Coronavirus live: Portugal delays Lisbon lockdown easing; highest daily cases in Russia since March

Capital and three other municipalities will remain under restrictions until at least 27 June due to rise in infections; Russia reports 10,407 new cases

Some of the UK’s biggest care home operators have told the Guardian they repeatedly warned Matt Hancock’s department about the risk of not testing people discharged from hospitals into care homes in March 2020.

Their claims are likely to increase pressure on the health secretary when he appears before MPs on Thursday to defend his handling of the Covid pandemic to a parliamentary inquiry.

Related: Matt Hancock ‘was warned of Covid care home risk in March 2020’

The US is in talks with drugmaker Moderna Inc to buy more Covid-19 vaccine doses for global supply, CNBC reported on Wednesday citing a source.

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Quantum leap for medical research as microscope zooms in on tiny structures

Australian scientists develop a microscope that works with 35% more clarity, raising hope for improvements in medical imaging

Australian researchers have developed a microscope that can image tiny biological structures that were previously not visible in what has been described as a significant step for quantum technology.

It is believed to be the first time that quantum technology has improved on existing light microscopes, which in future may lead to improvements in medical imaging and navigation systems.

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Covid distancing may have weakened children’s immune system, experts say

End of social distancing and mask-wearing could leave children vulnerable to common bugs

Scientists are concerned that measures to combat Covid-19 have weakened the immune systems of young children who have not been able to build up resistance to common bugs, leaving them vulnerable when mask-wearing and social distancing eventually end.

Contact with viral pathogens happens on a fairly regular basis and although it does not always lead to sickness, the exposure helps shore the immune system against the threat should the bugs be encountered again.

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Leading biologist dampens his ‘smoking gun’ Covid lab leak theory

Nobel laureate David Baltimore says he overstated case, and the origins of the virus are still unknown

A Nobel prize-winning US biologist, who has been widely quoted describing a “smoking gun” to support the thesis that Covid-19 was genetically modified and escaped from a Wuhan lab, has said he overstated the case.

David Baltimore, a distinguished biology professor, had become one of the most prominent figures cited by proponents of the so-called lab leak theory.

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Nasa spacecraft captures first closeups of Jupiter’s largest moon in decades

Juno passed within 645 miles of Ganymede, the closest any spacecraft has come to the moon since 2000

Nasa’s Juno spacecraft has provided the first closeups of Jupiter’s largest moon in two decades.

Juno zoomed past icy Ganymede on Monday, passing within 645 miles (1,038km). The last time a spacecraft came that close was in 2000 when Nasa’s Galileo spacecraft swept past our solar system’s biggest moon.

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What could a delay to the 21 June lockdown easing mean for England?

Analysis: with ministers said to be considering England’s 21 June easing, how delay could affect vaccinations and virus spread

Ministers are said to be considering delaying the easing of lockdown in England on 21 June for somewhere between two weeks and a month. We look at what a delay could mean, and how long it may need to last.

Why delay?

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‘Birds are here for everyone’: how Black birdwatchers are finding a community

In a 2011 study by the Fish and Wildlife Service, 93% of birders surveyed were white while just 4% were Black

“This is my form of therapy,” says Mariana Winnik, a third-grade teacher and avid birdwatcher from Brooklyn. Wearing a T-shirt with illustrations of birds and wielding a pair of binoculars and a trusty bird identification app, Winnik makes her way through north Central Park, on a mid-morning Saturday walk led by Christian Cooper.

Cooper says he doesn’t usually lead bird walks because of the responsibility that comes with it. “I feel awful if we go out and we don’t see a lot of good birds,” he says.

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24,000-year-old organisms found frozen in Siberia can still reproduce

Russian scientists find bdelloid rotifers deep in remote permafrost

A microscopic worm-like creature, labelled an “evolutionary scandal” by biologists for having thrived for millions of years without having sex, has now been shown to persist for at least 24,000 years in Siberian permafrost and then reproduce, researchers have found.

Multicellular invertebrates that are solely female, bdelloid rotifers are already renowned for their resistance to radiation and ability to withstand rather inhospitable environments: drying, starvation and low oxygen. They’ve also existed for at least 35m years – and can be found today in freshwater lakes, ponds, streams and moist terrestrial habitats such as moss, lichen, tree bark and soil.

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FDA approves first new Alzheimer’s drug in almost 20 years

Usefulness of aducanumab is disputed but US approval will trigger push to make it available globally

A controversial new drug for Alzheimer’s disease, the first in nearly 20 years, was approved in the US on Monday, which will trigger pressure to make it available worldwide in spite of mixed evidence over its efficacy.

While doctors, patients and the organisations that support them are desperate for treatments that can slow mental deterioration, the usefulness of the new drug, aducanumab, is disputed by scientists. Two trials were stopped in March 2019 because the drugs appeared not to work. The manufacturer, Biogen, said the drugs were unlikely to improve people’s memory and thinking.

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A victim of its own success: how Taiwan failed to plan for a major Covid outbreak

Once a poster child for blocking coronavirus, Taiwan failed to fully prepare a pandemic response or vaccination rollout

While most of the world suffered through hundreds of millions of cases and millions of deaths from Covid-19, the 23.5 million people in Taiwan largely lived a normal life, thanks to a well-documented strong and early response that saw it go 250 days without a single local case. It lobbied for inclusion in the World Health Organization’s decision-making body off the back of its undeniable success and expertise under the slogan “Taiwan can help”.

But now the tables have turned and the island itself is in need of assistance, after an outbreak that started among airline staff in April spread across the island. The government appears to have been caught short by something it thought would never happen: the poster child for outbreak prevention had apparently failed to fully prepare an outbreak response.

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Could a third wave of Covid be more serious than UK’s first two?

Analysis: Concern over Delta variant means decision on ending restrictions on 21 June hangs in balance

Summer has nearly arrived and the UK is beginning to unlock from coronavirus restrictions, with a full lifting still on the cards in England on 21 June.

Yet the spectre of the Delta variant is casting an ominous shadow, with concerns it could fuel a third wave. So just how serious could the next peak be – and could it be more serious than Britain’s first two waves?

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My best friend at school moved in with us – and taught me to trust again

How a close and enduring relationship forged in the school playground turned my life around

My school bully came in an unlikely package. She was a bushy-haired, bespectacled, briefcase-carrying pocket rocket who made my life miserable for a significant portion of Year 8 when I was 12 years old. I met her on the first day at our large and rowdy comprehensive school. With all my existing friends assigned to different forms, I was on high alert for someone to attach myself to as soon as possible. With her outwardly gawky appearance, she seemed like the ideal candidate and I approached her with the rather arrogant assumption that she would jump at the chance of my friendship.

It didn’t take me long to realise I’d severely misjudged the situation. Her meek physical persona belied a serious rebellious streak and I struggled to keep up from the start. When she dared me to join her in “the jungle” – a wooded area of the school grounds off limits to students, I shakily agreed. We eluded capture from the lunchtime supervisors who patrolled its perimeters, but my time in the jungle brought me little exhilaration or pleasure. More tests and challenges soon followed, all proposed with a glint in her eye that I came to dread.

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Covid Delta variant ‘about 40% more transmissible’, says Matt Hancock

Under-30s to be offered jabs from next week but variant makes decision on easing rules in England ‘more difficult’

The new Delta variant of coronavirus appears to be about 40% more transmissible than the variant it has largely replaced, Matt Hancock has said, making government decisions about whether to ease restrictions in England on 21 June “more difficult”.

Saying that under-30s in England will be called to begin vaccinations from next week, the health secretary confirmed it was still possible the reopening programme could be delayed or some rules kept in place.

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Data on Delta variant splits scientists on lifting final Covid restrictions

Sage group advises against easing social distancing on 21 June, but others say it is too early to assess risks

Health experts remain divided over the dangers posed by the new Delta variant of Covid-19 and the risks it poses to the nation as ministers consider whether or not to lift lockdown later this month.

Some argue that the new variant, first identified in India, is a significantly increased threat to the UK and have urged that delays be imposed on the total removal of social restrictions, due on 21 June.

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HIV after Covid: Anthony Fauci and an army of researchers seek to regain momentum

In the summer of 1981, public health professionals faced a terrifying crisis. Their work helped shape victories against the current pandemic – but some fear hard-won ground is lost

As Anthony Fauci marks 40 years since HIV emerged, he regrets how the extraordinary disruptions that Covid-19 have wreaked upon society have hampered efforts to tackle the major pandemic that preceded it.

Related: 'Brand-new disease, no treatment, no cure': how Anthony Fauci's fight against Aids prepared him to tackle Covid-19

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Why self-belief is a superpower that can be harnessed

Lockdowns may have eroded people’s swagger, but research suggests there are ways to remedy the situation

In July 2007, the Irish golfer Padraig Harrington won one of golf’s most coveted competitions, the British Open. The story of how he did this, one of the most remarkable finishes in golfing history, illustrates one of the ways confidence works.

The Claret Jug – the Open’s famous prize – was within Harrington’s grasp as he teed off at the penultimate hole of the tournament. He had a one-shot lead on his arch-rival, Sergio García. He was entirely in the zone – “I am literally the most confident person at that point in time,” he said later. Then, something strange happened – a twinge of doubt came out of nowhere at the top of his back swing and he sliced the ball into the murky waters of the notorious Barry Burn river.

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‘We are born hungry for faces’: why are they so compelling?

We’ve spent a year obscured by masks and pixellated by Zoom. Are you ready to go back to reading real-life facial expressions in all their fascinating glory?

This has been the year of a thousand faces. Every face is an inch or two high on my laptop screen, and trapped inside a rectangle. The rectangles form a wall of faces that builds up brick by brick. As each new face arrives, the wall shifts and rearranges itself. Outside, in the real world, other people’s faces have been frustratingly elusive, half-hidden by masks. Or they have averted their gaze, focused on completing their essential journeys and not wishing to exchange their spittle with mine. But here the faces keep coming, popping up magically from wherever they are in the world, happy to be seen.

During lulls in meetings, my eyes scan the virtual room. You can look long and hard at people’s faces online in a way that would be rude in real life. I have never before paid this much attention to how a hairline runs along the top of a forehead, or an eye sits in its socket, or a jawline segues into a neck. I hadn’t noticed how vulnerable faces are – so soft, fleshy and bruisable – and how mercurially they move between moods. The faces look by turns dazed, dogged, sweetly attentive, full of faraway thoughts that no one could guess at, and as if they are trying hard to be bright-eyed and smiley but might suddenly dissolve into tears. It’s been that kind of year.

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Ancient tsunami could have wiped out Scottish cities today, study finds

Research maps the extent of the catastrophic Storegga tsunami 8,200 years ago for the first time

Towns and cities across Scotland would be devastated if the country’s coastline was hit by a tsunami of the kind that happened 8,200 years ago, according to an academics’ study.

While about 370 miles of Scotland’s northern and eastern coastline were affected when the Storegga tsunami struck, the study suggests a modern-day disaster of the same magnitude would have worse consequences.

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SpaceX rocket heads to ISS with a supply of squid, toothpaste and avocados

Rocket due to reach the International Space Station this weekend is loaded with 7,300lb of fresh food and supplies for an orbiting lab

SpaceX has launched a supply mission bound for the International Space Station on Thursday, carrying with it thousands of tiny sea creatures along with a plaque-fighting toothpaste experiment and powerful solar panels.

The 7,300lb (3,300kg) shipment – which also includes fresh lemons, onions, avocados and cherry tomatoes for the station’s seven astronauts – should arrive Saturday.

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Drug may help more women survive hereditary breast cancer

International trials of olaparib were stopped early as benefits of ‘groundbreaking’ drug became clear

Women with hereditary breast cancer, triggered by the BRCA1 or BRCA2 genes, stand a better chance of survival following successful trials of a drug that cuts the likelihood of the cancer returning after treatment.

A major trial carried out by academic researchers to see whether olaparib can prevent recurrence was stopped early – after two-and-a-half years instead of the planned 10 years – when the benefits of the drug became clear.

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