What we know about the South African variant of Covid

Experts say 501Y.V2 variant is more infectious and resistant to vaccines, though there are no signs that it leads to more severe disease

The South African variant, like the new UK variant, contains a mutation known as N501Y which is believed to make the virus more contagious than older variants. The South African variant also contains other mutations of concern, including E484K and K417N. These two mutations are thought to explain why the South African variant appears to be better able to evade neutralising antibody responses by the body.

Continue reading...

Is it possible to change a chicken’s sex before it hatches?

Billions of unwanted male chicks are slaughtered by the farming industry. Now a startup claims to have found a surprising solution to the problem

The eggs we eat have a hidden cost. About 7bn male chicks are killed worldwide every year to produce them. Farmers need to replenish their supply of egg-laying hens but, by nature, half the chicks that hatch are male and growing them for meat is uneconomic – that industry uses faster growing breeds. In many countries they are tossed into shredding machines, although in the UK they are gassed.

But what if those male chicks could instead hatch out as functional females, able to grow into egg-laying birds? That’s the vision of Israeli startup Soos Technology. Founded in 2017, the company, which has received $3.3m in investment and prize winnings, wants to make commercial hatcheries kinder and more economic by changing the effective sex of poultry embryos as they develop.

Continue reading...

I’m an NHS consultant anaesthetist. I see the terror in my Covid patients’ eyes

As a hospital consultant working in intensive care, the reality of coronavirus and patients’ fear is brought home to me every day

I’m not ready,” the patient implores me through her CPAP [continuous positive airway pressure] hood. She’s breathing at more than triple her normal rate and I’ve been asked to intubate her as she’s deteriorating, despite three days in intensive care. She is 42 years old.

There’s terror in her eyes. A tear runs down her cheek. She’s looking at the patient opposite who is in an induced coma, intubated and ventilated, and isn’t doing well.

Continue reading...

Professor Avi Loeb: ‘It would be arrogant to think we’re alone in the universe’

When Harvard professor Avi Loeb discovered possible signs of extraterrestrial activity, it caused a scandal in the research community. Is fear and conservatism stopping science from considering plausible evidence that there are aliens out there?

By the time humanity noticed the object, it was already leaving the solar system. 19 October 2017. Astronomers at the University of Hawaii notice an odd shape tumbling away from Earth, a bright speck hurtling through the deep dark. Informally, they name it ‘Oumuamua, from the Hawaiian for “scout”, and classify it an interstellar asteroid, the first known to visit our solar system. Really, nobody could be sure what it was. Asteroids are rocky and dull and commonly round, but ‘Oumuamua was shiny and elongated. Astronomers had first thought it a comet, but comets have bright gassy tails, and here there wasn’t one. The more data was collected, the more mysterious the object seemed. “Time after time it looked unusual,” says the astrophysicist Avi Loeb, over Zoom. “At some point it crossed a threshold for me. And at that point you say, ‘OK, come on!’”

Loeb is the Frank B Baird Jr Professor of Science at Harvard and, until recently, the longest-serving chair of Harvard’s department of astronomy. When we speak, he is in his home office – big old fireplace, books about the cosmos, a remarkable quantity of dark wood – preparing to discuss his new book, Extraterrestrial, in which he argues an exotic hypothesis: that ‘Oumuamua was “designed, built and launched by an extraterrestrial intelligence”. Loeb is 59, but energised like a child. “I should tell you,” he warns, gently teasing, a few days after the US Capitol is stormed. “Today I’m supposed to be interviewed by Fox News. Some people said, ‘Avi, don’t do it. How could you do that?’ And I said, ‘Look, science doesn’t have a political agenda – we should speak to everyone!’”

Continue reading...

In the search for Covid protection, Cormac the ‘extremely charismatic’ llama may hold a key

The llama has provided nanobodies that effectively prevent infection, but the use of other species in Covid research raises troubling ethical questions

Cormac the llama lives a quiet life on a farm in Washington State, totally unaware that his unique immune system may be key to protecting the developing world from Covid-19.

“He is an extremely charismatic llama … he’s a pretty cool guy,” says TJ Esparza, a neuroscientist at the Uniformed Services University. He is part of the team attempting to transform Cormac’s nanobody cells into a drug that will coat the inside of human lungs, providing temporary but effective protection from coronavirus particles.

Continue reading...

‘Find of the century’: medieval hoard of treasures unearthed in Cambridge

Graves found under demolished student halls are providing valuable insight into life in a post-Roman settlement

An early medieval graveyard unearthed beneath student accommodation at Cambridge University has been described as “one of the most exciting finds of Anglo-Saxon archaeology since the 19th century”.

King’s College discovered the “extensive” cemetery, containing more than 60 graves, after demolishing a group of 1930s buildings which had recently housed graduates and staff in the west of the city, to make way for more modern halls.

Continue reading...

‘I wanted to give something back’: the academic who signed up for the Novavax trial

Librarian says she feels ‘very lucky’ working from home, so she volunteered for the vaccine test

While many have endured almost a year of stress and hardship during the Covid crisis in the UK, others have remained relatively unscathed.

Caroline Ball, a 37-year-old academic librarian from just outside Derby, has even felt guilty at times, having the good fortune of a stable job which she can do from home and not worrying about homeschooling children.

Continue reading...

Coronavirus live news: Coachella festival cancelled; fears over Australian vaccine

Shock and anger at EU’s move to invoke Brexit clause on Irish border; Fauci says ‘virus will continue to mutate’ as Democrats aim to fast-track Covid relief plan; Johnson & Johnson one-dose Covid vaccine shown to work

Hello everyone, I’m Molly Blackall, taking over the blog in London. I’ll be bringing you all the key updates in the coronavirus pandemic around the world over the next few hours.

If you spot something you think we should be reporting on in this blog, please feel free to drop me a message on Twitter. Tips and pointers always much appreciated!

The former Northern Ireland secretary Julian Smith has weighed into the row over the EU’s threat to override part of Northern Ireland Protocol under its coronavirus vaccine controls, calling it “almost Trumpian.”

The Tory MP told BBC Radio 4’s Today programme: “Years have been spent trying to ensure goods will flow freely and there will be no hard border and last night the EU pulled the emergency cord without following any of the process that are in the protocol if one side wants to suspend it.

And they did that, in my view, without anywhere near the understanding of the Good Friday Agreement, of the sensitivity of the situation in Northern Ireland, and it was an almost Trumpian act.

It is not just a backdoor for goods going to Britain, it is a very sensitive place and we have a duty of care between the EU and the UK to preserve no hard border and stability in Northern Ireland.

Related: EU in U-turn over move to control vaccine exports to Northern Ireland

Continue reading...

Everyday Covid mistakes we are all still making

Can we do more as individuals to help slow the spread of coronavirus? We ask the experts

Covid-19 infections in the UK are reducing but remain stubbornly high, despite a month of lockdown measures. So could we be doing more as individuals to curb transmission of the virus? A virologist, a psychologist and a public health expert share their views on some of the Covid-19 mistakes that we are all still making.

Continue reading...

Will Covid-19 sniffing dogs allow fans back into sporting events?

The Miami Heat will employ canines to sniff out the virus among fans attending games. But can dogs be trained in time to work at the Super Bowl?

Nearly 100 million people are expected to watch Super Bowl LV in Tampa, the first time the big game has been held during a pandemic (the World Series has survived two). But only 22,000 of those viewers, 7,500 of them vaccinated healthcare workers, will be in actual attendance, representing just one-third the capacity of Raymond James Stadium. Social distancing and face-coverings will be enforced. The first few rows will be kept clear as a buffer between the field and the fans. By this stage of the pandemic, everyone should be aware that, at any one time, a portion of the population is composed of asymptomatic carriers who can infect others they come into contact with. As a result, any large gathering has the potential to become a super-spreader event with wide-reaching consequences. Large-scale testing at gatherings such as sporting events is limited by the availability of trained personnel, equipment, money, and the time it takes for the results of the actual test to work.

But an unconventional solution may be in the works.

Continue reading...

How effective is the Novavax Covid vaccine and will it work against variants?

Everything you need to know about the trial results for a new coronavirus vaccine

In an interim analysis of a phase 3 clinical trial conducted in the UK, the vaccine has shown 89% efficacy, with 27% of participants in the trial – almost 4,000 people – older than 65. That trial suggested 95.6% efficacy against the original coronavirus and 85.6% efficacy against the more recent UK strain. Those results were based on the first 62 cases of Covid-19 identified among volunteers, with 56 cases among those given a placebo against just six in those given the vaccine.

Continue reading...

Box seat: scientists solve the mystery of why wombats have cube-shaped poo

Unique physiology allows the Australian marsupial to produce square-shaped faeces that may aid communication

How wombats produce their cube-shape poo has long been a biological puzzle but now an international study has provided the answer to this unusual natural phenomenon.

The cube shape is formed within the intestines – not at the point of exit, as previously thought – according to research published in scientific journal Soft Matter on Thursday.

Continue reading...

Why has Germany advised against Oxford/AstraZeneca jab for over-65s?

Explainer: Move attributed to ‘insufficient data’ but experts say no evidence vaccine doesn’t work

German authorities have advised that the Oxford/AstraZeneca jab should not be given to those aged 65 or above. We take a look at why, and what experts make of it.

Why has Germany advised the Oxford/AstraZeneca jab should only be used in adults under 65?

Continue reading...

Remnants of mosque from earliest decades of Islam found in Israel

Archaeologists say foundations excavated in Tiberias are of a mosque built in about AD670

Archaeologists in Israel say they have discovered the remnants of an early mosque believed to date to the earliest decades of Islam during an excavation in the northern city of Tiberias.

The foundations of the mosque, excavated just south of the Sea of Galilee by the Hebrew University of Jerusalem, point to its construction roughly a generation after the death of the prophet Muhammad, making it one of the earliest Muslim houses of worship to be studied by archaeologists.

Continue reading...

How UK spent £800m on controversial Covid tests for Dominic Cummings scheme

US firm Innova believed to be largest beneficiary of contracts after selling millions of Covid tests that are dividing opinion

Dominic Cummings’ plan to test millions of people a day for coronavirus led the government to spend over £800m on quick turnaround tests that were later found in a pilot to give the wrong results as much as 60% of the time, the Guardian can reveal.

Operation Moonshot, a mass testing scheme championed by the prime minister’s former chief adviser, prompted the government to buy huge numbers of so-called lateral flow tests from a company owned by a little-known US private equity house.

Continue reading...

Scientists liken long Covid symptoms to those of Ebola survivors

Experts also studying similarities with lasting effects of Chikungunya virus in hope of finding new treatments

Scientists are studying the similarities between long Covid and ongoing symptoms experienced by survivors of Ebola and Chikungunya virus in the hope of devising new treatments to improve their health.

Like patients with long Covid, survivors of these other, relatively new human viruses, often experience lingering symptoms which can make it difficult to work or function in everyday life.

Continue reading...

Coronavirus live news: Madrid suspends vaccinations after running out of doses; Cyprus eases lockdown

Madrid health authorities announce two-week pause after supply issues; Cyprus welcomes fall in number of new infections

The British home secretary Priti Patel has outlined new rules for tighter border controls amid unprecendented pressure on the UK health service and over 100,000 Covid-19 deaths.

Patel said too many people are coming in and out of the country every day, but told MPs on Wednesday more details will be set out by the health department next week.

Firstly, the police have stepped up checks and are carrying out more physical checks at addresses to ensure that people are complying with the self-isolation rules.

Second, we will continue to refuse entry to non-UK residents from red-list countries which are already subject to the UK travel ban.

The European Union health commissioner has said that AstraZeneca has committed to providing the bloc with doses from four plants, including two in Britain, Reuters reports.

Stella Kyriakides told a news conference that the company had legal obligations to comply with the contract.

Continue reading...

Here are five ways the government could have avoided 100,000 Covid deaths | Devi Sridhar

The UK needs to learn from the lessons of the past year and come up with a concrete plan to avert a disastrous third wave

Yesterday Britain passed a grim milestone. A further 1,631 deaths from Covid-19 were recorded, taking the official tally above 100,000, though data from the Office for National Statistics suggests the total number will now be nearer 120,000. In a briefing, Boris Johnson has said his government did everything it could to minimise the loss of life, but these deaths were far from inevitable. While the number of UK deaths has entered the hundreds of thousands, New Zealand has recorded only 25 deaths from Covid-19 so far. Taiwan has recorded seven, Australia 909, Finland 655, Norway 550 and Singapore 29. These countries have largely returned to normal daily life.

In the first year of the pandemic, the UK faced three big challenges. Our national government had no long-term strategy for suppressing the virus beyond a continual cycle of lockdowns. Even now we still don’t know what the government’s plans for the next six months are. In the early days of the pandemic, the UK treated Covid-19 like a bad flu. The government halted testing, and the initial plan seemed to be allow the virus to run unchecked through the population (the “herd immunity” approach). Finally, ministers have pitted the economy against public health, instead of realising that the health of the economy depends upon a healthy population.

Continue reading...

AstraZeneca vaccine may not be given to older people, says EU medicines chief

European Medicines Agency approval could stipulate age range, suggests Emer Cooke

The Oxford/AstraZeneca vaccine may be authorised only for younger people in Europe, because there is insufficient data on how well it works in the over-65s, the head of the regulatory body has suggested.

The European Medicines Agency (EMA) is expected to authorise the AstraZeneca vaccine at the end of this week, a month after it was approved in the UK.

Continue reading...