Category Archives: Cancer

Living in a woman’s body: I want my daughter to be inspired by my miraculous scars

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When I was pregnant, I discovered that I had developed breast cancer – just like my mother before me. One day, the child I was carrying may face the same hard choices

When I was five, I would talk to my mother while she was in the bath. When she stood to get out, the water fell from her, her skin pink from the heat. Her body was miraculous to me. Women’s bodies are miraculous, with the things they can do, but I didn’t know any of that then. I just knew that she was soft and perfect, and mine.

By the time my mother developed breast cancer, I was 30. She was double that age and there was an ocean between us: I was married and living in New York, so when the news came, I couldn’t hold her to me, or be a practical support. I sat on my bed and cried. The next time I saw her, it was all over. One breast removed and carefully reconstructed. The cancer gone. My husband asked me, as we approached my parents in the airport, whether it was OK to give my mum a hug. The surgery was recent; I wasn’t sure. But it was OK. She seemed the same.

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Delayed diagnoses and self-imposed lockdown: Australians living with cancer during Covid

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Two years of the pandemic have meant drops in essential screening and detection, while cancer patients undergo treatments alone and isolate to avoid Covid risks

When Claire Simpson turned 50 in early 2020, she received a letter telling her to get a mammogram. Then the pandemic hit, and Victoria went into lockdown.

“Like many people, I put it off until we were coming out of that lockdown, but by then it was September and I couldn’t get an appointment until December,” she says.

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How DNA link could unlock mystery of cancer patients ‘wasting away’

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New research into sudden weight loss finds a possible cause of cachexia in cancer patients and Cockayne syndrome in children

One of the most serious impacts of cancer is the sudden loss of weight, appetite, and muscle that can hit some patients in the later stages of the disease. This wasting syndrome is known as cachexia and it can be triggered in other serious conditions, including heart disease and HIV.

In addition, an inherited version of extreme wasting syndromes can affect children. Known as Cockayne syndrome, it causes them to suffer severe malnutrition and wasting that parallels the effect of cachexia.

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A new start after 60: ‘I’m one of the world’s worst athletes – but I learned to skate in my 70s’

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Richard Epstein, a 78-year-old scientist with stage four prostate cancer, says that skating helps him to embrace uncertainty

The first time Richard Epstein went to his local ice-skating rink in Santa Fe, New Mexico, he was handed a free pair of skates. They had been left behind by a discontented customer. “I do things out of my comfort zone, and good things happen,” he observes.

This wisdom was borne out last December, when Epstein, now 78, skated in his first exhibition. His wife filmed his routine, which he performed with his coach, Teri Moellenberg, then his eldest daughter posted it on Twitter, along with a note that Epstein has stage four prostate cancer. Nearly 3 million people viewed it. Epstein is somewhat baffled by the response, describing himself as “just an old guy going around in circles”.

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First patients of pioneering CAR T-cell therapy ‘cured of cancer’

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Cancer-killing cells still present 10 years on, with results suggesting therapy is a cure for certain blood cancers

Two of the first human patients to be treated with a revolutionary therapy that engineers immune cells to target specific types of cancer still possess cancer-killing cells a decade later with no sign of their illness returning.

The finding suggests CAR T-cell therapy constitutes a “cure” for certain blood cancers, although adapting it to treat solid tumours is proving more challenging.

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Scientists developing single test to detect risk of four cancers in women

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Experts may be able to predict risk of developing ovarian, breast, womb and cervical cancers using cells from routine smear test

Scientists are developing a “revolutionary” test to predict a woman’s risk of four cancers using a single sample collected during cervical screening.

Using cervical cells from a routine smear test, experts may be able to spot ovarian and breast cancer or predict their likelihood of developing, according to two papers published in the journal Nature Communications. Further results are due on the ability of the WID-test – women’s cancer risk identification – to predict womb and cervical cancer, researchers said.

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‘More people will die’: fears for clinically vulnerable as England axes plan B

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Coronavirus pandemic’s finishing line has not yet come clearly into focus for millions of people

“We must learn to live with Covid in the same way we have to live with flu,” Sajid Javid told the nation this week. For most people, the parallel with flu is now valid: vaccinations and acquired immunity have defanged Covid to the point that there is no longer much risk of becoming severely unwell.

However, the pandemic’s finishing line has not yet come clearly into focus for a sizeable minority in society. In England, 3.7 million people fall in the clinically extremely vulnerable (CEV) category, including those with blood cancers, an organ transplant, kidney disease and other conditions linked to immunosuppression.

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Tennis great Chris Evert having treatment for ovarian cancer

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Winner of 18 grand slam singles titles says she feels incredibly fortunate that the cancer was caught before it spread

Tennis great Chris Evert has been diagnosed with ovarian cancer and is undergoing treatment.

The 18-time grand slam singles champion said the diagnosis came in early December following a preventive hysterectomy after she had been informed she was at risk of cancer.

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Super poo: the emerging science of stool transplants and designer gut bacteria

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As more people turn to faecal transplants for their health benefits, researchers in Adelaide are harnessing the power of high-quality poo in new treatments that can simply be swallowed

Good poo donors are so hard to find they’re sometimes called “unicorns”. These elusive, healthy creatures service a market for faecal transplants that is growing rapidly as evidence of its benefits mounts.

Emerging science shows that a human’s microbiome – their constellation of gut microbes – has a far greater effect on health than anyone previously imagined. This enormous ecosystem we host in our bodies includes bacteria, fungi, viruses and more.

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The person who got me through 2021: Heather Phillipson’s sculpture brightened my trips to hospital

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On my way to have painful medical tests, I felt dejected. Then I saw a giant dollop of whipped cream with a cherry on top in Trafalgar Square

Most people were keen to leave 2020 behind but had I known what was coming in 2021, I might have chosen to stay there. From the first days of January I started to experience extended bouts of dizziness – a feeling that the ground was moving beneath me, with bursts of tinnitus, nausea and head pressure thrown in.

One thing I can tell you about near constant dizziness is that it’s not the ideal state to be in if you are trying to homeschool a four-year-old, entertain a stir-crazy one-year-old and hold down a full-time job. As for fun activities: just looking at a playground roundabout was enough to send me spinning out.

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Science YouTuber Philipp Dettmer: ‘Getting cancer was super-interesting’

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The online star with 15 million subscribers on demystifying everything from black holes to the immune system, the trouble with anti-vaxxers, and what his cancer taught him

Skim Philipp Dettmer’s CV and you’d have to say he was an improbable candidate to become one of the world’s foremost science communicators. The 35-year-old from Munich dropped out of high school in Germany aged 15. He eventually did a history degree, and only became involved in science through his interest in infographics. This led, in 2013, to him creating Kurzgesagt (AKA “In a nutshell”), one of the most popular science channels on YouTube. The platform’s irreverent, kaleidoscopic videos – stripped-back guides to everything from black holes to Covid – have more than 15 million subscribers and have clocked up almost 1.5bn views.

Dettmer has now written a book about the human immune system, which has intrigued him for more than a decade. Everyone has an opinion on theirs – whether it’s good or not up to much; how best to “boost” it – but it can be a struggle to understand how it works. In Immune: A Journey into the Mysterious System That Keeps You Alive, Dettmer uses eye-catching graphics and simple language to untangle the strange, compelling, sometimes grisly methods our bodies use to defend us from disease.

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Flu, cancer, HIV: after Covid success, what next for mRNA vaccines?

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The technology was viewed with scepticism before the pandemic but there is now growing confidence about its use

It is one of the most remarkable success stories of the pandemic: the unproven technology that delivered the Moderna and Pfizer/BioNTech vaccines in record time, helping to turn the tide on Covid-19. The vaccines are based on mRNA, the molecule that instructs our cells to make specific proteins. By injecting synthetic mRNA, our cells are turned into on-demand vaccine factories, pumping out any protein we want our immune system to learn to recognise and destroy.

Pre-pandemic, the technology was viewed with scepticism – a clever concept, but not guaranteed to deliver. Now there is growing confidence that mRNA vaccines could have far-reaching applications in tackling diseases from flu to malaria.

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How not being able to cuddle my sick baby led to a life-saving invention

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Caitlin Shorricks’s design for a special vest to protect her daughter during cancer treatment is now helping families across the country

Caitlin Shorricks will never forget the agony of seeing her three-month-old baby, Theía, being treated for cancer last year. She was scared to pick up her daughter for fear of accidentally pulling out the tube running into her main jugular vein: “I was totally terrified. If I wanted to hold her, I had to call a nurse to help.”

Determined to find a safe way to cuddle her little girl, she teamed up with her aunt Eva Newberry, who used to be a dressmaker, to create a garment for the baby that would keep the line safely tucked away in a pocket. They called it a “Choob Toob’”.

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New treatment destroys head and neck cancer tumours in trial

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Exclusive: combination of drugs causes tumours to vanish in some terminally ill patients, study finds

A new cancer treatment can wipe out tumours in terminally ill head and neck cancer patients, scientists have discovered.

In a landmark trial, a cocktail of immunotherapy medications harnessed patients’ immune systems to kill their own cancer cells and prompted “a positive trend in survival”, according to researchers at the Institute of Cancer Research (ICR), London, and the Royal Marsden NHS foundation trust.

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‘Highly effective’ ovarian cancer treatment could help thousands of women

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New drug combination shrunk tumours significantly in 46% of patients with treatment-resistant form of disease

Thousands of women with ovarian cancer could benefit from a revolutionary drug combination after it was shown to shrink tumours in half of patients with an advanced form of the disease.

The pair of drugs – which work together to block the signals cancer cells need to grow – could offer a new treatment option for women with a type of ovarian cancer that rarely responds to chemotherapy or hormone therapy.

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Number of young smokers rose by a quarter in first lockdown, England study shows

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Stress of pandemic could be behind increase in people aged 18-34, but number who quit habit also rose

The number of young adults who smoke in England rose by about a quarter in the first lockdown, research has suggested.

Nevertheless, the number of people who stopped smoking altogether increased, with the number across all age groups almost doubling during the first national lockdown when compared with the period immediately prior, researchers from University College London (UCL) and the University of Sheffield said.

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Alcohol linked to more cancers than thought, study finds

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Imperial College London researchers also find that drinking coffee protects against liver cancer

Consuming alcohol increases the risk of getting more cancers than previously thought, according to a major study, which also found that drinking coffee protects against liver cancer.

Alcohol consumption is linked to several cancers including those of the head and neck – mouth, pharynx and larynx – oesophageal and bowel, along with the more widely known connection with breast and liver cancer, according to an international team led by Imperial College London.

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Trial to test if cannabis-based mouth spray can treat brain tumours

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First such study in the world aims to find out if Sativex combined with chemotherapy can help treat glioblastoma

Cancer charities and the NHS are preparing to investigate whether a cannabis-based mouth spray can treat brain tumours and help patients to live longer.

Doctors will give patients across the UK with a recurrent brain tumour called a glioblastoma the drug, which is known as Sativex, alongside a chemotherapy medication – temozolomide – in a clinical trial in an attempt to kill off cancerous cells.

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Is medical cannabis really a magic bullet?

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Research increasingly suggests that extracts from the plant are effective in treating pain, anxiety, epilepsy and more, but experts still preach caution around recreational use

In 2017, Mikael Sodergren, a liver and pancreatic cancer surgeon at Imperial College healthcare NHS trust, was finding himself becoming increasingly interested in the potential role of medical cannabis in treating pain, especially the discomfort experienced by patients after complex operations.

“I hope that I do a lot of good, but unfortunately in the short term, I inflict a lot of pain with cancer surgery,” says Sodergren. “So we’re reliant on pretty nasty painkillers, such as high-strength intravenous opioids, which we’re trying to move away from. They slow patients down and they cause complications.”

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Alcohol caused 740,000 cancer cases globally last year – study

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Researchers behind estimate say more needs to be done to raise public awareness of link

Alcohol is estimated to have caused more than 740,000 cancer cases around the world last year, and experts say more needs to be done to highlight the link.

There is strong evidence that alcohol consumption can cause various cancers including those of the breast, liver, colon, rectum, oropharynx, larynx and oesophagus. Research suggests that even low levels of drinking can increase the risk.

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