Category Archives: Medical research

Anger at plans to roll back Covid vaccines to under-11s in England

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Children aged 5-11 will no longer be offered Covid jabs, except those in clinical risk groups, UKHSA confirms

The decision to reduce the number of children who are offered Covid jabs has prompted outcry from parent groups and academics.

According to the UK Health Security Agency (UKHSA), children who had not turned five by the end of last month will not be offered a vaccination. The agency said the offer of Covid jabs to healthy 5-11-year-olds was always going to be temporary.

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Revealed: black and Asian people wait longer for cancer diagnosis in England than white people

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Exclusive: Analysis of 126,000 cases over a decade shows ‘deeply worrying’ racial disparities in NHS wait times

Black and Asian people in England have to wait longer for a cancer diagnosis than white people, with some forced to wait an extra six weeks, according to a “disturbing” analysis of NHS waiting times.

A damning review of the world’s largest primary care database by the University of Exeter and the Guardian discovered minority ethnic patients wait longer than white patients in six of seven cancers studied. Race and health leaders have called the results “deeply concerning” and “absolutely unacceptable”.

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Fears over China’s access to genetic data of UK citizens

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Biobank urged to review transfer of information for medical research

Rising political and security tensions between Beijing and the west have prompted calls for a review of the transfer of genetic data to China from a biomedical database containing the DNA of half a million UK citizens.

The UK Biobank said it had about 300 projects under which researchers in China were accessing “detailed genetic information” or other health data on volunteers.

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New ‘Parp inhibitors’ could prevent certain tumours appearing

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Breakthrough research could see some genetic cancers neutralised before they take hold and is already being used for people at risk

Sue Hayward was first diagnosed with ovarian cancer in 2017. Doctors acted swiftly and she was given a hysterectomy followed by sessions of chemotherapy.

But her cancer returned within a year. “I carry a mutated version of a gene known as BRCA1 which makes me susceptible to breast and ovarian cancers,” said Hayward, who works at the John Radcliffe Hospital, Oxford. “It runs in families. My mother died of cancer and we assume her mother did as well.”

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Half of people with possible signs of cancer wait six months to contact a GP

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Survey by Cancer Research UK shows poorer people less likely to see their family GP, reducing survival chances

Half of people with possible cancer symptoms in the UK do not contact a GP for at least six months, potentially reducing their chances of survival, research has found.

Poorer people are less likely than the better-off to see their family doctor once they have eventually sought medical help, a survey by Cancer Research UK found.

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Research on ‘molecular drills’ of skin cancer cells offers hope for treatment

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Institute of Cancer Research in London isolates gene that allows tumours to spread through the body

Skin cancer cells produce “molecular drills” to penetrate healthy tissues and spread around the body, according to research that raises the prospect of new therapies for the disease.

Researchers used robotic microscopy to capture the formation of the drills by melanoma cells that were being grown in 3D skin-like material in the laboratory.

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HPV vaccine after removal of precancerous cells may cut cervical cancer risk

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Study finds reduced risk of cervical cancer recurring after HPV vaccination post-surgery, though further research is needed

Giving women the human papillomavirus (HPV) vaccine when precancerous lesions are removed from their cervix may cut the risk of cells recurring and them getting cervical cancer, a study has found.

Cases of cervical cancer in the UK have fallen hugely since school pupils aged 13 and 14 – first girls and later boys – began being offered HPV jabs in 2008 as protection against the disease.

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Cancer researchers unable to access clinical trial data for top-selling drugs, study finds

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Lack of transparency from pharmaceutical companies on anticancer medication has implications for health equity, Australian scientist says

Clinical trial data that saw some of the world’s most widely used cancer drugs approved by the US drugs regulator remains secret, despite a pharmaceutical industry commitment to transparency made in 2014.

The authors of a study published in the journal JAMA Oncology on Friday said the lack of transparency should be concerning to Australia.

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Thai researchers test wastewater to track spread of monkeypox

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Monitoring sewage thought to be a quicker, more cost-effective way to understand the spread of the virus

Researchers in Thailand are examining wastewater for signs of monkeypox, as part of surveillance efforts to detect the spread of the virus.

Academics from Naresuan University, in Phitsanulok province, northern Thailand, began testing sewage at Bangkok’s Suvarnabhumi airport in May, adopting a technique that has also been used to track the spread of Covid-19.

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UK scientists take ‘promising’ step towards single Covid and cold vaccine

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Francis Crick Institute in London says area of spike protein of Sars-CoV-2 could form basis of jab against variants and common cold

Scientists have made a “promising” advance towards developing a universal coronavirus vaccine to tackle Covid-19 and the common cold.

Researchers at the Francis Crick Institute in London have discovered that a specific area of the spike protein of Sars-CoV-2 – the virus that causes Covid-19 – is a good target for a pan-coronavirus jab that could offer protection against all the Covid-19 variants and common colds.

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UK needs urgent vaccine drive to curb monkeypox, campaigners say

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Terrence Higgins Trust says action must be stepped up to prevent disease becoming endemic

Health authorities are underestimating the scale of the response required to stop monkeypox becoming endemic in the UK, sexual health campaigners have warned, as a new vaccination drive is launched.

The Terrence Higgins Trust urged the NHS and the UK Health Security Agency (UKHSA) to urgently pump cash into the system to pay more healthcare workers to administer vaccines. It also wants the number of doses ordered to be doubled to protect against a virus that has infected at least 2,208 people in the UK, according to the latest official figures.

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Skin cancer death rates for men in UK have tripled since 1970s

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Men 69% more likely to die from melanoma than women, says Cancer Research UK, warning that lack of sun protection is a factor

Skin cancer death rates among men have more than tripled since the 1970s, research reveals, prompting fresh warnings from experts to stay safe in the sun.

Since 1973, death rates from melanoma – the deadliest form of skin cancer – have increased by 219% in men, compared with the rise of 76% in women, Cancer Research UK found. As many as 1,400 men are now dying from the disease each year, in contrast to 980 women. This amounts to a total of six people a day, the charity said.

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Wrist-worn trackers can detect Covid before symptoms, study finds

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Sensor tech can alert wearer to Covid early, helping to prevent onward transmission

Health trackers worn on the wrist could be used to spot Covid-19 days before any symptoms appear, according to researchers.

Growing numbers of people worldwide use the devices to monitor changes in skin temperature, heart and breathing rates. Now a new study shows that this data could be combined with artificial intelligence (AI) to diagnose Covid-19 even before the first tell-tale signs of the disease appear.

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Gel that repairs heart attack damage could improve health of millions

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Injectable, biodegradable technology developed by UK team works as a scaffold to help new tissue grow

British researchers have developed a biodegradable gel to repair damage caused by a heart attack in a breakthrough that could improve the health of millions of survivors worldwide.

There are more than 100,000 hospital admissions every year due to heart attacks in the UK alone – one every five minutes. Medical advances mean more people than ever before survive, with 1.4 million Britons alive today after experiencing a heart attack. But hearts have a very limited ability to regenerate, meaning survivors are left at risk of heart failure and other health problems.

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Let doctors use MDMA to treat veterans with PTSD and depression, former ADF boss says

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Chris Barrie says he hopes common sense will prevail and the TGA will allow drug to be more readily used to treat patients

The former chief of the Australian defence force, Chris Barrie, is campaigning to remove barriers stymying doctors from using MDMA to treat veterans suffering post-traumatic stress disorder and depression, saying he hopes “common sense is going to prevail”.

Late last year, the Therapeutic Goods Administration decided against downgrading the classification of psilocybin or MDMA as a prohibited substance to a controlled substance, a move which would have increased patient access.

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Medical research stalled as NHS focuses on small number of trials, experts say

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Report outlines ‘research waste’ that occurred during the pandemic, with weakly designed trials exposing millions to unproven treatments

Government efforts to focus NHS resources on a smaller number of well-designed clinical trials could inadvertently be contributing to a backlog of stalled medical research, and result in some important trials being scrapped, researchers say.

Their warning comes as a report outlines the scale of “research waste” that has occurred during the pandemic, with rampant duplication of scientific efforts and weakly designed clinical trials exposing millions of patients to unproven treatments, with little scientific benefit.

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AstraZeneca reviews diversity in trials to ensure drugs work for all

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Firm aims to apply ‘equity lens’ across clinical tests to ensure diverse population groups take part

The pharmaceutical giant AstraZeneca is conducting a major review of diversity across its trials in an attempt to ensure its medicines work for all population groups, although it has admitted that including pregnant women is a particular challenge.

The head of oncology at Britain’s biggest drugmaker, David Fredrickson told the Guardian that the firm was among those leading efforts to improve participation of people of colour and other under-represented groups in clinical trials.

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More monkeypox cases detected in UK ‘on daily basis’, says scientist

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Twenty cases confirmed in UK amid reports of child being admitted to intensive care in London hospital

More monkeypox cases are being detected in Britain “on a daily basis”, a senior doctor has warned, amid reports that a child has been admitted to intensive care with the disease.

Dr Susan Hopkins, a chief medical adviser to the UK Health Security Agency (UKHSA), said an update on confirmed cases would be released on Monday as efforts continue to contain the outbreak using contact tracing, testing and vaccination.

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British scientist says US anti-abortion lawyers misused his work to attack Roe v Wade

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Giandomenico Iannetti, a pain expert at UCL, angrily denies that his research suggests foetuses can feel pain before 24 weeks

A University College London scientist has accused lawyers in the US of misusing his groundbreaking work on the brain to justify the dismantling of Roe v Wade, the landmark ruling that legalised abortion nationally in America.

Giandomenico Iannetti said his research, which used imaging to understand the adult brain’s response to pain, had been wrongly interpreted to make an anti-abortion argument.

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Australian researchers uncover clue to rare and severe response to Covid in children

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Breakthrough could improve diagnosis and lead to development of treatment for condition that has baffled doctors for two years

In the first months after Covid emerged, doctors were baffled by rare and severe responses to the virus in some children, whose symptoms included lung disease, blood clotting and heart damage.

Two years later and researchers led by the Murdoch Children’s Research Institute [MCRI] in Melbourne have uncovered the proteins involved in these acute inflammatory responses in children.

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