Are we getting any closer to understanding long Covid?

Extreme fatigue, brain fog, sleep disturbances, chest pain and skin rashes. These are just a few of the on-going symptoms of long Covid, a disorder that can persist for many months after an initial Covid infection. With such a vast range of symptoms, and health organisations stretched to capacity by the acute stage of the disease, long Covid has continued to remain something of a mystery.

But with numerous studies trying to understand what exactly people are suffering from, progress is being made. Ian Sample speaks to Prof Akiko Iwasaki about what we do and don’t know about long Covid, and how the vaccine could reveal clues about what’s behind the disorder

Archive: Channel 4 News, Sky News

Continue reading...

First patients of pioneering CAR T-cell therapy ‘cured of cancer’

Cancer-killing cells still present 10 years on, with results suggesting therapy is a cure for certain blood cancers

Two of the first human patients to be treated with a revolutionary therapy that engineers immune cells to target specific types of cancer still possess cancer-killing cells a decade later with no sign of their illness returning.

The finding suggests CAR T-cell therapy constitutes a “cure” for certain blood cancers, although adapting it to treat solid tumours is proving more challenging.

Continue reading...

Netherlands fertility doctor used own sperm to father 21 children

Investigation into Jos Beek matches his DNA with children of mothers he treated between 1973 and 1986

A gynaecologist in the Netherlands conceived 21 children and potentially dozens more using his own sperm after prospective parents turned to him for fertility treatment, an investigation has discovered.

Jos Beek worked at Elisabeth hospital in Leiderdorp, now part of Alrijne hospital, between 1973 and 1998. He died in 2019.

Continue reading...

Scientists developing single test to detect risk of four cancers in women

Experts may be able to predict risk of developing ovarian, breast, womb and cervical cancers using cells from routine smear test

Scientists are developing a “revolutionary” test to predict a woman’s risk of four cancers using a single sample collected during cervical screening.

Using cervical cells from a routine smear test, experts may be able to spot ovarian and breast cancer or predict their likelihood of developing, according to two papers published in the journal Nature Communications. Further results are due on the ability of the WID-test – women’s cancer risk identification – to predict womb and cervical cancer, researchers said.

Continue reading...

‘The scariest thing’: the children living with long Covid

Though still rare, the numbers of kids across the US reporting symptoms long after infection are increasing, doctors say

Javanese Hailey found her daughter hunched over in pain inside their home in Manassas, Virginia, about 32 miles south-west of Washington DC.

The nine-year-old could barely walk because her stomach hurt so much, Hailey said, recalling that Sunday evening in October.

Continue reading...

Australia news live updates: protests as prime minister grilled at National Press Club; 77 Covid deaths nationally; RBA ends bond buying

Scott Morrison announces packages for aged care and NDIS as anti-vaccine protesters mass outside the National Press Club; 77 Covid deaths recorded across NSW, Victoria, Queensland and South Australia. Follow updates live

O’Neil:

A pay rise that lasts up until the next election is a cynical political ploy, because we know this plan ... will not do anything more than hold this thing together by a thread.

The truth is that the aged-care sector – the average experience of a person in aged care today is one of neglect.

The truth is that we have a crisis in aged care that has been eight years in the making.

Scott Morrison has cut aged-care funding personally as treasurer twice. One of the first actions of the incoming government was to cut the wages of aged-care staff and now we are expected to believe that this is going to make a difference?

Continue reading...

World better protected against Covid if rich nations donated 50% of vaccines to low-income countries

Vaccine inequity will prolong pandemic and increase risk of new variants developing, modelling finds

The world would be better protected against new Covid variants and there would be substantially fewer deaths in low and middle-income countries if rich nations donated half of their vaccine doses, new research suggests.

The modelling study found it was in wealthy nations’ self-interests to donate doses because vaccine inequity would prolong the pandemic and increase the risk of new variants developing.

Continue reading...

No 10 set for U-turn over mandatory Covid jabs for NHS staff in England

Minister says lower severity of Omicron variant ‘opens the window for us to look at it’

Downing Street appears likely to drop its policy of dismissing frontline NHS and care staff in England who refuse Covid vaccinations, a minister has strongly indicated, after nursing and care organisations called for this to happen.

A decision would be made “in the course of the next few days”, according to Simon Clarke, the chief secretary to the Treasury. He said the lower severity of the Omicron variant of Covid did “open a space” for the policy to be reversed.

Continue reading...

Omicron: what do we know about ‘stealth’ subvariant BA.2?

Omicron’s ‘close cousin’ has mutations that could alter how it behaves and has begun to surpass Covid’s most common variety in parts of Europe and Asia

The highly transmissible Omicron variant of the Sars-CoV-2 virus – the most common form of which is known as BA.1 – now accounts for nearly all of the coronavirus infections globally.

Though Covid cases have already peaked in some countries, scientists are now tracking a rise in cases caused by a close cousin of Omicron known as BA.2, which is starting to outcompete BA.1 in parts of Europe and Asia. The following is what we know so far about the new subvariant.

Continue reading...

Micromanagement, credit stealing, bullying: Are you a jerk at work?

We’ve all been there: driven half mad by the colleague who micromanages, the boss who bullies, the co-worker asleep on the job… So how do we navigate the messy world of office politics?

Twenty years ago, the American psychologist Tessa West began arriving early to the department store at which she worked, so she could avoid the salespeople she spent most of her time with. Really, she was hoping to escape just one colleague – someone with whom she disagreed about shop-floor etiquette. (Her: don’t steal clients. The co-worker: why not?) In the early mornings, West could be sure they wouldn’t run into each other, saving her from stress and anxiety, which can lead to ill health. “It’s not that I thought anything bad was going to happen,” she recalls, via Zoom. “It was the not-knowing what would happen,” and “the increase in heart-rate” that comes with that uncertainty. Soon the situation became so preoccupying that West quit, not so much resolving the conflict as bypassing it altogether. “Did it work? Sure. But how much energy did that take up? A lot.”

West, who is now 40, is a professor of psychology at New York University, where she runs the West Interpersonal Perception Lab, a research unit that studies, broadly, how we deal with each other, and how those interactions affect our mental and physiological states. “I spent the first 10 years of my career doing basic science on how people communicate,” she says, which included “a lot of time in labs evoking horrible experiences to see what people do.” (One study involved West sitting participants in a chair and “being mean” to them, to measure their stress responses.) Before long, she noticed that a lot of what she was observing could be captured in the workplace: how individuals influence groups, how status affects persuasion and morale, how anxiety affects everyday relations. And the more she researched, the more she realised that, like her younger self, very few of us know how to resolve everyday conflict at work.

Continue reading...

‘Like sewage and rotting flesh’: Covid’s lasting impact on taste and smell

Many sufferers have been left unable to eat due to long-term distortions to their senses

Four months after getting sick with Covid, Anne-Héloise Dautel couldn’t eat anything at all. “I just wanted to vomit, I was gagging at everything around me,” she said. “I couldn’t even stand my own smell. I was showering five times a day.” Coffee, toothpaste, shampoo and roast meat were the worst. By the time she went to hospital, she weighed just 46kg.

Severe weight loss and kidney failure are some of the impacts of smell and taste distortions which leave people unable to eat or drink things they loved, like coffee or bacon, because they smell like rotting flesh or sewage.

Continue reading...

NT chief minister says Omicron ‘too infectious’ for lockdowns to work as nation records at least 88 Covid deaths – As it happened

Michael Gunner says lockdowns and lockouts no longer effective; At least 88 Covid deaths recorded around the country as Kerry Chant says Omicron sub-variant is circulating in NSW; Queensland reveals back-to-school plan. This blog is now closed

Albanese says Labor will boost aged-care funding, but cannot specify by how much.

There has been a boost.

Two things they haven’t done: One is to tie that funding of actual delivery of better healthcare for aged-care residents in terms of some of the regulatory measures required that were recommended by the royal commission, but the big missing piece in this workforce, we still don’t have a commitment to have a nurse in a nursing home.

We still don’t have a commitment to increase in the number of other care workers in aged care, and we still don’t have a commitment to increases in wages and conditions so that aged-care facilities are able to attract the staff.

Quite clearly there will be a need for increased health funding, but there is a need also to look at the particular areas of funding.

GPs, for example. One of the reasons there is so much pressure on the hospitals is we have GP shortages in terms of training, we have GP shortages in terms of some of the changes that they’ve made to the Medicare schedule that have had an impact in our regions.

Continue reading...

Covid live: UK government reports a further 72,727 cases and 296 deaths; Russian daily infections above 100,000 for first time

Daily figures for UK are lowest since mid-December; Japanese infections set record for fifth consecutive day

In the UK, a heavily redacted report by the senior civil servant Sue Gray on parties at Downing Street will be published imminently, the Guardian understands.

It comes after Scotland Yard provoked fury and confusion by revealing it had demanded key details of the worst offending be removed. MPs labelled the Metropolitan police a broken organisation after the force admitted it had asked Gray to make “minimal reference” in her inquiry report to matters its officers were now investigating.

Continue reading...

Long Covid study finds abnormality in lungs that could explain breathlessness

Findings raise possibility Covid may cause microscopic damage not detected by normal tests

Abnormalities have been identified in the lungs of long Covid patients that could offer a potential explanation for why some people experience breathlessness long after their initial infection.

The findings, from a pilot study involving 36 patients, raise the possibility that Covid may cause microscopic damage to the lungs that is not detected using routine tests.

Continue reading...

Is it time to ditch cloth face masks for FFP2 or next-generation alternatives?

As the Covid pandemic has unfolded, the choice of face coverings has mushroomed

During the early days of the pandemic the choice was simple: you either wore a reusable cloth mask or a disposable surgical mask. As the months have progressed, the choice of face coverings and other forms of protection has mushroomed, while the emergence of more transmissible variants has prompted some countries to mandate the wearing of filtering facepiece (FFP) masks in public spaces.

Although face coverings are no longer legally required in England, the government has suggested continuing to wear one in crowded, enclosed spaces where you may come into contact with people you do not normally meet.

Continue reading...

Cold baths, cherry juice and sleep: the secret to staying fit in your 40s

Despite aching backs and stiff joints, a growing number of elite athletes – from Zlatan Ibrahimović to Serena Williams – are pushing the clock back. So why can’t you? We ask the experts how to do it


Six years ago it looked as if Zlatan Ibrahimovic’s footballing career was approaching the final whistle. After Sweden’s early exit from Euro 2016, the striker announced his retirement from international competition. At 34, he was getting on a bit for an elite athlete. Cut to November 2021 and, days after firing in a spectacular free-kick for his club, AC Milan, Sweden’s record goalscorer was helping keep alive his country’s hopes of making the next World Cup. The retirement chat was over. “I am trying to prove that 40 is just a number,” he said.

Ibrahimovic had joined what feels like a growing club: the quadragenarian athlete holding back the clock. In an era of ever more punishing professional sport, these twilight stars seem to challenge notions that youth trumps all else. Members include American football superstar Tom Brady (44), the tennis legends Venus and Serena Williams (41, 40), Roger Federer (40), and Oksana Chusovitina (46), the eight-time Olympic gymnast from Uzbekistan.

Continue reading...

Lifting England Covid rules while 3bn people unvaccinated reckless – experts

Scientists warn Boris Johnson that failure means new Covid variants will put thousands of lives at risk across UK

Boris Johnson has been accused of taking a reckless approach to public health by lifting all plan B Covid restrictions in England while failing to take enough action to get jabs to 3 billion unvaccinated people in poorer countries.

The prime minister has robustly defended his record on the pandemic this week while awaiting the findings of the Sue Gray report on the “partygate” scandal, insisting he “got the big calls right” on the biggest global health crisis in a century.

Continue reading...

Protests flare across Poland after death of young mother denied an abortion

Family of Agnieszka T say they want to ‘save other women in Poland from a similar fate’, as case met with anger over restrictive termination laws

Protests are under way across Poland after the death of a 37-year-old woman this week who was refused an abortion, a year since the country introduced one of the most restrictive abortion laws in Europe.

On the streets of Warsaw on Tuesday night, protesters laid wreaths and lanterns in memory of Agnieszka T, who died earlier that day. She was pregnant with twins when one of the foetus’ heartbeat stopped and doctors refused to carry out an abortion. In a statement, her family accused the government of having “blood on its hands”. Further protests are planned in Częstochowa, the city in southern Poland where the mother-of-three was from.

Continue reading...

Care home Covid rules to be relaxed in England allowing more visitors

Easing of restrictions comes as legal requirements for masks and NHS passes are dropped

Care home residents in England will be able to receive unlimited visitors from Monday as the restrictions to tackle the Omicron variant are eased, the Department of Health has said.

Self-isolation periods will be reduced from 14 days to 10 days for those residents who test positive, with further reductions if they test negative on days five and six.

Continue reading...

How Covid killed the one-night stand – and made us all kinkier

There has been a sharp drop in one-off encounters, researchers say, but more people are enjoying friends with benefits and getting experimental in bed

A one-night stand, people used to say, is like a short story: if it is any good, you want it to go on for longer; if it isn’t, you could have done with 15 minutes’ more sleep. To which the retort is: sure – but a lot of people really like short stories.

A lot of people, in the pre-pandemic days, used to really like one-night stands, too. The sex therapist Jenny Keane hosts a wide-ranging sex chat through her Instagram account. On it, one woman wrote appreciatively: “The sex is purely focused on pleasure. You’re not thinking about your relationship dynamics, them not doing the dishes. It’s about being served and cared for physically. It can be a very empowering and beautiful thing.”

Continue reading...