‘I’m scared I’ve left it too late to have kids’: the men haunted by their biological clocks

It’s certainly not just women who worry about ageing and procreation – and now men have begun speaking about their own deep anxieties

It was when Connor woke up in the middle of the night to go to the bathroom that he started thinking about it. The 38-year-old civil servant from London got back into bed and couldn’t sleep: he was spiralling. “I thought: ‘Shit, I might not be able to have children. It actually might not happen,’” he says.

“It started with me thinking about how I’m looking to buy a house, and everything is happening too late in my life,” Connor says. “Then I started worrying about how long it would take me to save again to get married, after I buy the house. I was doing the maths on that – when will I be able to afford to be married, own a house and start having kids? Probably in my 40s. Then I started freaking out about what the quality of my sperm will be like by then. What if something’s wrong with the child? And then I thought, oh no, what if me and my girlfriend don’t work out? I’ll be in an even worse scenario in a few years.”

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The last great mystery of the mind: meet the people who have unusual – or non-existent – inner voices

Does your internal monologue play out on a television, in an attic, as a bickering Italian couple – or is it entirely, blissfully silent?

Claudia*, a sailor from Lichfield in her late 30s, is not Italian. She has never been to Italy. She has no Italian family or friends. And she has no idea why a belligerent Italian couple have taken over her inner voice, duking it out in Claudia’s brain while she sits back and listens.

“I have no idea where this has come from,” says Claudia, apologetically. “It’s probably offensive to Italians.” The couple are like the family in the Dolmio pasta sauce adverts: flamboyant, portly, prone to waving their hands and shouting. If Claudia has a big decision to make in her life, the Italians take over.

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Unfreezing the ice age: the truth about humanity’s deep past

Archaeological discoveries are shattering scholars’ long-held beliefs about how the earliest humans organised their societies – and hint at possibilities for our own

In some ways, accounts of “human origins” play a similar role for us today as myth did for ancient Greeks or Polynesians. This is not to cast aspersions on the scientific rigour or value of these accounts. It is simply to observe that the two fulfil somewhat similar functions. If we think on a scale of, say, the last 3m years, there actually was a time when someone, after all, did have to light a fire, cook a meal or perform a marriage ceremony for the first time. We know these things happened. Still, we really don’t know how. It is very difficult to resist the temptation to make up stories about what might have happened: stories which necessarily reflect our own fears, desires, obsessions and concerns. As a result, such distant times can become a vast canvas for the working out of our collective fantasies.

Let’s take just one example. Back in the 1980s, there was a great deal of buzz about a “mitochondrial Eve”, the putative common ancestor of our entire species. Granted, no one was claiming to have actually found the physical remains of such an ancestor, but DNA sequencing demonstrated that such an Eve must have existed, perhaps as recently as 120,000 years ago. And while no one imagined we’d ever find Eve herself, the discovery of a variety of other fossil skulls rescued from the Great Rift Valley in east Africa seemed to provide a suggestion as to what Eve might have looked like and where she might have lived. While scientists continued debating the ins and outs, popular magazines were soon carrying stories about a modern counterpart to the Garden of Eden, the original incubator of humanity, the savanna-womb that gave life to us all.

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Viva la vulva: why we need to talk about women’s genitalia

Ignorance about the basic biology of vulvas is still shockingly high – yet there are huge health benefits, physical and emotional, to be won with better understanding

If you have a vulva between your legs, could you identify the seven separate structures in a mirror? If your partner has a vulva, can you identify theirs?

For over half the population, the vulva is a significant part of their body; an exit and an entrance, a site of pleasure and, often, pain, that speaks to core human function and need. In 2021, it can feel as if we’re on the cliff-edge of emancipation from the history of oppression and ick surrounding female genitalia. The booming sex toy market, a growing awareness of hormonal cycles and the messy reality of periods, a sharper focus on female pleasure and evolving conversations about menopause all point to real progress. Yet there remains a well of misunderstanding in society about what’s down there (clitoris, labia majora, labia minora, urethral opening, vaginal opening, perineum and anus, by the way), with tangible consequences.

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‘Sophisticated’: ancient faeces shows humans enjoyed beer and blue cheese 2,700 years ago

Austrian Alps salt miners had a ‘balanced diet’, with an analysis of bronze and iron age excrement finding the earliest evidence of cheese ripening in Europe

It’s no secret that beer and blue cheese go hand in hand – but a new study reveals how deep their roots run in Europe, where workers at a salt mine in Austria were gorging on both up to 2,700 years ago.

Scientists made the discovery by analysing samples of human excrement found at the heart of the Hallstatt mine in the Austrian Alps.

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Local Covid vaccines fill gap as UN Covax scheme misses target

India, Egypt and Cuba among first states to develop and make their own vaccines as Covax falls behind

Developing countries are increasingly turning to homegrown Covid vaccinations as the UN-backed Covax programme falls behind.

While western countries roll out booster jabs to their own populations, Covax, which was set up by UN agencies, governments and donors to ensure fair access to Covid-19 vaccines for low- and middle-income countries, has said it will miss its target to distribute 2bn doses globally by the end of this year.

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Capsule of 1765 air reveals ancient histories hidden under Antarctic ice

Polar Zero exhibition in Glasgow features sculpture encasing air extracted from start of Industrial Revolution

An ampoule of Antarctic air from the year 1765 forms the centrepiece of a new exhibition that reveals the hidden histories contained in polar ice to visitors attending the Cop26 climate conference in Glasgow.

The artist Wayne Binitie has spent the past five years undertaking an extraordinary collaboration with scientists of the British Antarctic Survey (BAS), who drill, analyse and preserve cylinders of ice from deep in the ice sheet that record past climate change.

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Covid by numbers: 10 key lessons separating fact from fiction

To make sense of coronavirus data, the Observer asked David Spiegelhalter and Anthony Masters of the Royal Statistical Society Covid taskforce to write a column. That column has now inspired a book. Here are some of its insights

Genomic sequencing has identified more than 1,000 different seeds of Sars-CoV-2 introduced in early 2020. Instead of one central outbreak, reverberating outwards like an explosion, we now know there were many erupting simultaneously across the country. There were far more imports of Sars-CoV-2 from France, Italy and Spain than from China – viruses can take indirect flights. The peak was early March, after the school half-term, but a popular holiday time for adults. At the Champions League football match at Anfield between Liverpool and Atlético Madrid on 10 March, 49,000 local supporters mixed with 3,000 fans of the opposing team, while schools in Madrid were shut and supporters could not attend matches. To add insult to injury, Liverpool lost 3–2, and 4–2 on aggregate.

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Woman successfully treated for depression with electrical brain implant

‘Stunning’ neuroscientific advance gives hope to those with mental illness not helped with drugs

A woman with severe depression has been successfully treated with an experimental brain implant in a “stunning” advance that offers hope to those with intractable mental illness.

The device works by detecting patterns of brain activity linked to depression and automatically interrupting them using tiny pulses of electrical stimulation delivered deep inside the brain.

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Covid antiviral pill halves hospitalisations and deaths, maker says

If approved, Merck’s drug would be first simple oral medication shown to be effective against coronavirus

An antiviral pill was found to reduce hospitalisations and deaths by half in patients newly diagnosed with Covid-19, according to results announced on Friday.

If approved, the drug made by the US firm Merck and Ridgeback Biotherapeutics would be the first simple oral medication shown to be effective against Covid-19, which would mark a crucial advance in the fight against the pandemic. Other drugs, such as remdesivir, have been shown to be effective if given early, but all currently approved treatments need to be given as injections or IV infusions.

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Dutch scientists may have solved mystery of why some twins are identical

Discovery of DNA modifications raises hope of treatment for disorders that particularly afflict twins

The medical mystery of what causes some twins to be born identical may have been solved by scientists in the Netherlands, raising hopes for treatment of congenital disorders that disproportionately afflict them.

Identical twins form after a fertilised egg, called a zygote, splits into two embryos sharing exactly the same genes. The reason for the split is unknown.

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Gibraltar cave chamber discovery could shed light on Neanderthals’ culture

Researchers find space in Gorham’s Cave complex that has been closed off for at least 40,000 years

Researchers excavating a cave network on the Rock of Gibraltar have discovered a new chamber, sealed off from the world for at least 40,000 years, that could shed light on the culture and customs of the Neanderthals who occupied the area for a thousand centuries.

In 2012, experts began examining Vanguard Cave, part of the Gorham’s Cave complex, to determine its true dimensions and to see whether it contained passages and chambers that had been plugged by sand.

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Could whistling shed light on the origins of speech?

Whistled languages exist on every inhabited continent – now some scientists think similar dialects could have preceded the spoken word

For centuries, shepherds from the small village of Aas in the French Pyrenees led their sheep and cattle up to mountain pastures for the summer months. To ease the solitude, they would communicate with each other or with the village below in a whistled form of the local Gascon dialect, transmitting and receiving information accurately over distances of up to 10 kilometres.

They “spoke” in simple phrases – “What’s the time?”, “Come and eat,”, “Bring the sheep home” – but each word and syllable was articulated as in speech. Outsiders often mistook the whistling for simple signalling (“I’m over here!”), and the irony, says linguist and bioacoustician Julien Meyer of Grenoble Alpes University in France, is that the world of academia only realised its oversight around the middle of the 20th century, just as the whistled language of Aas was dying on the lips of its last speakers.

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Human footprints thought to be oldest in North America discovered

Ancient tracks found in New Mexico are believed to be between 21,000 and 23,000 years old, study says

New scientific research conducted by archaeologists has uncovered what they believe are the oldest known human footprints in North America.

Research done at the White Sands national park in New Mexico discovered the ancient footprints, with researchers estimating that the tracks were between 21,000 and 23,000 years old, reported Science.

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Readers reply: why do humans cry when they are sad?

The long-running series in which readers answer other readers’ questions on subjects ranging from trivial flights of fancy to profound scientific and philosophical concepts

I understand that tears flush away foreign objects from the eye. But what advantage does crying have when one is feeling sad (or happy)? Perhaps it is to signal an extreme of emotion, but then why would a solitary sad person cry when there was no one around? David Dobbs

Send new questions to nq@theguardian.com.

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Why does world’s tallest populace seem to be getting shorter?

Dutch people born in 2001 are not as tall as previous generation – is it genetics, migration or nutrition?

From brutal conflicts to periods of prosperity, pandemics to triumphs for equality, human history is full of highs and lows. But such fluctuations don’t just affect society: the human body can also be a sign of the times.

Studies have shown that our height is not just a matter of genetics but is also influenced by the environment we live in, with key factors including our nutrition and experience of sickness, such as diarrhoea.

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‘The virus is painfully real’: vaccine hesitant people are dying – and their loved ones want the world to listen

In the UK, the majority of those now in hospital with Covid-19 are unvaccinated. Many face their last days with enormous regret, and their relatives are telling their stories to try to convince others like them

Matt Wynter, a 42-year-old music agent from Leek, Staffordshire, was working out in his local gym in mid-August when he saw, to his great surprise, that his best friend, Marcus Birks, was on the television. He jumped off the elliptical trainer and listened carefully.

The first thing he noticed was that Birks, who was also from Leek and a performer with the dance group Cappella, looked terrible. He was gasping for breath and his face was pale. “Marcus would never usually have gone on TV without having done his hair and had a shave,” Wynter says.

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Firm raises $15m to bring back woolly mammoth from extinction

Scientists set initial sights on creating elephant-mammoth hybrid, with first calves expected in six years

Ten thousand years after woolly mammoths vanished from the face of the Earth, scientists are embarking on an ambitious project to bring the beasts back to the Arctic tundra.

The prospect of recreating mammoths and returning them to the wild has been discussed – seriously at times – for more than a decade, but on Monday researchers announced fresh funding they believe could make their dream a reality.

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‘A very cruel exit’: UK’s aid cuts risk rapid return of treatable diseases

£200m project to eliminate avoidable blindness and disfigurement in Africa ends after funding is prematurely axed

A chandelier sparkling in the background, the grandeur of Downing Street gleaming behind him, Boris Johnson looks into the camera and speaks with solemnity. He is marking World Neglected Tropical Diseases Day, he says, to raise awareness of these “terrible afflictions … which impose an immense burden of suffering in developing countries”.

Huge progress has been made, he says, in the fight against the diseases, not least as a result of British aid to some of the poorest parts of the world. But there is more – much more – to be done: more than a billion people are still at risk, he warns, and that is why the UK “fully supports” the World Health Organization’s big elimination push over the next decade.

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Kathryn Paige Harden: ‘Studies have found genetic variants that correlate with going further in school’

The behaviour geneticist explains how biology could have an influence on academic attainment – and why she takes an anti-eugenics approach

Kathryn Paige Harden argues how far we go in formal education – and the huge knock-on effects that has on our income, employment and health – is in part down to our genes. Harden is a professor of psychology at the University of Texas at Austin, where she leads a lab using genetic methods to study the roots of social inequality. Her provocative new book is The Genetic Lottery: Why DNA Matters for Social Equality.

To even talk about whether there might be a genetic element to educational attainment and social inequality breaks a huge social taboo – particularly on the political left, which is where you say your own sympathies lie. The spectre of eugenics looms large, and no one wants to create a honeypot for racists and classists. To be clear, it is scientifically baseless to make any claims about differences between racial groups, including intelligence, and you are not doing that. But why go here?
I wrote this book first for my fellow scientists, who haven’t necessarily seen the relevance of genetics for their own work or have been afraid to incorporate it because of these associations. There is a large body of scientific knowledge being ignored lest the eugenics genie be let out of the bottle.

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