How effective is the Novavax Covid vaccine and will it work against variants?

Everything you need to know about the trial results for a new coronavirus vaccine

In an interim analysis of a phase 3 clinical trial conducted in the UK, the vaccine has shown 89% efficacy, with 27% of participants in the trial – almost 4,000 people – older than 65. That trial suggested 95.6% efficacy against the original coronavirus and 85.6% efficacy against the more recent UK strain. Those results were based on the first 62 cases of Covid-19 identified among volunteers, with 56 cases among those given a placebo against just six in those given the vaccine.

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Novavax Covid vaccine nearly 90% effective in UK trial – video

Another Covid vaccine, trialled in the UK and bought by the government, has been shown to be nearly 90% effective and work against the UK and South African variants of the virus.

Stanley Erck, CEO of Novavax, has said numbers show 'dramatic demonstrations' of the new vaccine's ability to develop an immune response against different strains of Covid-19.

The UK vaccines taskforce has bought 60m doses of the Novavax vaccine which will be manufactured on Teesside in the UK

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Slavery survivors moved ‘without notice, without reason’ in London lockdown

Despite stay at home orders, vulnerable asylum seekers in Home Office accommodation say they were given as little as a day’s notice

Modern slavery survivors with young children were among refugees allegedly forced to move accommodation in London with as little as one day’s notice during coronavirus lockdowns this winter.

Women who are among the UK’s most vulnerable refugees and asylum seekers said they were given just 24 hours to pack before being moved from accommodation provided by the Home Office, often having to travel long distances across the capital, in late December and January.

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Man arrested over abusive comments to staff in Covid hospital ward

Man, 45, from Kent, arrested after a video of a group of people trying to remove patient was posted online

A 45-year-old man has been arrested after a group of people became abusive to hospital staff when they attempted to remove a Covid-19 patient.

The man, of Maidstone, Kent, has been arrested on suspicion of causing a public nuisance and is in custody, said Surrey police.

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EU could block millions of Covid vaccine doses from entering UK

European commission says new mechanism will give national regulators power to refuse exports

Millions of doses of coronavirus vaccine could be blocked from entering Britain from the EU within days after Brussels said it had to respond to shortages emerging in member states.

Following reports of a lack of doses across the bloc, the European commission announced plans to give national regulators the power to reject export requests. The development raises concerns over the continued flow of the Pfizer/BioNTech vaccine, for which the UK has a 40m-dose order, from its plant in Belgium.

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WHO team exits Wuhan quarantine to start Covid fact-finding mission

Mission is politically charged as China seeks to avoid blame for alleged missteps in outbreak response

An international team of World Health Organization experts has emerged from quarantine in the Chinese city of Wuhan, to begin much-delayed fieldwork into the origins of the Sars-CoV-2 virus that caused the Covid-19 pandemic.

The fact-finding mission has been beset by controversy after the WHO accused China of dragging its heels over arrangements. The team arrived more than a year after doctors in the city first raised the alarm about a mystery new illness spreading among their patients.

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GameStop shares plunge after ban by Robinhood app

Meteoric rise fizzles out after small investors are barred from trading in groups that had soared in value

Small investors mounting an assault on Wall Street speculators suffered a setback on Thursday as trading platforms banned them from buying more shares in GameStop, spawning conspiracy theories, political intervention and at least one lawsuit.

Amateur trading app Robinhood stopped users from investing any further in GameStop – a US chain of video games stores – and seven other companies on Thursday, after an extraordinary rise in their value, spurred by users of the chat forum website Reddit, that cost some hedge funds billions of dollars.

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‘A bit like The Great Escape’: activists hold out in Euston tunnel

HS2 protesters describe how they built tunnel, as officials warn of danger from gas and water pipes

Environmental activists have held out for their second night in the Euston tunnel, but eviction officers have said the tunnel is close to gas and water pipes and that the activists are putting their own lives at risk.

The tunnellers described how they constructed what is thought to be one of the largest tunnel networks to be occupied by protesters in one of the busiest parts of London without being detected.

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How UK spent £800m on controversial Covid tests for Dominic Cummings scheme

US firm Innova believed to be largest beneficiary of contracts after selling millions of Covid tests that are dividing opinion

Dominic Cummings’ plan to test millions of people a day for coronavirus led the government to spend over £800m on quick turnaround tests that were later found in a pilot to give the wrong results as much as 60% of the time, the Guardian can reveal.

Operation Moonshot, a mass testing scheme championed by the prime minister’s former chief adviser, prompted the government to buy huge numbers of so-called lateral flow tests from a company owned by a little-known US private equity house.

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Doe-eyed Kristen Stewart might just take the crown as Princess Diana

In a highly competitive field, the American actor has perfected the put-upon princess look for Spencer, the latest royal biopic

Some films have to work harder than others to get bums on seats. Some can charm audiences with big stars, or the lure of a continuing franchise, or the promise of a scene where King Kong takes a swing at Godzilla like he’s half-cut in a Wetherspoons car park. And then, right at the other end of the scale, is Spencer.

Make no mistake, Spencer will have to be brilliant to make people go and see it. Better than brilliant, even. It will have to be the perfect movie; entertaining and fun and moving and so technically accomplished that film historians will come to view it as the moment that cinema entered a new epoch. Anything less than that and Spencer is done for.

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‘They said I wasn’t hot enough’: Carey Mulligan hits out again at magazine review

Variety review of black comedy Promising Young Woman prompts actor to speak out on industry’s institutionalised sexism

Carey Mulligan has said she was alarmed after a major publication ran a review of her new film questioning whether she was attractive enough for the role.

Related: Variety's apology to Carey Mulligan shows that the critic's ivory tower is toppling | Peter Bradshaw

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Mining giant Glencore faces human rights complaint over toxic spill in Chad

Dozens of villagers, including children, claim they suffered severe burns and sickness after contact with contaminated water

The UK government has accepted a human rights complaint against mining and commodities giant Glencore regarding a toxic wastewater spill in Chad, where dozens of villagers – among them children – claim they suffered severe burns, skin lesions and sickness after contact with contaminated water.

The complaint, brought by three human rights groups on behalf of affected communities, alleges environmental abuses and social engagement failures by the FTSE-100 company in relation to two spillages, the wastewater spill and an alleged oil spill, both in 2018.

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Government lawyer tells court M15 officers could authorise murder

Admission came hours before bill allowing continuation of controversial powers passed the Commons

Government lawyers have told a court that MI5 officers could authorise an informer to carry out a murder under controversial powers that ministers want to see continued contained in a bill that passed the Commons hours later.

The admission came in a court of appeal hearing on Wednesday when Sir James Eadie, representing the government, was asked if there was “a power for a Security Service officer to authorise an agent to execute an extremely hostile individual”.

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How quarantine rules work and what UK government is planning

Analysis: Arrivals from high-risk countries will have to pay to isolate in a hotel under Boris Johnson’s proposals

With new hotel quarantine measures for international arrivals from high-risk countries due to be introduced to curb the spread of Covid-19, focus falls on how they will work.

Here, we look at what the rules are now and what’s being done by the UK government to toughen border controls.

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Boris Johnson ‘hopeful’ schools will reopen on 8 March – video

Boris Johnson has said that 8 March is the earliest schools could reopen, but warned the date depended on ‘lots of things going right’. A firm decision will be taken in the week of 22 February after reviewing infection and vaccination data, the prime minister said

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Britain and EU clash over claims to UK-produced Covid vaccine

EU health commissioner dismisses AstraZeneca argument it is contractually obliged to supply UK first

Britain is on a collision course with the European Union over vaccine shortages after Brussels refused to accept that people in the UK have first claim on Oxford/AstraZeneca doses produced in local plants.

The EU’s health commissioner outright dismissed on Wednesday an argument made by Pascal Soriot, the Anglo-Swedish company’s chief executive, that he was contractually obliged to supply the UK first.

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Sturgeon questions whether Johnson’s trip to Scotland ‘essential’

First minister also says UK government’s hotel quarantine plans ‘do not go far enough’

Nicola Sturgeon has questioned whether Boris Johnson’s planned trip from London to Scotland on Thursday is “genuinely essential”, suggesting his visit makes it harder to convince the public to stick to travel restrictions.

At her daily briefing, when she also warned that the UK government’s hotel quarantine plan for travellers “does not go far enough”, Scotland’s first minister said that while she was sure the prime minister and his advisers would take care to make sure no laws were broken, “we all have to make judgments on what we genuinely think is essential”.

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Boeing 737 Max cleared to fly again by EU regulator

The UK’s Civil Aviation Authority will certify the plane separately

Boeing’s 737 Max aircraft has been given the green light to return to the skies in the EU by the European Union Aviation Safety Agency (EASA), after a 22-month grounding following two fatal crashes.

Marking a crucial step in its return to service, a modified version of the US company’s previously bestselling aeroplane has been given permission to fly again, although not until a package of checks and training is completed.

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‘I’m flabbergasted’: Monique Roffey on women, whiteness and winning the Costa

The Mermaid of Black Conch’s author explains why she expected ‘a quiet life’ for the formally daring, magical realist novel that has been declared book of the year

After two decades of splashing around in the shallows of success, Monique Roffey was taking no chances with The Mermaid of Black Conch. The novel, which won the Costa book of the year award on Tuesday, is written in a Creole English and uses a patchwork of forms, from poetry to journal entries and an omniscient narrator, and “employs magical realism to the max”. Even its title was against it, she realised. “You’re either going to read a novel about a mermaid or you aren’t.”

Any one of these, she says, would scare away most publishers. So when one, the independent Peepal Tree Press, did bite, she launched a crowdfunder to enable her to hire her own publicist. It’s a mark of the esteem in which the 55-year-old author and university lecturer is held by those familiar with her work that 116 people chipped in, raising £4,500 within a month. Then, two weeks before the novel was due to be published, the UK went into lockdown, shutting bookshops and forcing the cancellation of a tour that was particularly important for a writer who has always swum between two continents and two cultures.

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Here are five ways the government could have avoided 100,000 Covid deaths | Devi Sridhar

The UK needs to learn from the lessons of the past year and come up with a concrete plan to avert a disastrous third wave

Yesterday Britain passed a grim milestone. A further 1,631 deaths from Covid-19 were recorded, taking the official tally above 100,000, though data from the Office for National Statistics suggests the total number will now be nearer 120,000. In a briefing, Boris Johnson has said his government did everything it could to minimise the loss of life, but these deaths were far from inevitable. While the number of UK deaths has entered the hundreds of thousands, New Zealand has recorded only 25 deaths from Covid-19 so far. Taiwan has recorded seven, Australia 909, Finland 655, Norway 550 and Singapore 29. These countries have largely returned to normal daily life.

In the first year of the pandemic, the UK faced three big challenges. Our national government had no long-term strategy for suppressing the virus beyond a continual cycle of lockdowns. Even now we still don’t know what the government’s plans for the next six months are. In the early days of the pandemic, the UK treated Covid-19 like a bad flu. The government halted testing, and the initial plan seemed to be allow the virus to run unchecked through the population (the “herd immunity” approach). Finally, ministers have pitted the economy against public health, instead of realising that the health of the economy depends upon a healthy population.

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