Magic mushrooms’ psilocybin may help heavy drinkers cut back

Positive results in first ‘rigorous’ trial investigating compound’s effect on alcohol use

The most rigorous test yet of psilocybin as a treatment for alcoholism has found that the compound in psychedelic mushrooms helped heavy drinkers cut back or quit entirely.

Psilocybin, found in several species of mushrooms, can cause hours of vivid hallucinations. Indigenous people have used it in healing rituals and scientists are exploring whether it can ease depression or help longtime smokers quit.

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Mexico’s citizens caught in crossfire as cartels launch attacks across the country

Brazen strikes by organised crime leaders have left bystanders killed as many question the president’s security policies

For Carlos Holguín it was supposed to be just another day of toil.

After leaving the factory where he works morning shifts in the Mexican border city of Ciudad Juárez, the 24-year-old began his nightly routine last Thursday as a food app delivery driver.

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New ‘Parp inhibitors’ could prevent certain tumours appearing

Breakthrough research could see some genetic cancers neutralised before they take hold and is already being used for people at risk

Sue Hayward was first diagnosed with ovarian cancer in 2017. Doctors acted swiftly and she was given a hysterectomy followed by sessions of chemotherapy.

But her cancer returned within a year. “I carry a mutated version of a gene known as BRCA1 which makes me susceptible to breast and ovarian cancers,” said Hayward, who works at the John Radcliffe Hospital, Oxford. “It runs in families. My mother died of cancer and we assume her mother did as well.”

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‘Very good for tourists’: Thailand aims for high season with U-turn on cannabis

The once-banned drug is now on sale at market stalls, beach clubs and even hotel receptions. But the laws in this ‘pot paradise’ are blurry

A distinctive sweet smell wafts through Fisherman’s Village night market on the Thai island of Koh Samui, drifting up between the sticky mango rice stalls and bucket cocktail vans. The Samui Grower cannabis stall is doing swift business tonight. A table is laid with glass jars, each displaying a different flowering green bud, with labels saying things like ‘‘Road Dawg’ hybrid THC25% 850TBH/gram”.

Elsewhere on the island, at Chi beach club, tourists lie on couches puffing ready-rolled joints and munching pizzas topped with green cannabis leaves. On Instagram, the Green Shop Samui offers a marijuana menu of fantastically named buds: Truffle Cream, Banana Kush and Sour Diesel, alongside hemp cookies and cannabis herbal soap.

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Rishi Sunak and Liz Truss facing Tory members in Leeds for first official leadership hustings – UK politics live

Leadership rivals bid to win members’ support in foreign secretary’s home town

Drug-related deaths in Scotland fell by nine in 2021, according to the latest figures released by National Records of Scotland, the first decrease since 2013 but falling well short of the significant reduction that campaigners are calling for.

The latest figure of 1,330 is still the second highest annual total on record, and Scotland continues to have by far the highest drug death rate recorded by any country in Europe and five times the rate in England.

We’ve had a raft of reports, policies and strategies that say what needs to change, and families are more likely to be included round the table, but it’s much harder to track their influence on the ground. We don’t understand what’s getting in the way of good words becoming good deeds.

1,330 of our fellow Scots have died entirely preventable deaths and we should not be celebrating this as an achievement ... The solutions are no secret. We need action, not reports with recommendations that are never implemented.

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‘Every part is useful’: the man who wants Afghanistan to swap opium for hemp

Oil from the versatile plant makes cannabis medicine CBD and its fibre has a range of uses but the Taliban need convincing

The smell seemed unmistakable, the dried buds looked familiar and the Taliban checkpoint guards, who had never heard of CBD, a non-psychoactive cannabis compound, were disgusted by the pungent cargo of Amin Karim’s truck.

“They said to me: ‘Aren’t you ashamed of yourself, Haji?’” using an honorific for an older man, as they poked through the piles of hemp headed for Kabul last October.

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Leading figures urge drugs firm to lower price of ‘game-changing’ HIV prevention drug

Signatories including Olly Alexander, Stephen Fry and Joseph Stiglitz issue a letter asking ViiV to make cabotegravir affordable to low- and middle-income countries

Nobel laureates, business leaders, former premiers and celebrities have urged a UK pharmaceutical company to lower the price of its groundbreaking HIV prevention drug and ensure it is not kept “out of reach” of the world’s poor.

In a letter signed by dozens of high-profile figures, including Sir Richard Branson, the singer Olly Alexander, the economist Joseph Stiglitz and Helen Clark, the former prime minister of New Zealand, the pharmaceutical company ViiV Healthcare is praised for having developed the first of a new kind of HIV prevention drug.

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Plantwatch: green allies – the plants that helped UK’s war effort

With medical and food supplies hit, volunteers foraged in the British countryside for useful species


In the second world war tonnes of deadly nightshade leaves and roots were collected to extract atropine, a drug used for eye operations. Foxgloves were harvested for digitalis, the powerful drug used for regulating abnormal heart rhythms – abundant foxgloves found in the Chilterns were rich in digitalis. And in the first world war sphagnum moss found in bogs was used as a highly absorbent and naturally antiseptic wound dressing, and a million dressings a month were sent to military hospitals around the world by the end of the conflict.

These were some of more than 80 wild plant species recruited during the world wars to make up for the vital pharmaceutical supplies that had been imported from Germany but which were cut off in wartime. There were other valuable wild plants, such as rose hips made into a syrup rich in vitamin C, which was in short supply because of severely limited fruit supplies.

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Australians over 70 granted access to Covid antiviral treatments

From Monday, access will also be expanded to over 50s and Aboriginal and Torres Strait Islander people over 30 with two or more risk factors

All Australians over 70 with Covid will be eligible to take antivirals from Monday, after the health minister, Mark Butler, expanded access to the treatments.

Butler revealed that access will also be expanded to people aged over 50 with two or more risk factors for severe disease and Aboriginal and Torres Strait Islander people aged over 30 with two or more risk factors.

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Mob-style killings shock Netherlands into fighting descent into ‘narco state’

Murders, corruption and ‘Mocro Maffia’ prompt Dutch to set up war chest to tackle wave of organised crime sweeping nation

Journalists and lawyers under protection or murdered on the streets, court hearings guarded by the army, witness statements anonymised, and billions in dirty drug money that leaches through society, corrupting as it goes.

This is the Netherlands, where these facts have now inspired a crackdown pitting some €500m a year against a level of organised crime that politicians fear is increasingly “undermining” public order.

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Germany’s move to legalise cannabis expected to create ‘domino effect’

Coalition government consults health experts, economists and growers in race to clear legal hurdles within two years

Germany is mulling over the consequences of soon becoming the world’s largest potential market for legally sold cannabis, as the country’s left-liberal government presses ahead with plans to allow the controlled distribution of the drug among adults.

Olaf Scholz’s coalition government has in recent weeks reiterated its 2021 coalition-deal vow to legalise for recreational use what its Green and liberal party minister have taken to referring to as Bubatz, a slang word for weed popular among German rappers.

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War on drugs prolonged Colombia’s decades-long civil war, landmark report finds

Truth commission’s report, touted as a chance to heal after half a century of bloodshed, called for a ‘substantial change in drug policy’

The punitive, prohibitionist war on drugs helped prolong Colombia’s disastrous civil war, the country’s truth commission has found, in a landmark report published on Tuesday as part of an effort to heal the raw wounds left by conflict.

The report, titled “There is a future if there is truth” was the first instalment of a study put together by the commission that was formed as part of a historic 2016 peace deal with the leftist rebels of the Revolutionary Armed Forces of Colombia (Farc).

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Australia’s first fixed pill testing site to launch in Canberra with hopes of sparking a national initiative

Organisers say the centre is a ‘real watershed’ moment and will open two nights a week from 19 July

Australia’s first fixed pill testing site will be up and running within weeks, and the organisers hope it could be the start of a national program.

A pill testing trial at Canberra’s Groovin the Moo festival in 2019 potentially saved seven lives after the program detected “toxic” chemicals mixed into drugs.

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MDMA trials under review in Canada over alleged abuse of study participants

Health Canada confirms reviews into trials following complaint of ‘alleged investigator misconduct’

All clinical trials into the psychoactive drug MDMA are being reviewed by Canadian regulators after complaints about abuse of study participants by a trailblazing American psychedelic research organization.

The California-based Multidisciplinary Association for Psychedelic Studies (Maps) has led the way in conducting trials into the medicinal qualities of the drug. In May 2021, it released results from a phase-three trial in the journal Nature on the benefits of the drug – commonly sold illegally as a powder or within ecstasy tablets – as a breakthrough treatment for PTSD, for which there is currently no effective pharmaceutical treatment.

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NHS to offer women in England drug that cuts recurrence of breast cancer

Abemaciclib can improve chances of certain type of cancer not returning after surgery by more than 30%

Thousands of women in England with breast cancer are to benefit from a new pill on the NHS which reduces the risk of the disease coming back.

The National Institute for Health and Care Excellence (Nice) has given the green light to abemaciclib, which cuts the chance of breast cancer returning after a patient has had surgery to remove a tumour.

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Doctors warn against over-medicalising menopause after UK criticism

Seeing natural event as hormone deficiency requiring treatment could increase women’s anxiety, say medics

Doctors have hit back at critics saying they are failing menopausal women, and said that treating menopause as a hormone deficiency that requires medical treatment could fuel negative expectations and make matters worse.

Writing in the British Medical Journal they said there was an urgent need for a more realistic and balanced narrative which actively challenges the idea that menopause is synonymous with an inevitable decline in women’s health and wellbeing, and called for continued efforts to improve awareness about the symptoms and how to deal with them.

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How cannabis-fed chickens may help cut Thai farmers’ antibiotic use

Scientists observed fewer cases of avian bronchitis and superior meat after chickens given cannabis

It all began when Ong-ard Panyachatiraksa, a farm owner in the north of Thailand who is licensed to grow medicinal cannabis, was wondering what to do with the many excess leaves he had amassed. He asked: could his brood of chickens benefit from the leftovers?

Academics at Chiang Mai University were also curious. Since last January they have studied 1,000 chickens at Ong-ard’s Pethlanna organic farm, in Lampang, to see how the animals responded when cannabis was mixed into their feed or water.

The results are promising and suggest that cannabis could help reduce farmers’ dependence on antibiotics, according to Chompunut Lumsangkul, an assistant professor at Chiang Mai University’s department of animal and aquatic sciences, who led the study.

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Canada air crew caught up in ‘hellish’ Dominican Republic drugs bust begs for repatriation

Five-member crew was detained after they found a bag of cocaine on 5 April and spent nine days in jail in a ‘hellish situation’

A five-person Canadian airline crew caught up in a drug-trafficking investigation is begging their government to repatriate them after two months trapped in the Dominican Republic.

“It’s absolutely horrendous – terrible, terrible stuff we’re going through,” said captain Robert Di Venanzo, who said he and his crew could be held for up to a year while an investigation proceeds.

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Thailand to ease cannabis rules but smokers warned over smell ‘nuisance’

People will be allowed to grow it at home but smoking for recreational purposes is still forbidden

Thailand will soon ease its rules on cannabis and allow people to grow the plant at home – but smoking for recreational purposes is still forbidden, and officials have warned that anyone who creates a smell by doing so in public could be charged.

From Thursday, Thailand will remove cannabis and hemp plants from its narcotics list, part of a drive to tap into the growing interest in infused drinks and medical treatments.

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Jamal Edwards died after taking recreational drugs, says his mother

Loose Women panellist Brenda Edwards says she was in ‘state of shock’ after finding out how son died

The music entrepreneur and YouTube star Jamal Edwards died from arrhythmia as a result of taking recreational drugs, his mother has said.

Edwards, who helped launch the careers of Dave and Ed Sheeran, died in February aged 31. Brenda Edwards, a singer and Loose Women panellist, said in a statement on Tuesday she was in a “state of shock” after finding out how he died.

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