‘Don’t plan it, just go!’: how to be spontaneous – and grab some unexpected fun

The pandemic has left our best-laid plans in disarray, but we can still have spur-of-the-moment adventures

Back in the wild old days, my best buddy and I used to call going out “looking for trouble”. We weren’t hoping for a punch-up or a little light robbery, but a spontaneous adventure involving music, strangers or just the city at night. All that spur-of-the-moment fun has taken quite a beating since the pandemic began, for many millions of us. First came the lockdowns, social distancing and closed venues, then the cautious reopening when even a trip to the pub or an art gallery had to be booked weeks in advance. And now, just when it seemed the world was finally getting back to normal, Omicron has come wielding its everything’s-off-again sledgehammer, crushing all those dreams of nights out, holidays and raucous parties. Not only does it seem foolish to plan anything, but after two years of frustration and self-restraint, it’s hard to summon up the enthusiasm to do anything off the cuff.

And that’s quite a loss. While we often think anticipation is half the fun, in 2016 researchers from two US universities found that people enjoyed activities more when they were impromptu. Scheduling a coffee break or a movie, for instance, made them feel “less free-flowing and more work-like”, wrote the authors. As Jane Austen put it 200 years ago in Emma: “Why not seize the pleasure at once? – How often is happiness destroyed by preparation, foolish preparation!”

Continue reading...

Roman town’s remains found below Northamptonshire field on HS2 route

Findings surpass experts’ expectations after buildings, wells, coins and wide road discovered

A wealthy Roman trading town, whose inhabitants adorned themselves with jewellery and ate from fine pottery, has been discovered half a metre below the surface of a remote field in Northamptonshire.

A 10-metre-wide Roman road, domestic and industrial buildings, more than 300 coins and at least four wells have been unearthed at the site, where 80 archaeologists have been working for the past 12 months.

Continue reading...

Will Covid-19 become less dangerous as it evolves?

Analysis: experts warn that viral evolution is not a one-way street and a continuing fall in virulence cannot be taken for granted

The pandemic has been awash with slogans, but in recent weeks, two have been repeated with increasing frequency: “Variants will evolve to be milder” and “Covid will become endemic”. Yet experts warn that neither of these things can be taken for granted.

Those stating that viruses become less deadly over time often cite influenza. Both of the flu viruses responsible for the 1918 Spanish flu and 2009 swine flu pandemics eventually evolved to become less dangerous. However, the 1918 virus is thought to have become more deadly before it became milder. And other viruses, such as Ebola, have become more dangerous over time.

Continue reading...

Maryland doctors transplant pig’s heart into human patient in medical first

Patient is doing well three days after the highly experimental surgery, doctors say, though it’s too soon to know if it is a success

In a medical first, doctors in Maryland have transplanted a modified pig’s heart into a human patient in a last-ditch effort to save his life.

Doctors at the University of Maryland medical center said Monday that the patient was doing well three days after the highly experimental surgery, though it is too soon to know if the operation has been a success.

Continue reading...

Are we witnessing the dawn of post-theory science?

Does the advent of machine learning mean the classic methodology of hypothesise, predict and test has had its day?

Isaac Newton apocryphally discovered his second law – the one about gravity – after an apple fell on his head. Much experimentation and data analysis later, he realised there was a fundamental relationship between force, mass and acceleration. He formulated a theory to describe that relationship – one that could be expressed as an equation, F=ma – and used it to predict the behaviour of objects other than apples. His predictions turned out to be right (if not always precise enough for those who came later).

Contrast how science is increasingly done today. Facebook’s machine learning tools predict your preferences better than any psychologist. AlphaFold, a program built by DeepMind, has produced the most accurate predictions yet of protein structures based on the amino acids they contain. Both are completely silent on why they work: why you prefer this or that information; why this sequence generates that structure.

Continue reading...

Coronavirus: should the UK make vaccination mandatory?

With more countries ready to oblige citizens to receive the Covid jab, what are the key questions in the debate?

In Italy, it is now obligatory for people aged 50 or over to be vaccinated against Covid-19. Greece is pondering a similar move. In France, which has seen record numbers of positive cases, President Emmanuel Macron has also announced that he wants to “piss off” the unvaccinated, while Austria is contemplating a law to make the vaccine mandatory for all its citizens. By contrast, in the UK, Boris Johnson has confined himself to accusing anti-vaxxers of talking “mumbo-jumbo”.

But is that enough? Should the UK take a harder line on those who refuse to be vaccinated? After all, this is a virus that threatens to overwhelm the NHS. As doctors continue to point out, hospital beds are now filling up with more and more seriously ill Covid patients, many of whom are unvaccinated. So, should vaccines against Covid be made mandatory, not just in certain workplace settings but for all individuals?

Continue reading...

Global spread of autoimmune disease blamed on western diet

New DNA research by London-based scientists hopes to find cure for rapidly spreading conditions

More and more people around the world are suffering because their immune systems can no longer tell the difference between healthy cells and invading micro-organisms. Disease defences that once protected them are instead attacking their tissue and organs.

Major international research efforts are being made to fight this trend – including an initiative at London’s Francis Crick Institute, where two world experts, James Lee and Carola Vinuesa, have set up separate research groups to help pinpoint the precise causes of autoimmune disease, as these conditions are known.

Continue reading...

The rise of lateral flow tests: are these ‘heroes’ of the pandemic here to stay?

After missteps and controversy, the quick and easy tests are well on way to becoming part of daily life

Once obscure diagnostic devices, lateral flow tests have had a rocky path to mainstream use, but some experts now view their rise to ubiquity as a “heroic” step in the fight against Covid-19 and say they could be here to stay.

As the first wave of Covid crashed down in early 2020 and governments scrambled to secure PPE, ventilators and reagents for laboratory testing, behind the scenes some had already foreseen a role for the pregnancy test-style kits.

Continue reading...

UK faces legal action for approving firm accused of using forced labour as PPE supplier

High court to review government’s decision to include subsidiary of Malaysia’s Supermax in £6bn ‘framework’ deal for buying gloves

The UK government is facing legal action over its decision to keep using a Malaysian company accused of using forced labour as a supplier of personal protective equipment (PPE) to the NHS.

Lawyers at the London-based law firm Wilson Solicitors have filed for a judicial review of the government’s decision to name the UK subsidiary of the Malaysian company Supermax as one of the approved suppliers in a new £6bn contract for disposable gloves for NHS workers.

Continue reading...

‘Ghost’ orchid that grows in the dark among new plant finds

Hundreds of new species include pink voodoo lily and an ylang-ylang tree named after Leonardo DiCaprio

A ghost orchid that grows in complete darkness, an insect-trapping tobacco plant and an “exploding firework” flower are among the new species named by scientists in the last year. The species range from a voodoo lily from Cameroon to a rare tooth fungus unearthed near London, UK.

A new tree from the ylang-ylang family is the first to be named in 2022 and is being named after the actor and environmentalist Leonardo DiCaprio. He campaigned to revoke a logging concession which threatened the African tree, which features glossy yellow flowers on its trunk.

Continue reading...

Could microclots help explain the mystery of long Covid? | Resia Pretorius

My lab has found significant microclot formation in long Covid patients. Unfortunately, these are missed in routine blood tests

One of the biggest failures during the Covid-19 pandemic is our slow response in diagnosing and treating long Covid. As many as 100 million people worldwide already suffer from long Covid. That staggering number will eventually be much higher, if we take into account that diagnoses are still inadequate, and that we still do not know what the impact of Omicron and future variants will be.

Patients with long Covid complain of numerous symptoms, the main ones being recurring fatigue and brain fog, muscle weakness, being out of breath and having low oxygen levels, sleep difficulties and anxiety or depression. Some patients are so sick that they cannot work or even walk a few steps. There is possibly also an elevated risk of stroke and heart attacks. One of the biggest sources of concern is that even mild and sometimes asymptomatic initial Covid-19 infection may lead to debilitating, long-term disability.

Continue reading...

Parts of NHS may be overwhelmed by Covid wave, admits Boris Johnson

PM says England can ‘ride out’ Omicron without lockdown but acknowledges service is under huge pressure

Parts of the NHS may be overwhelmed in the coming weeks, Boris Johnson has admitted for the first time as he insisted England can “ride out” its biggest ever Covid wave “without shutting down our country once again”.

The prime minister acknowledged the health service is under huge pressure after four more NHS trusts – all outside London – declared critical incidents amid rising staff absences and Covid patients. On Tuesday evening hospitals across Greater Manchester announced some non-urgent surgery and appointments would be suspended.

Continue reading...

Detained, missing, close to death: the toll of reporting on Covid in China

Activists say crackdown is driven by Xi Jinping, who has ‘declared a war on independent journalism’

Chen Kun was living in Indonesia with his wife and daughter when he learned from his brother Mei’s boss that he had been “taken away for investigation” by Chinese police.

He immediately suspected it was to do with his brother’s website, a citizen news project called Terminus 2049. Since 2018 Mei, his colleague Cai Wei, and Cai’s partner – surnamed Tang – had been archiving articles about issues including #MeToo and migrant rights, and reposting them whenever they were deleted from China’s strictly monitored and censored online platforms. It was April 2020, and for the last few months Terminus 2049 had been targeting stories about the Covid-19 outbreak and response.

Continue reading...

When will Omicron peak in the UK and is the modelling wrong?

Analysis: gloomiest predictions may have not come to pass, but experts caution that we’re not out of the woods yet

The family gatherings have disbanded, the new year’s hangovers have lifted. Despite record Covid infection figures over the holiday period, evidence that the rate of increase in cases may be slowing has prompted speculation that London, at least, may be close to reaching “peak Omicron”.

Boris Johnson is said to be obsessed with this hypothetical time point, seeing it as crucial to how the Covid variant may play out nationwide. If hospitalisations follow the same trajectory and peak without the NHS being overwhelmed, the prime minister’s decision not to impose lockdown-style restrictions before the holiday period may be vindicated.

Continue reading...

Fossil hunter Richard Leakey who showed humans evolved in Africa dies at 77

Kenyan conservationist found oldest near-complete human skeleton in 1984, dating from 1.5m years ago

The celebrated Kenyan conservationist and fossil hunter Richard Leakey, whose groundbreaking discoveries helped prove that humankind evolved in Africa, has died aged 77.

The president of Kenya, Uhuru Kenyatta, announced Leakey’s death with “deep sorrow”.

Continue reading...

Super poo: the emerging science of stool transplants and designer gut bacteria

As more people turn to faecal transplants for their health benefits, researchers in Adelaide are harnessing the power of high-quality poo in new treatments that can simply be swallowed

Good poo donors are so hard to find they’re sometimes called “unicorns”. These elusive, healthy creatures service a market for faecal transplants that is growing rapidly as evidence of its benefits mounts.

Emerging science shows that a human’s microbiome – their constellation of gut microbes – has a far greater effect on health than anyone previously imagined. This enormous ecosystem we host in our bodies includes bacteria, fungi, viruses and more.

Continue reading...

To the moon and beyond: what 2022 holds for space travel

From lunar missions to anti-asteroid defence systems, there are plenty of exciting scientific developments to look forward to

This year promises to be an important one for space exploration, with several major programmes reaching the launch pad over the next 12 months. The US is to return to the moon, undertaking a set of missions intended to establish a lunar colony there in a few years. China is expected to complete its Tiangong space station while Europe and Russia will attempt to land spacecraft on Mars, having failed at every previous attempt. India, South Korea and Japan are also scheduled to put a number of missions into space.

Continue reading...

We often fail to keep resolutions – but writing in a notebook brings great rewards

Scribbling down our thoughts is a great way to make sense of things – and very satisfying

In 1989, when I was 16, I moved into a pub with my parents and my younger brother, Matty. It was highly exciting. I took to barwork as I liked the chat, and also enjoyed the opportunities offered for eavesdropping. I was curious about the adult world and up until then had learned most of what I knew from books. Now I had all these real lives to study. I should write some of this down, I thought, and would scribble into my diary before bed.

We couldn’t believe how busy it was that first Christmas, culminating on New Year’s Eve, when everyone piled out into the main street at midnight and exchanged drunken embraces and warm wishes for 1990. After the pub had emptied and the mammoth job of clearing up was done, we gathered with our staff for a few drinks and the chat turned to resolutions. All the women wanted to lose weight. A couple of people wanted to stop smoking. I announced very firmly that I wanted to write a novel.

Continue reading...

Can you think yourself young?

Research shows that a positive attitude to ageing can lead to a longer, healthier life, while negative beliefs can have hugely detrimental effects

For more than a decade, Paddy Jones has been wowing audiences across the world with her salsa dancing. She came to fame on the Spanish talent show Tú Sí Que Vales (You’re Worth It) in 2009 and has since found success in the UK, through Britain’s Got Talent; in Germany, on Das Supertalent; in Argentina, on the dancing show Bailando; and in Italy, where she performed at the Sanremo music festival in 2018 alongside the band Lo Stato Sociale.

Jones also happens to be in her mid-80s, making her the world’s oldest acrobatic salsa dancer, according to Guinness World Records. Growing up in the UK, Jones had been a keen dancer and had performed professionally before she married her husband, David, at 22 and had four children. It was only in retirement that she began dancing again – to widespread acclaim. “I don’t plead my age because I don’t feel 80 or act it,” Jones told an interviewer in 2014.

Continue reading...

Your attention didn’t collapse. It was stolen

Social media and many other facets of modern life are destroying our ability to concentrate. We need to reclaim our minds while we still can

When he was nine years old, my godson Adam developed a brief but freakishly intense obsession with Elvis Presley. He took to singing Jailhouse Rock at the top of his voice with all the low crooning and pelvis-jiggling of the King himself. One day, as I tucked him in, he looked at me very earnestly and asked: “Johann, will you take me to Graceland one day?” Without really thinking, I agreed. I never gave it another thought, until everything had gone wrong.

Ten years later, Adam was lost. He had dropped out of school when he was 15, and he spent almost all his waking hours alternating blankly between screens – a blur of YouTube, WhatsApp and porn. (I’ve changed his name and some minor details to preserve his privacy.) He seemed to be whirring at the speed of Snapchat, and nothing still or serious could gain any traction in his mind. During the decade in which Adam had become a man, this fracturing seemed to be happening to many of us. Our ability to pay attention was cracking and breaking. I had just turned 40, and wherever my generation gathered, we would lament our lost capacity for concentration. I still read a lot of books, but with each year that passed, it felt more and more like running up a down escalator. Then one evening, as we lay on my sofa, each staring at our own ceaselessly shrieking screens, I looked at him and felt a low dread. “Adam,” I said softly, “let’s go to Graceland.” I reminded him of the promise I had made. I could see that the idea of breaking this numbing routine ignited something in him, but I told him there was one condition he had to stick to if we went. He had to switch his phone off during the day. He swore he would.

Continue reading...