisations need to be transparent about evidence that informs concussion policies’

A federal parliamentary committee will examine concussion and repeated head trauma in contact sports, with the Greens saying they have the support of Labor and the Coalition to establish the inquiry.

The push follows growing concern about chronic traumatic encephalopathy, or CTE, the neurodegenerative disease associated with repeated head trauma and concussion that has been increasingly linked to contact and collision sports.

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Plant-based diet can cut bowel cancer risk in men by 22%, says study

Researchers find no such link for women, suggesting connection between diet and bowel cancer is clearer for men

Eating a plant-based diet rich in vegetables, whole grains, nuts and legumes can reduce the risk of bowel cancer in men by more than a fifth, according to research.

A large study that involved 79,952 US-based men found that those who ate the largest amounts of healthy plant-based foods had a 22% lower risk of bowel cancer compared with those who ate the least.

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Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows

Researchers say despite the lack of symptom relief, more trials are needed to focus on the targeted use of medicinal cannabis

The first high quality study looking at the impact of cannabidiol oil on palliative care patients with advanced cancer found it did not improve their pain, depression, anxiety, or quality of life.

Palliative care is one of the conditions for which medicinal cannabis has been approved in Australia.

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Covid blood-thinner drug treatment dangerous and does not work – study

UK government-backed Heal-Covid trial finds Apixaban can cause dangerous bleeding and does not improve prognosis

A blood-thinning drug given as a potential life-saver to many patients recovering from severe Covid does not work and can cause major bleeding, research shows.

The findings have led to calls for doctors to stop advising people to take Apixaban, because it does not stop them from dying or ending up back in hospital and also can have serious side-effects.

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UK breakthrough on lung cancer helps target patients at risk of relapse

Research programme buys doctors crucial time by spotting returning tumours before symptoms appear

Seven years ago, Kelly Harrop was working at a stables while also running regularly in half marathons and 10k races. Then she began to suffer digestive problems. Scans eventually revealed marks on her lungs. The subsequent diagnosis was direct. “I had lung cancer. It was a shock. I was fit, healthy and had never smoked,” she told the Observer.

Kelly had surgery to remove the tumour, followed by chemotherapy. But doctors knew there was a risk of the tumour reappearing, so they enrolled her in a new research programme, TRACERx. Funded by Cancer Research UK, the £14m project was set up 10 years ago to investigate how lung tumours arise and evolve. A total of 850 patients with early-stage lung cancer were studied and followed from diagnosis to treatment.

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Australia gives world-first approval for faecal transplants to restore gut health

BiomeBank in Adelaide collects healthy genetic material from the microbiomes of donors to treat potentially deadly bacterial condition

Australia has given regulatory approval for faecal transplants, the first country in the world to do so.

For such a transplant, poo donors – who have to meet a list of conditions – provide healthy genetic material from their microbiomes. The microbes are collected and delivered into the gastrointestinal tract of an unhealthy person, where they have been shown to treat conditions such as the potentially deadly bacteria Clostridium difficile colitis (C diff).

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Invasive mosquito could disrupt Africa’s ‘landscape of malaria’ after cases rise

Insecticide-resistant newcomer caused unprecedented urban outbreak in Ethiopia and can survive the dry season, scientists say

Scientists are warning that the invasion of an insecticide-resistant mosquito could change Africa’s “landscape of malaria” after research showed it caused an unprecedented urban outbreak in Ethiopia.

An investigation into a steep rise in cases in the Ethiopian city of Dire Dawa during a dry season this year identified the mosquito as the cause of the outbreak. Scientists say it is the strongest evidence to date that it could prompt surges of malaria in areas typically less affected by the disease.

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Floods and warm weather perfect storm for Japanese encephalitis outbreak in Australia, researchers warn

Modellers say those within 4km of an infected piggery potentially vulnerable, meaning 740,546 people at risk of mosquito-borne virus

Warming temperatures combined with flood waters could leave almost 750,000 Australians vulnerable to Japanese encephalitis – a disease that until last year was confined to Asia and far-northern Australia.

The mosquito-borne disease was first detected on the Australian mainland in 1998, but its range expanded dramatically earlier this year. Cases were reported in dozens of southern piggeries (pigs are one of the main carriers of the virus) and there were also 31 confirmed cases in humans and six deaths.

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Common drugs could fight obesity and diabetes, say scientists

Researchers identify medications that could be repurposed, including treatments for heart conditions and stomach ulcers

Scientists have pinpointed a range of commonly used medicines that could be repurposed to treat people suffering from obesity and diabetes.

The medicines – to be outlined at the International Congress on Obesity in Melbourne this weekend – include treatments for stomach ulcers and heart rhythm disorders and were identified using sophisticated computer programs.

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Covid: one in 50 thought to be infected in England, data shows

Based on results from random swabbing, ONS says 1.1 million people in country have virus

Covid infection levels are continuing to rise in England, with more than 1.1 million people thought to have had the virus in the most recent week, data has revealed.

According to figures from the Office for National Statistics, based on swabs from randomly selected households, about one in 50 people in England – 2% of the population – had Covid in the week ending 24 September, an increase from one in 65 the week before.

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Children of mothers who eat junk food more likely to be overweight – study

Higher obesity risk linked to maternal diet of ultra-processed food is not affected by other lifestyle factors, US researchers say

Children of mothers who consume ultra-processed foods such as ready meals, sugary cereals and biscuits are more likely to grow up overweight or obese, a study suggests.

The link between a mother’s diet and her child’s obesity risk is independent of other lifestyle risk factors, including the child’s own consumption of ultra-processed food, according to the research. The findings are published in the BMJ.

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People with recent dementia diagnosis found to have higher suicide risk

Calls for more support after England research shows those diagnosed under 65 also at greater risk

People who have recently been diagnosed with dementia, or who are diagnosed with the condition at a younger age, are among those at increased risk of suicide, researchers have found. The findings have prompted calls for greater support for those experiencing such cognitive decline.

While previous research has explored a potential link between dementia diagnosis and suicide risk, the results have been inconclusive, with some suggesting a raised risk and others a reduced risk.

•In the UK and Ireland, Samaritans can be contacted on freephone 116 123, or email jo@samaritans.org or jo@samaritans.ie. In the US, the National Suicide Prevention Lifeline is at 800-273-8255 or chat for support. You can also text HOME to 741741 to connect with a crisis text line counselor. In Australia, the crisis support service Lifeline is 13 11 14. Other international helplines can be found at befrienders.org

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Obesity-related cancer rates nearly quadruple in Australia over three and a half decades

Researchers call on governments to implement national obesity strategy to help stem further rises in preventable cancers

The rate of obesity-related cancers in Australia has almost quadrupled in a few generations, new research suggests.

Researchers at the Daffodil Centre, a joint venture of Cancer Council New South Wales and the University of Sydney, analysed the rate of 10 obesity-linked cancers between 1983 and 2017.

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Anger at plans to roll back Covid vaccines to under-11s in England

Children aged 5-11 will no longer be offered Covid jabs, except those in clinical risk groups, UKHSA confirms

The decision to reduce the number of children who are offered Covid jabs has prompted outcry from parent groups and academics.

According to the UK Health Security Agency (UKHSA), children who had not turned five by the end of last month will not be offered a vaccination. The agency said the offer of Covid jabs to healthy 5-11-year-olds was always going to be temporary.

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Revealed: black and Asian people wait longer for cancer diagnosis in England than white people

Exclusive: Analysis of 126,000 cases over a decade shows ‘deeply worrying’ racial disparities in NHS wait times

Black and Asian people in England have to wait longer for a cancer diagnosis than white people, with some forced to wait an extra six weeks, according to a “disturbing” analysis of NHS waiting times.

A damning review of the world’s largest primary care database by the University of Exeter and the Guardian discovered minority ethnic patients wait longer than white patients in six of seven cancers studied. Race and health leaders have called the results “deeply concerning” and “absolutely unacceptable”.

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Fears over China’s access to genetic data of UK citizens

Biobank urged to review transfer of information for medical research

Rising political and security tensions between Beijing and the west have prompted calls for a review of the transfer of genetic data to China from a biomedical database containing the DNA of half a million UK citizens.

The UK Biobank said it had about 300 projects under which researchers in China were accessing “detailed genetic information” or other health data on volunteers.

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New ‘Parp inhibitors’ could prevent certain tumours appearing

Breakthrough research could see some genetic cancers neutralised before they take hold and is already being used for people at risk

Sue Hayward was first diagnosed with ovarian cancer in 2017. Doctors acted swiftly and she was given a hysterectomy followed by sessions of chemotherapy.

But her cancer returned within a year. “I carry a mutated version of a gene known as BRCA1 which makes me susceptible to breast and ovarian cancers,” said Hayward, who works at the John Radcliffe Hospital, Oxford. “It runs in families. My mother died of cancer and we assume her mother did as well.”

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Half of people with possible signs of cancer wait six months to contact a GP

Survey by Cancer Research UK shows poorer people less likely to see their family GP, reducing survival chances

Half of people with possible cancer symptoms in the UK do not contact a GP for at least six months, potentially reducing their chances of survival, research has found.

Poorer people are less likely than the better-off to see their family doctor once they have eventually sought medical help, a survey by Cancer Research UK found.

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Research on ‘molecular drills’ of skin cancer cells offers hope for treatment

Institute of Cancer Research in London isolates gene that allows tumours to spread through the body

Skin cancer cells produce “molecular drills” to penetrate healthy tissues and spread around the body, according to research that raises the prospect of new therapies for the disease.

Researchers used robotic microscopy to capture the formation of the drills by melanoma cells that were being grown in 3D skin-like material in the laboratory.

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