Greater Manchester lockdown delay ‘could lead to overwhelmed hospitals’

Stretford and Urmston MP urges government to strike deal with local leaders over tier 3 financial aid

Downing Street must urgently strike a deal with Greater Manchester leaders to introduce tougher Covid restrictions before hospitals are overwhelmed, the shadow education secretary, Kate Green, has said.

Deputy mayors and other civic leaders in the metropolitan region said in a joint statement on Friday they were “ready to meet at any time” with the prime minister to agree a way forward over the introduction of a tier 3 lockdown. They say the government’s initial proposals did not provide adequate financial support.

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Covid reinfections ‘to be expected’ as virus spreads, say government scientists

Reports suggest timeframe between recovery and reinfection ‘relatively short’ for those who contracted virus twice

Government science advisers have warned that reinfections with Covid-19 are “to be expected” as the virus spreads, based on what is known about people’s immunity to other coronaviruses that cause the common cold.

Researchers on the Covid-19 Genomics UK Consortium said it was unclear at what point people who had recovered from the virus became vulnerable to reinfection, but cited emerging reports of second infections that suggested the timeframe was “relatively short”.

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Brexit: No 10 says ‘trade talks over’ and tells Barnier to cancel London trip unless he’ll compromise – live

PM says there will be no deal with EU unless there is ‘fundamental change’ in Brussels

From my colleagues Pamela Duncan and Niamh McIntyre

From tonight over half the population of England will be living in areas classed as “high risk” or “very high risk” under the government’s three-tier system, equivalent to 28.4m people.

All of Lancashire county (Lancashire, Blackburn with Darwen and Blackpool council areas) are to move from tier 2 to the higher tier 3 category from midnight, meaning more than 3m people are now living in the highest-risk areas.

Trade negotiations often involve threats to walk away, and dire forecasts, before both side agree to compromise, and Brexit-watchers have been waiting for the UK-EU trade talks to this moment. It came this morning, when Boris Johnson used a TV statement (see 12.29pm) to say that there would no deal without a “fundamental change” in the EU’s approach.

But threats only work if people take them seriously and Johnson’s comments do not seem to have been taken as a sincere statement of intent to talk away. It was telling that, despite being asked twice if he was saying the talks were over, he would not use those words. (See 12.41pm.) If the foreign exchange markets thought Johnson was abandoning hopes of a deal, the pound would have fallen (as it has repeatedly in key moments in the Brexit drama since 2016). But it didn’t. “Market participants see comments from Boris Johnson as mainly political posturing at this stage,” an analyst told Bloomberg.

The pound fluctuates between gains and losses after Boris Johnson says the nation is preparing for a thin, Australia-style trade deal with the EU https://t.co/lzBTCqlY8F pic.twitter.com/YbntZLyFca

There’s no point in trade talks if the EU doesn’t change its position. The EU effectively ended the trade talks yesterday.

Only if the EU fundamentally changes its position will it be worth talking.

What I would say to that is there is only any point in Michel Barnier coming to London next week if he’s prepared to discuss all of the issues on the basis of legal text in an accelerated way without the UK being required to make all of the moves, or if he’s willing to discuss practicalities of areas such as travel and haulage which the PM mentioned in his statement.

Our position is a clear one. Only if the EU fundamentally changes position will it be worthwhile talking.

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Wales facing ‘circuit breaker’ lockdown of two or three weeks

First minister says countrywide restrictions are top option being considered

Wales is facing a “circuit breaker” lockdown of two or three weeks to stop hospitals being overwhelmed, as the country reaches what the government described as a “critical point”.

Ministers will spend the weekend coming to a final decision on their next steps, but the Welsh first minister, Mark Drakeford, said on Friday a “fire-break” or circuit breaker for the whole country was the option most actively being considered.

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Remdesivir has very little effect on Covid-19 mortality, WHO finds

Results of major trial described as sobering, with drug found not to improve survival rates

Remdesivir, one of the big treatment hopes for Covid-19, has very little effect on preventing deaths, according to a large and comprehensive trial run by the World Health Organization.

The drug, made by the US biotech firm Gilead, has been talked up as a potential cure and was taken by Donald Trump. A trial in the US had previously showed it reduced the length of stay in hospital. But the gold-standard Solidarity WHO trial, which was based on a far larger sample – 3,000 people on the drug, compared with as many who were not – showed remdesivir had little effect on deaths over 28 days.

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Coronavirus: what has changed about what we know? – video explainer

Covid-19 has spread around the world, sending millions of people into lockdown as health services struggle to cope. From symptoms and long Covid to vaccines and treatments, the Guardian's health editor, Sarah Boseley, explains what we now know about the virus that we did not at the beginning of the crisis

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Third of newborns with Covid infected before or during birth – study

Review of reported neonatal cases finds most babies with virus contract it in hospital

Nearly a third of coronavirus infections in newborn babies are picked up in the womb or from the mother during labour, a review of reported cases has found.

While Covid-19 is rare in newborns, doctors have been keen to understand the potential risks that babies face should tests reveal they have the infection soon after birth.

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Coronavirus Australia live updates: Daniel Andrews’ office vandalised as pressure grows to lift lockdown

Police investigating damage to premier’s electorate office overnight, mass testing taking place in Shepparton amid cluster, and health authorities issue warning about south-west Sydney cluster. Follow live

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  • The prime minister’s office has accidentally released its daily talking points to the media, again. This is allegedly an accident although it is a wonderful shortcut because sending the talking points gets reporters to report on the talking points, without the prime minister or others having to do any actual talking. True efficiency in government.

    Three bits may be of particular interest to readers of this blog.

    No one is saying it’s easy to get by without a job which is why the Morrison government is absolutely focused on helping unemployed Australians be work ready and creating jobs so working-age Australians have the opportunity to gain financial independence.

    A wild deer has been spotted in Sydney. Again.

    You may recall that last week two wild deer were spotted on the loose in Sydney’s inner suburbs, and police managed to capture one of them but not the other.

    Citybound motorists are warned to take extra care after a deer was seen in the Pyrmont area about 5.30am. Police are seeking specialist assistance from the RSPCA. Anyone who sees the deer is urged not to approach it and call police.

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    Covid could overwhelm NHS without more curbs, northern leaders told

    Decision expected on whether to extend tier 3 rules to Greater Manchester and Lancashire

    Deaths from coronavirus will continue to rise for at least three weeks and the NHS risks being overwhelmed unless the strictest curbs are imposed on another 4 million people, leaders in northern England have been told.

    A decision on whether to extend tier 3 restrictions – closing pubs and restaurants and banning household mixing – to Greater Manchester and Lancashire is expected on Thursday.

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    ‘Not just a dog bite’: why India is struggling to keep rabies at bay

    The government is being urged to dispel myths and ensure drugs are available – and take responsibility for the millions of stray dogs

    By the time the patient, a young man, reached Dr Ramesh Masthi at a Bengaluru hospital, it was too late to save him. After being bitten by a pack of stray dogs as he went out to buy some milk, his family had applied a paste of green chillis, then lime juice and finally, when the wound looked gruesome, turmeric.

    “He came about a week after he was bitten. The wound was serious, and we couldn’t save him. There is so much ignorance about dog bites and myths. A rabies shot in time would have saved him,” Masthi says.

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    Coronavirus Australia latest updates: Andrews and Berejiklian face no-confidence votes, as Queensland election heats up

    Victoria’s premier weathers upset after his top public servant resigned and NSW premier holds on after Icac revelations. In Queensland, opposition leader Deb Frecklington faces questions over event with Peter Dutton. Follow live

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  • Full Australian Covid stats; Covid restrictions state by state
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  • The Queensland Liberal National Party has categorically denied claims it referred its own party leader, Deb Frecklington to the electoral commission over concerns about her fundraising events.

    The ABC reported this morning that the party referred Frecklington to the Electoral Commission of Queensland over a series of events, one where Peter Dutton was a guest, involving property developers.

    NSW Health have set up a pop-up testing clinic, and alerted to more venues, after two GPs in the Sydney suburb of Lakemba tested positive for Covid-19.

    Both doctors worked at the A2Z Medical Clinic, and are linked to a patient who was previously diagnosed with Covid-19, who attended Lakemba Radiology.

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    England’s simpler three-tier Covid system may not be enough

    New rules should cut infection rates but are too late and open to abuse, say scientists

    The three-tier Covid alert system is a significant shift in the government’s approach to the coronavirus crisis in England, and, while scientists broadly welcomed the simplified rules, there are concerns the restrictions come too late and are open to abuse.

    A major benefit of the new system is that it clears up the confusing and messy patchwork of different rules in different places, which arose as regions in northern England, the Midlands and other parts of the country battled to contain local outbreaks. With simplicity and stability should come better compliance, and with that more control of the epidemic.

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    ‘Drastic rise’ in Malawi’s suicide rate linked to Covid economic downturn

    Lack of specialist support and growing unemployment are factors in growing mental health crisis, doctors say

    One Tuesday morning in March, 48-year-old farmer Lokoliyo Bwanali set off for his maize plot. He never came back. Neighbours discovered his body later in the small field where he had poisoned himself.

    “The wife of the deceased said her late husband was under pressure from creditors and was failing to settle his debts,” said Edward Kabango, from Malawi’s Dedza district police department. “The deceased left his home without explaining to his family members where he was heading until he was later found lying dead in a field, a kilometre from his home.”

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    Coronavirus Australia live: Victoria reports 15 new Covid cases as NSW on high alert

    Victorian bar owner lodges legal challenge to the constitutionality of the state’s lockdown as fears in NSW grow over number of locally transmitted cases. Follow all the latest updates

    Australian scientists have discovered that the virus that causes Covid-19 can survive for up to 28 days on surfaces such as the glass on mobile phones, stainless steel, vinyl and paper banknotes.

    The virus survived longer on paper banknotes than on plastic banknotes and lasted longer on smooth surfaces rather than porous surfaces such as cotton.

    Related: Virus that causes Covid-19 can survive up to 28 days on surfaces, scientists find

    Today is the first day in more than two months that Victoria's statewide 14 day average has increased

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    Virus that causes Covid-19 can survive up to 28 days on surfaces, scientists find

    Researchers find Sars-CoV-2 survives longer at lower temperatures and lasts 10 days longer than influenza on some surfaces

    Australian scientists have found that the virus that causes Covid-19 can survive for up to 28 days on surfaces such as the glass on mobile phones, stainless steel, vinyl and paper banknotes.

    The national science agency, the CSIRO, said the research undertaken at the Australian Centre for Disease Preparedness (ACDP) in Geelong also found that Sars-CoV-2 survived longer at lower temperatures.

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    Meghan: ‘I’m told I was the most trolled person in the world’

    Duchess of Sussex speaks of ‘almost unsurvivable’ online abuse she has experienced

    The Duchess of Sussex has revealed she was told last year that she was the “most trolled person in the entire world” in a podcast in which she opened up about the “almost unsurvivable” online abuse she has experienced.

    Meghan and her husband, Prince Harry, joined three Californian high school students during an episode of their podcast, Teenager Therapy, and discussed topics including mental health stigma, self-care and online abuse.

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    Cleaning up: the social media stars making housework cool

    Donning the Marigolds need not be a chore, according to a new breed of influencers who say cleaning is fun and aspirational

    There were fears that this autumn’s bumper crop of books would see some titles overlooked – but one volume definitely didn’t get brushed under the carpet. This Is Me by Sophie Hinchliffe, better known as the Instagram cleaning sensation Mrs Hinch, was the runaway hit of Super Thursday on 1 October, fighting stiff competition from almost 800 other hardbacks published that day to top the UK charts and shift more than 90,000 copies in its first week.

    It’s no surprise: Mrs Hinch’s three previous books have been bestsellers, and the 30-year-old comes with a readymade audience thanks to her “Hinch Army” of 3.8 million Instagram followers.

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    Northern cities seek overhaul of national tracing ‘shambles’

    Local health teams are outperforming the NHS Covid contact system, but as cases rise they want a rethink

    Under the grandeur of Preston market’s Victorian canopy, the nervousness wrought by a resurgence of Covid-19 is not far away. Amid the fruit, veg and dairy stalls, all the shoppers and stallholders are wearing masks, keeping their distance. “Everybody seems to be sticking to the rules as much as they can,” said Gary Quinn, the landlord of the Orchard pub. “People haven’t been very clear on what is allowed, but I haven’t seen people acting maliciously. People are trying their best.”

    Despite the efforts, the city is again seeing a resurgence of the virus, with 324 cases per 100,000 in the past seven days. Like dozens of other local authorities around the country, Preston city council is not solely relying on the national test and trace system to help track the virus. It has taken matters into its own hands, setting up walk-in test sites and its own tracing system. Its team has received 300 local contacts a week, with council staff making home visits to more than 100 people who needed to self-isolate and could not be contacted by any other means.

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    The race for a Covid vaccine: inside the Australian lab working round the clock to produce 100m doses

    The Guardian is given a unique insight into the operations of CSL, which is making vaccines that could help end the crisis

    Some call it the “happy soup”.

    Take a dash of modified Covid-19 protein DNA, mix it with cells from a Chinese hamster’s ovary, and place the combination in two state-of-the-art 2,000L bioreactors in a sprawling scientific facility on Melbourne’s northern fringes.

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    NSW Covid hotspots: list of Sydney and regional case locations

    Here are the current coronavirus hotspots in New South Wales and what to do if you’ve visited them

    New South Wales health authorities have released a list of hotspots where Covid-positive people have visited while infectious.

    Those who attended some locations must isolate immediately for 14 days, others must monitor for symptoms.

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