‘It made Boris seem like a normal person’: how did Johnson’s Covid change him?

The prime minister’s spell in intensive care underscored the severity of the pandemic. Did it also make him reassess his life?

It was an unexpected twist in what already felt like an excessively dramatic disaster movie. On 6 April, the British prime minister was admitted to the intensive care ward at St Thomas’ hospital in London, after contracting a new and potentially deadly virus. Donald Trump said he was “praying for his good friend”; the French president, Emmanuel Macron, said all his wishes were with the prime minister, his family and the British people in “this difficult time”. The Labour leader, Keir Starmer, described it as “terribly sad news”.

Boris Johnson pulled through, of course, surviving to witness the birth of his son, Wilfred – given the middle name Nicholas, after the doctors, Dr Nick Price and Dr Nick Hart, who saved Johnson’s life. But more than eight months later, could the country still be feeling the impact of this dramatic turn of events?

Continue reading...

Coronavirus: key moments – timeline

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19 – here are the points where momentum shifted

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19, it has been an extraordinary year. Here’s how the momentum shifted

Continue reading...

‘Autoantibodies’ may be driving severe Covid cases, study shows

Scientists find aberrant immune system in patients with virus could also be cause of ‘long Covid’

Dramatic levels of “friendly fire” from the immune system may drive severe Covid-19 disease and leave patients with “long Covid” – when medical problems persist for a significant time after the virus has been beaten – scientists have said.

Researchers at Yale University found that Covid-19 patients had large numbers of misguided antibodies in their blood that targeted the organs, tissues and the immune system itself, rather than fighting off the invading virus.

Continue reading...

Has a year of living with Covid-19 rewired our brains?

The pandemic is expected to precipitate a mental health crisis, but perhaps also a chance to approach life with new clarity

When the bubonic plague spread through England in the 17th century, Sir Isaac Newton fled Cambridge where he was studying for the safety of his family home in Lincolnshire. The Newtons did not live in a cramped apartment; they enjoyed a large garden with many fruit trees. In these uncertain times, out of step with ordinary life, his mind roamed free of routines and social distractions. And it was in this context that a single apple falling from a tree struck him as more intriguing than any of the apples he had previously seen fall. Gravity was a gift of the plague. So, how is this pandemic going for you?

In different ways, this is likely a question we are all asking ourselves. Whether you have experienced illness, relocated, lost a loved one or a job, got a kitten or got divorced, eaten more or exercised more, spent longer showering each morning or reached every day for the same clothes, it is an inescapable truth that the pandemic alters us all. But how? And when will we have answers to these questions – because surely there will be a time when we can scan our personal balance sheets and see in the credit column something more than grey hairs, a thicker waist and a kitten? (Actually, the kitten is pretty rewarding.) What might be the psychological impact of living through a pandemic? Will it change us for ever?

Continue reading...

Origin story: what do we know now about where coronavirus came from?

When Chinese scientists alerted colleagues to a new virus last December, suspicion fell on a Wuhan market. What have health officials learned since then?

Maria van Kerkhove was staying with her sister in the US for the Christmas holidays, but checking her emails. As always. Every day there are signals of potential trouble, said the World Health Organization virologist who was to become a household name and face within weeks.

“There’s always something that happens at Christmas time. There’s always some alert, or a signal of a suspected case. The last several years it’s been Mers [Middle East respiratory syndrome] – a suspect case travelling to Malaysia or Indonesia or Korea or somewhere in Asia from the Middle East. So there’s always some kind of signal. There’s always something that happens,” she said.

Continue reading...

‘Covid-19 has an odour, and the dogs are detecting it’: meet the canine super-squad sniffing out the virus

They’re loyal, diligent – and have unbeatable noses. Could dogs play a key part in the fight against the pandemic?

A single-storey building in a lonely rural business park, a few miles from Milton Keynes on a grey autumn day. It looks like a location for a bleak thriller: where a kidnap victim is held, perhaps, or the scene of a final shootout. Inside, though, something kind of cool is happening.

In a brightly lit room, four inverted metal cups have been placed on the red carpet, each containing a small glass jar. One of these contains a smell: a “training odour”. Into the room bursts Billy, followed by Jess. Billy is a labrador, and Jess his human trainer. Billy bounces about the place, clearly super excited. He sniffs at everything – furniture, people, the cups – wagging ferociously. When he sniffs at the cup that contains the smell, another trainer, Jayde, indicates success with a clicking noise. Billy is rewarded with his favourite toy, a well-chewed rubber ball, and a chorus of “good boy”.

Continue reading...

Dogs and owners may share resemblance in diabetes risk

Research shows people who have a dog with type 2 diabetes are 38% more at risk of having disease themselves

It’s said that dogs resemble their owners, but the similarities may also extend to their risk of diabetes, research suggests. The same cannot be said of cat owners and their companions, however.

Previous studies had hinted that overweight owners tend to have porkier pets, possibly because of shared health behaviours such as overeating or not taking regular exercise. To investigate whether this extended to a shared risk of type 2 diabetes, Beatrice Kennedy, of Uppsala University in Sweden, and colleagues turned to insurance data from Sweden’s largest pet insurance company, using owners’ 10-digit national identification numbers to pull their anonymised health records.

Continue reading...

Chinese Covid-19 vaccine has 86% efficacy, UAE says

First results released from trial of Sinopharm shot involving 31,000 people

The United Arab Emirates said a Chinese coronavirus vaccine tested in the federation of sheikhdoms has 86% efficacy, in a statement that provided few details but marked the first public release of information on the performance of the shot.

The announcement brought yet another contender into the worldwide race for a vaccine to end the pandemic, a scientific effort in which China and Russia are competing with western firms to develop an effective inoculation.

Continue reading...

UK trial to mix and match Covid vaccines to try to improve potency

Pilot planned for January will give subjects a shot of both Oxford/AstraZeneca and Pfizer/BioNTech versions

A trial is likely to go ahead in January to find out whether mixing and matching Covid vaccines gives better protection than two doses of the same one, the head of the British government’s taskforce has said.

The Pfizer/BioNTech Covid jab is an mRNA vaccine. Essentially, mRNA is a molecule used by living cells to turn the gene sequences in DNA into the proteins that are the building blocks of all their fundamental structures. A segment of DNA gets copied (“transcribed”) into a piece of mRNA, which in turn gets “read” by the cell’s tools for synthesising proteins.

Continue reading...

WHO looks at giving Covid-19 to healthy people to speed up vaccine trials

Advisory meeting will discuss feasibility of human challenge trials despite first jabs becoming available

The World Health Organization is holding discussions on Monday about the feasibility of trials in which healthy young volunteers are deliberately infected with coronavirus to hasten vaccine development – amid questions over whether they should go ahead given the promising data from the frontrunner vaccine candidates.

Some scientists have reservations about exposing volunteers to a virus for which there is no cure, although there are treatments that can help patients. However, proponents argue that the risks of Covid-19 to the young and healthy are minimal, and the benefits to society are high.

Continue reading...

Coronavirus live news: Italy’s death toll passes 60,000; UK records another 231 Covid deaths

Italy has sixth highest death toll across the world; Russia reports 29,039 new cases, taking cumulative total to 2,460,770

Sick people in northern France occasionally leave garments in healing trees or “arbres à loques” in the hope of a cure, following a tradition that persists since pre-Roman times.

But recently, this tradition has been updated for the coronavirus age.

Donald Trump says his lawyer Rudy Giuliani has tested positive for coronavirus.

.@RudyGiuliani, by far the greatest mayor in the history of NYC, and who has been working tirelessly exposing the most corrupt election (by far!) in the history of the USA, has tested positive for the China Virus. Get better soon Rudy, we will carry on!!!

Continue reading...

Military planes to fly vaccines in to Britain to avoid ports hit by Brexit

Officials fear delays even after EU deal as Boris Johnson and Ursula von der Leyen order talks to resume

Tens of millions of doses of the Covid-19 vaccine manufactured in Belgium will be flown to Britain by military aircraft to avoid delays at ports caused by Brexit, under contingency plans being developed by the government.

Both the Department of Health and Social Care (DHSC) and senior sources at the Ministry of Defence (MoD) confirmed to the Observer on Saturday that large consignments would be brought in from 1 January by air if road, rail and sea routes were subject to widely expected delays after that date.

Continue reading...

Anosmia: how Covid brought loss of smell centre stage

A condition once overlooked by researchers is now in the spotlight as a key symptom of Covid-19

Seven years ago, rhinology surgeon Peter Andrews found himself performing an operation that would go on to change the course of his career.

Andrews was operating on a patient who had broken his nose many decades earlier after being struck by a cricket ball. The procedure was delicate: straightening the septum – the thin wall of cartilage that separates the nostrils – and in the process improving his breathing, which had become more laboured in later life.

Continue reading...

Coronavirus live news: UK records 397 new deaths and a further 15,539 cases; Keir Starmer forced to self-isolate

WHO says virus spreading fast despite vaccine progress; French infections rise to 2.29m; Brazil reports 627 new deaths. Follow latest updates

The US Centers for Disease Control and Prevention (CDC) on Saturday reported 14,255,535 cases of the new coronavirus, an increase of 214,099 cases from its previous count, and said that the number of deaths had risen by 2,439 to 277,825.

The CDC reported its tally of cases of the respiratory illness known as Covid-19, caused by coronavirus, as of 4 pm ET on 4 December versus its previous report a day earlier.

2000 football fans in London have started watching the first Premier League game to allow fans into a ground since March.

At 5:30pm local time, the game between West Ham and Manchester United kicked off at the London Stadium, after the ban on fans entering stadiums was lifted on 2 December.

Continue reading...

How vaccine approval compares between the UK, Europe and the US

The regulatory fast-tracking of the Covid vaccine in Britain by MHRA has led some to question its methods

The Medicines and Healthcare Products Regulatory Authority (MHRA) in the UK has not had a round of applause from anyone other than the UK’s politicians and the vaccine companies. It gave temporary authorisation to the Pfizer/BioNTech vaccine on Wednesday and within hours, the European Medicines Agency (EMA) put out a stiff statement implying more work was needed than the UK regulator had done. Its own decision could come as late as 29 December. It may well have been needled by the crowing of the health secretary, Matt Hancock, who claimed the fast approval as a Brexit triumph. He had to backtrack. The MHRA’s chief executive, June Raine, pointed out that the agency had simply taken advantage of a provision that any country in Europe could use, to fast-track approval in a pandemic.

Continue reading...

Coronavirus live news: Biden vows to get vaccinated in public; Cyprus to waive tests for vaccinated visitors

Biden will ask Americans to wear masks for his first 100 days in office; Cyprus announces new measure to ease travel; Iran’s cases top 1m

In the UK saliva tests for Covid-19, which are being introduced for NHS workers as part of the government’s mass testing programme, pick up only 13% of people with low levels of the virus and not 91%, as the official assessment has claimed, according to experts.

Two members of the Royal Statistical Society’s working group looking at the accuracy of Covid tests have questioned the results and the way they have been evaluated.

Related: Experts question claimed accuracy of Covid-19 saliva tests

Revelations of distorted corona virus tallies have caused growing controversy in Greece reports our correspondent Helena Smith in Athens.

Figures released by the government nightly have been slammed for not reflecting the truth after reports of mismanagement by the national public health organisation, EODY.

Continue reading...

Calls to investigate possible link between menopause and Covid risk

Some evidence suggests falling oestrogen levels could make older women more vulnerable

A possible link between the menopause and Covid-19 needs to be investigated, researchers have said, with some evidence suggesting that falling oestrogen levels could leave older women at increased risk from the disease.

Men are at greater risk of severe Covid, and dying of the disease, than women but recent research has suggested that in women, infections and long-lasting symptoms might be more common among those who have gone through the menopause.

Continue reading...

‘The scientists have done it’: Boris Johnson hails Covid vaccine

PM says news brings ‘sure and certain knowledge’ that people can reclaim their lives

Boris Johnson has declared that the nation is no longer resting on the hope of a return to normality by spring but instead has the “certain knowledge” that people can reclaim their lives, as he hailed the arrival of the newly approved Covid-19 vaccine.

The prime minister told a Downing Street press conference on Wednesday that “the scientists have done it”, although he stressed that people should not get carried away with “over-optimism”, insisting that they continue to abide by the rules.

Continue reading...

UK coronavirus live: Boris Johnson leads Downing Street briefing after vaccine approved for use

Latest updates: PM holds press conference after earlier warning people not to ‘get hopes up too soon’ about early vaccination

Stevens is talking about the vaccination guidelines. (See 11.23am.)

The roll-out will be phased, he says.

Johnson urges people in tier 3 areas to take part in community testing.

And people should follow the restrictions, he says.

Continue reading...

France will carry out border checks to stop skiers from spreading Covid

Coronavirus clusters in Alpine resorts played key role in early spread of virus in Europe

France will carry out random border checks over the holiday season targeting French skiers on their way to and from foreign resorts – particularly Switzerland and Spain – where slopes stay open, the prime minister, Jean Castex, has said.

“The goal is to avoid French citizens getting contaminated. That will be done by performing random checks at the borders,” Castex told French television, adding that returning holidaymakers would be ordered to quarantine for seven days.

Continue reading...