Charities say deaths will be prevented if ‘sponge on a string’ test is widely adopted
A test that can detect oesophageal cancer at an earlier stage than current methods should be made more widely available to prevent deaths, charities have said.
The capsule sponge test, previously known as Cytosponge, involves a patient swallowing a dissolvable pill on a string. The pill then releases a sponge which collects cells from the oesophagus as it is retrieved.
Continue reading...Exclusive: Pet owners risk contaminating their hands with neurotoxins for at least 28 days after application, scientists find
Vets should limit the use of flea treatments containing pesticides on dogs and cats, scientists have said, after a study revealed the vast amount of toxic substances in them that end up in rivers.
Pet owners using these flea treatments risk contaminating their hands with fipronil and imidacloprid, two insecticides, for at least 28 days after the treatment has been applied, according to research by the University of Sussex and Imperial College London.
Continue reading...Increase in cardiorespiratory levels of 3% annually found to be beneficial, Swedish research suggests
Men can reduce their risk of prostate cancer by as much as 35% by doing a little more jogging, cycling or swimming, a study suggests.
Boosting cardiorespiratory fitness by only 3% over the course of a year was linked to a much lower chance of developing the disease. The findings prompted the researchers to encourage men to boost their fitness levels to help cut their prostate cancer risk.
Continue reading...Inexpensive test can help diagnose even ‘inaccessible’ tumours earlier, speeding up treatment and improving outcomes
Surgeons and scientists have developed a world-first blood test for brain cancer that experts say could revolutionise diagnosis, speed up treatment and boost survival rates.
For years, brain tumours have remained notoriously difficult to diagnose. They affect hundreds of thousands of people worldwide each year, and kill more children and adults under the age of 40 in the UK than any other cancer.
Continue reading...As Buruli ulcer cases rise in Victoria, Australian researchers say they have finally solved the ‘transmission enigma’
When Alice Mika was bitten by a mosquito last summer in Melbourne’s west, she didn’t think anything of it.
Then, a small raised bump appeared on her ankle more than five months later and wouldn’t go away. She saw her GP who prescribed antibiotics, believing it to be a spider bite.
Continue reading...Surgeons at University of Pennsylvania attached modified organ from pig to brain-dead human body
Surgeons externally attached a pig liver to a brain-dead human body and watched it successfully filter blood, a step toward eventually trying the technique in patients with liver failure.
The University of Pennsylvania announced the novel experiment on Thursday, a different spin on animal-to-human organ transplants. In this case, the pig liver was used outside the donated body, not inside – a way to create a “bridge” to support failing livers by doing the organ’s blood-cleansing work externally, much like dialysis for failing kidneys.
Continue reading...Bone strength is set in childhood so better park access could prevent fractures in older people, study finds
Children with more green space near their homes have significantly stronger bones, a study has found, potentially leading to lifelong health benefits.
Scientists found that the children living in places with 20-25% more natural areas had increased bone strength that was equivalent to half a year’s natural growth.
Continue reading...US biotech firm designs cheaper, less invasive multi-cancer screening test it says could be ‘gamechanger’
Scientists have developed a simple DNA test that can identify 18 early-stage cancers that experts say could represent a medical “gamechanger”.
Cancer accounts for one in every six deaths worldwide, but early detection can significantly improve outcomes. Existing screening tests have drawbacks, including invasiveness, cost and low levels of accuracy for early stage disease.
Continue reading...Despite a surplus of eggs at fertility clinics around the country, very few end up being donated to research or other prospective parents
The vast majority of eggs frozen by prospective mothers go unused, causing headaches for IVF clinics and preventing potentially groundbreaking research.
Scientists are decrying a wasted opportunity as thousands of frozen eggs sit unused in storage instead of being used in potentially valuable medical research.
Continue reading...Extending the limit could help uncover causes of recurrent miscarriage and congenital conditions, experts say
Scientists are calling for a review of the 14-day rule on embryo research, saying that extending the limit could help uncover the causes of recurrent miscarriage and congenital conditions.
Until now, scientists studying the earliest stages of life have been restricted to cultivating embryos up to the equivalent of 14 days of development. They can then pick up the path of development several weeks later, on pregnancy scans and from material donated from terminations.
Continue reading...Gracell Biotechnologies acquisition marks China’s growing importance to the Anglo-Swedish drugmaker
AstraZeneca has struck a deal to buy a Chinese cancer therapy company for up to $1.2bn (£950m), as Britain’s biggest drugmaker expands its footprint in its second-largest market.
The Anglo-Swedish pharmaceutical firm announced on Tuesday it would acquire Gracell Biotechnologies, which is focused on a type of cancer therapy known as CAR-T that modifies a patient’s cells to fight the disease.
Continue reading...Researchers find turning to fatty and other unhealthy foods for solace reduces vascular function and raises risk of heart disease
Using fatty foods to comfort eat during times of stress can impair the body’s recovery from the pressure, research suggests.
Many people turn to unhealthy foods such as chocolate or crisps when they are feeling the strain, but researchers have found that this can reduce blood flow to the brain and cause poorer vascular function – which in turn can have a negative effect on mental health and cognitive function, and increase the risk of heart disease.
Continue reading...African-led trial ended a year early as researchers conclude there is ‘little or no chance’ new combination vaccines cut HIV risk
The first trial in Africa of two combination vaccines to prevent HIV has been halted after researchers concluded it was not working.
The vaccines (part of the PrEPVacc study) were being tested on 1,500 people aged between 18 and 40 in Uganda, Tanzania and South Africa.
Continue reading...Scientists complain after ‘sheer waste’ of human embryos discarded despite patients’ wishes
Leading scientists are calling for a change in the law to help IVF patients donate unused embryos to biomedical research after a collapse in donations over the past 15 years.
The increasing commercialisation of IVF, overstretched NHS clinics and cumbersome paperwork are blamed for a 25-fold decrease in the number of donated embryos. Scientists described some patients going to “extraordinary lengths” to ensure their embryos could be used for research rather than discarded, with many private clinics failing to routinely offer donation as an option.
Continue reading...UK BioBank offers up biggest ever cache of whole-genome sequences for medical research
A new era of medical discoveries, treatments and cures is on the horizon, researchers say, following the announcement that an unprecedented trove of genetic information is to be made available to scientists.
Health researchers from around the world can now apply to study the whole genomes of half a million people enrolled in UK Biobank, a biomedical research project that has compiled detailed health and lifestyle records on individuals since it began 20 years ago.
Continue reading...The resource, which is on the move to Manchester, now ranks as the world’s most important health database
The origins of the UK Biobank can be traced back to a pilot study in a building in Stockport bordered by the Cheadle Heath police station on one side and the local recreation ground on the other. It was the early 2000s and scientists had realised the potential for genomics and big data to transform health research.
With diabetes, cancer, dementia and other ailments on the rise, scientists pushed for a database devoted to genetics, health and lifestyle to help them tease apart who was most at risk and how diseases could be prevented.
Continue reading...Use of cattle from country free of mad cow disease means product is safe, experts say, and patients can still donate blood
Bone cows, specially bred in mad cow-free Australia, are being used instead of human donors for dental and medical bone grafts.
While bovine grafts have been tested for spinal fusion, foot reconstructions and to fix skull traumas, the Australian versions are predominantly used in dental work to strengthen degraded jaws before tooth implants.
Continue reading...Pollution caused twice as many premature deaths as previously thought, with updated understanding of dangers of PM2.5
Coal-fired power plants killed at least 460,000 Americans during the past two decades, causing twice as many premature deaths as previously thought, new research has found.
Cars, factories, fire smoke and electricity plants emit tiny toxic air pollutants known as fine particulate matter or PM2.5, which elevate the risk of an array of life-shortening medical conditions including asthma, heart disease, low birth weight and some cancers.
Continue reading...‘Momentous’ breakthrough as trial finds treatment for nail infections to be highly effective for neglected tropical disease
A cheap and easily taken drug used to treat fungal nail infections has been found to work against a devastating flesh and bone-eating disease found across Africa, Asia and the Americas.
Researchers say the breakthrough offers hope to thousands of patients who have suffered decades of neglect and can face amputations if the disease is left untreated.
Continue reading...Researchers say they have discovered a common type of bacteria can trigger irritation
Whether it’s a tickle of the nose, or an irritation in one’s hair, itches can be excruciating. Now scientists say they have found a common type of skin bacteria can trigger the sensation.
Crucially, as such bacteria are commonly found on the skin of patients with eczema – or atopic dermatitis – the work helps explain why such conditions can be accompanied by the urge to scratch.
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