Jobs at risk without boost in research investment, peak body warns after Scott Morrison praises scientists

Australia currently spends just 1.8% of GDP on research and development, lagging OECD average

Australia risks losing jobs to other countries if it fails to lift its below-average spending on research and development, a peak science body has warned, amid Scott Morrison’s vow to promote “technology not taxes” on climate policy.

Australia invests just 1.8% of its economic output in research and development, well behind the OECD average of 2.5%.

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Can history teach us anything about the future of war – and peace?

A decade on from psychologist Steven Pinker’s declaration that violence is declining, historians show no sign of agreeing a truce

Ten years ago, the psychologist Steven Pinker published The Better Angels of Our Nature, in which he argued that violence in almost all its forms – including war – was declining. The book was ecstatically received in many quarters, but then came the backlash, which shows no signs of abating. In September, 17 historians published a riposte to Pinker, suitably entitled The Darker Angels of Our Nature, in which they attacked his “fake history” to “debunk the myth of non-violent modernity”. Some may see this as a storm in an intellectual teacup, but the central question – can we learn anything about the future of warfare from the ancient past? – remains an important one.

Pinker thought we could and he supported his claim of a long decline with data stretching thousands of years back into prehistory. But among his critics are those who say that warfare between modern nation states, which are only a few hundred years old, has nothing in common with conflict before that time, and therefore it’s too soon to say if the supposed “long peace” we’ve been enjoying since the end of the second world war is a blip or a sustained trend.

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Will the magic of psychedelics transform psychiatry?

Psychedelics have come a long way since their hallucinogenic hippy heyday. Research shows that they could alleviate PTSD, depression and addiction. So will we all soon be treated with magic mushrooms and MDMA?

Imagine a medicine that could help people process disturbing memories, sparking behavioural changes rather than merely burying and suppressing symptoms and trauma. For the millions suffering with post-traumatic stress disorder (PTSD) and depression, such remedies for their daily struggles could be on the horizon. Psychiatry is rapidly heading towards a new frontier – and it’s all thanks to psychedelics.

In an advanced phase trial published in Nature in May, patients in the US, Israel and Canada who received doses of the psychedelic stimulant MDMA, alongside care from a therapist, were more than twice as likely than the placebo group to no longer have PTSD, for which there is currently no effective treatment, months later. The researchers concluded that the findings, which reflected those of six earlier-stage trials, cemented the treatment as a startlingly successful potential breakthrough therapy. There are now hopes that MDMA therapy could receive approval for certain treatments from US regulators by 2023, or perhaps even earlier – with psilocybin, the active ingredient of magic mushrooms, not far behind in the process. (A small study at Johns Hopkins University, published last year, suggested it could be four times more effective than traditional antidepressants.)

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We can be confident there have been far more than 5 million global Covid deaths | David Spiegelhalter and Anthony Masters

Estimating ‘excess’ fatalities, a more robust analysis method, puts the pandemic’s grim toll between 10m and 19m people
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On 1 November, news organisations reported the global Covid-19 death toll had exceeded 5 million. But, as these articles highlight, this figure is likely to be a massive underestimate.

Johns Hopkins University collates official daily statistics on Covid deaths, but there is no unified global definition: Belgium’s high reported death rate partly reflects its including all probable Covid deaths in all settings, while Hungary only publishes hospital deaths with a positive test. Turkmenistan and North Korea have, apparently, not experienced a single Covid death.

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‘Our notion of privacy will be useless’: what happens if technology learns to read our minds?

The promise of neurotechnology to make lives better is growing. But do we need a new set of rights to protect the integrity of our minds?

“The skull acts as a bastion of privacy; the brain is the last private part of ourselves,” Australian neurosurgeon Tom Oxley says from New York.

Oxley is the CEO of Synchron, a neurotechnology company born in Melbourne that has successfully trialled hi-tech brain implants that allow people to send emails and texts purely by thought.

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SpaceX toilet leak forces astronauts to use diapers on trip back to Earth

  • Crew who grew first chilis in space face 20 hours in capsule
  • ‘Spaceflight is full of lots of little challenges’, US astronaut says

Astronauts who will leave the International Space Station on Sunday will have to use diapers on the way home, because of a broken toilet in their SpaceX capsule.

The Nasa astronaut Megan McArthur described the situation as “suboptimal” but manageable. She and three crewmates will spend 20 hours in the capsule, from the time the hatches are closed until a Monday morning splashdown.

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Cranberry juice won’t cut it: UTIs and the potential for repurposing drugs

The winning essay in the Max Perutz science writing award 2021, published below, was written by Vicky Bennett from the department of biology and biochemistry at Bath University

In May, PhD students who are funded by the Medical Research Council (MRC) were invited to enter the Max Perutz science writing award 2021 and write a compelling piece about their research for the non-scientific reader.

From the many entries received, the 10 that made the shortlist covered diverse topics, including dementia, childhood adversity, the role of genes in schizophrenia and the use of hypnosis to treat psychosis.

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Welsh study shows impact of Covid on 10- and 11-year-olds

Children ate less healthily, took less exercise and had more emotional problems, say researchers

Children in the UK ate fewer vegetables, took less exercise and experienced worsening emotional difficulties following the Covid outbreak, according to a research study.

A biennial survey conducted by investigators at Cardiff University found that primary school-age children reported a sharp increase in “elevated or clinically significant emotional difficulties” in early 2021, compared with the same survey conducted in 2019.

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UK is first to approve oral antiviral pill to treat Covid

Pill can be taken twice daily at home and priority will be given to elderly patients and those with health vulnerabilities

The UK medicines regulator has become the first in the world to approve an oral antiviral pill for Covid in a move that paves the way for tens of thousands of vulnerable patients to receive the treatment from this winter.

Nearly half a million doses of molnupiravir, a pill that can be taken twice daily at home, are due for delivery from mid-November and will be given as a priority to elderly Covid patients and those with particular vulnerabilities, such as weakened immune systems. The drug will initially be given to patients through a national study run by the NHS.

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‘It gave me an ability to enjoy life’: readers on cognitive behavioural therapy

Two people tell us about their experiences with CBT and how it changed their lives

The psychotherapist Aaron Beck, known as the father of cognitive behavioural therapy (CBT), died on Tuesday aged 100 at his Philadelphia home. CBT is a form of treatment that helps patients to analyse and manage negative thinking patterns rather than focusing on past conflicts. Here, two people tell us about their experiences with CBT and how it changed their lives.

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‘He was adamant he didn’t want it’: the pro-vax parents with vaccine-hesitant kids

Among under-18s, vaccine uptake is low, and there is a growing issue with misinformation spread on social media and at school. Is there anything a concerned caregiver can do?

Throughout the pandemic, Anna has worked for the NHS. She has seen the effects of Covid-19 first-hand and, although she worked remotely because she was in a vulnerable group, other colleagues – she is a physiotherapist – were deployed to Covid wards at the height of hospital admissions. “At the trust I work for, they’re setting up a long-Covid service,” she says. She comes home and her son Sam, 16, listens to her talk about it – and yet he is adamant that the coronavirus isn’t happening or that, if it is, it’s not serious. “You know: ‘Covid is a load of rubbish – it’s all about control’,” she says. “It’s all very conspiracy theory, a lot of his stuff.” He was adamant from the start that he wouldn’t be having the vaccine if and when it became available for his age group, and he has stuck to it. “He is very resistant,” says Anna. “He is pretty determined not to conform anyway. Part of it, I think, is him being a teenager, and the other bit of it is conspiracy theory: ‘It’s all a big con.’” His main source of information since the start of the pandemic has been social media, says Anna. “He watches a lot of YouTube.”

Just over a month ago, YouTube announced it would remove videos that spread misinformation about all vaccines, and would ban the accounts of anti-vax activists; it had already banned content with false claims about Covid vaccines last year. Facebook did the same in February this year, though a quick search reveals misinformation is still easy to find (one post I found within minutes claimed 80% of vaccinated women had miscarriages). On TikTok, “unvaxxed” content racks up hundreds of thousands of views. Last month, NewsGuard, an organisation that rates the credibility of news organisations and monitors misinformation, found Covid conspiracy theories were being viewed by millions on TikTok, and, in its research, children under 13 – the lower age limit – were able to access the app.

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Plant in traditional Samoa medicine could be as effective as ibuprofen, study shows

Researchers say leaves of the matalafi plant could also potentially be used to treat cancer, diabetes and cardiovascular diseases

Leaves from a plant which can be found “in back yards across Samoa” could be as effective as ibuprofen in lowering inflammation and could even be used to treat illnesses such as Parkinson’s and cancer, a new study has found.

For centuries, the leaves of the psychotria insularum plant, known locally in Samoa as matalafi, have been used in traditional medicine to treat inflammation associated with fever, body aches, swellings, elephantiasis, and respiratory infections.

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Bill Gates call for huge global effort to prepare for future pandemics

Microsoft founder says research and development budgets should focus on weaknesses exposed by rapid spread of Covid

A global research effort worth tens of billions of dollars is needed to ensure the world is better prepared for the next pandemic, which could be far worse than Covid, Bill Gates has said.

The Microsoft founder said the “completely horrific” death toll and economic damage inflicted by coronavirus should drive funding into projects aimed at improving vaccines, treatments and diagnostic tests that will be needed to contain the next pandemic more effectively.

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Covid has caused 28m years of life to be lost, study finds

Oxford researchers arrive at virus’s toll in 31 countries by looking at deaths and age they occurred

Covid has caused the loss of 28m years of life, according to the largest-ever survey to assess the scale of the impact of the pandemic.

The enormous toll was revealed in research, led by the University of Oxford, which calculated the years of life lost (YLL) in 37 countries. The study measured the number of deaths and the age at which they occurred, making it the most detailed assessment yet of the impact of Covid-19.

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Covid-19 virus does not infect human brain cells, study suggests

Exclusive: study raises hopes that Covid-related damage to sense of smell may be more superficial than previously feared

The virus that causes Covid-19 does not infect human brain cells, according to a study published in the journal Cell. The findings will raise hopes that the damage caused by Sars-CoV-2 might be more superficial and reversible than previously feared.

The study contradicts earlier research that suggested the virus infects neurons in the membrane that lines the upper recesses of the nose.

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Europe’s record summer ‘impossible’ without global heating

Cop26 countries must take action to stop record heat becoming an annual event, say experts

The heatwaves and wildfires that caused devastation in Europe this summer would not have happened without global heating, new analysis shows.

The summer of 2021 was the hottest on record in the continent, with average temperatures about 1C above normal. The elevated heat caused wildfires and premature deaths.

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Flu, cancer, HIV: after Covid success, what next for mRNA vaccines?

The technology was viewed with scepticism before the pandemic but there is now growing confidence about its use

It is one of the most remarkable success stories of the pandemic: the unproven technology that delivered the Moderna and Pfizer/BioNTech vaccines in record time, helping to turn the tide on Covid-19. The vaccines are based on mRNA, the molecule that instructs our cells to make specific proteins. By injecting synthetic mRNA, our cells are turned into on-demand vaccine factories, pumping out any protein we want our immune system to learn to recognise and destroy.

Pre-pandemic, the technology was viewed with scepticism – a clever concept, but not guaranteed to deliver. Now there is growing confidence that mRNA vaccines could have far-reaching applications in tackling diseases from flu to malaria.

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‘We are protected by prayers’: the sects hampering southern Africa’s vaccine rollout

With millions of followers, the stance of some Apostolic church leaders threatens to undermine fight against Covid

Hymnal melodies reverberate around the hillside in Kuwadzana, a Harare suburb. On a blisteringly hot Saturday, members of the Apostolic church, dressed in white, hum and sing together.

Songs, long prayers and a little Bible reading punctuate the outdoor service. It’s a spectacle for passersby.

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‘Vax’ chosen as word of the year by Oxford English Dictionary firm

Accolade reflects how use of the short form of ‘vaccine’ rose by 72 times in a year and spread across society

In a year when talk over the virtual garden fence has focused on whether you have been jabbed, jagged or had both doses yet, and whether it was Pfizer, AstraZeneca or Moderna you were injected with, Oxford Languages has chosen vax as its word of the year.

After deciding last year that it was impossible to sum up 2020 in one word, the company that produces the Oxford English Dictionary said the shorthand for vaccine had “injected itself into the bloodstream of the English language” this year during the Covid pandemic.

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New evidence suggests Vikings – and their mice – beat Portugal to the Azores

Evidence from animal remains shows Norse seafarers settled on the islands centuries before Portuguese explorers

They came from the land of the ice and snow and the midnight sun – but still ended up in some balmy destinations. This is the conclusion of researchers who have discovered evidence to support the idea that the Vikings settled on the clement shores of the Azores several hundred years before the Portuguese arrived in 1427.

Given that the Vikings are usually associated with the frozen north, the claim is startling. Nevertheless, it is based on solid science, says a group of international researchers who recently analysed lakebed sediments in the Azores, an archipelago in the mid-Atlantic.

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