The great project: how Covid changed science for ever

The emergence of a novel coronavirus prompted a wave of global collaboration that has led to vaccines, treatments and the promise of new discoveries

For scientists, 5 January was a turning point in the fight against the coronavirus. That day, a team led by Prof Yong-Zhen Zhang at Fudan University in Shanghai sequenced the genetic code of the virus behind Wuhan’s month-long pneumonia outbreak. The process took about 40 hours. Having analysed the code, Zhang reported back to the Ministry of Health. The pathogen was a novel coronavirus similar to Sars, the deadly virus that sparked an epidemic in 2003. People should take precautions, he warned.

The Chinese government had imposed an embargo on information about the outbreak and Zhang and his co-workers were under pressure not to publish the code. The blackout couldn’t hold. On 8 January, news broke about the nature of the pathogen and was confirmed a day later by Chinese authorities. To sit on the code now seemed ridiculous.

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Coronavirus: key moments – timeline

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19 – here are the points where momentum shifted

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19, it has been an extraordinary year. Here’s how the momentum shifted

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Has a year of living with Covid-19 rewired our brains?

The pandemic is expected to precipitate a mental health crisis, but perhaps also a chance to approach life with new clarity

When the bubonic plague spread through England in the 17th century, Sir Isaac Newton fled Cambridge where he was studying for the safety of his family home in Lincolnshire. The Newtons did not live in a cramped apartment; they enjoyed a large garden with many fruit trees. In these uncertain times, out of step with ordinary life, his mind roamed free of routines and social distractions. And it was in this context that a single apple falling from a tree struck him as more intriguing than any of the apples he had previously seen fall. Gravity was a gift of the plague. So, how is this pandemic going for you?

In different ways, this is likely a question we are all asking ourselves. Whether you have experienced illness, relocated, lost a loved one or a job, got a kitten or got divorced, eaten more or exercised more, spent longer showering each morning or reached every day for the same clothes, it is an inescapable truth that the pandemic alters us all. But how? And when will we have answers to these questions – because surely there will be a time when we can scan our personal balance sheets and see in the credit column something more than grey hairs, a thicker waist and a kitten? (Actually, the kitten is pretty rewarding.) What might be the psychological impact of living through a pandemic? Will it change us for ever?

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UK ‘reneges on vow to reunite child refugees with families’

Home Office accused of making ‘no arrangements’ for transfers of unaccompanied minors after EU rules expire at end of year

Unaccompanied children in France are being told by the French authorities that they should give up hope of being reunited with family in the UK after the Home Office failed to offer the help it had promised.

With the deadline to enter the UK legally and safely under the EU’s family reunification rules due to expire at the end of the year, the Home Office is accused of reneging on its vow to help unaccompanied children reunite with family in the UK.

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Origin story: what do we know now about where coronavirus came from?

When Chinese scientists alerted colleagues to a new virus last December, suspicion fell on a Wuhan market. What have health officials learned since then?

Maria van Kerkhove was staying with her sister in the US for the Christmas holidays, but checking her emails. As always. Every day there are signals of potential trouble, said the World Health Organization virologist who was to become a household name and face within weeks.

“There’s always something that happens at Christmas time. There’s always some alert, or a signal of a suspected case. The last several years it’s been Mers [Middle East respiratory syndrome] – a suspect case travelling to Malaysia or Indonesia or Korea or somewhere in Asia from the Middle East. So there’s always some kind of signal. There’s always something that happens,” she said.

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‘Our school had children who couldn’t afford event days’

The Child Poverty Action Group helped a Dundee primary make life better for deprived families

  • Please donate to our appeal here

It was the “special occasions” at her children’s school that Anna (name changed) struggled with. She and her partner both work but, with four children, stumping up the cash for Halloween costumes, Christmas jumper days or pyjama days was tricky.

“Sometimes we could manage, other times we couldn’t,” she said. “I’ve kept my kids off school in the past when we couldn’t afford to send them in with whatever it was that they were meant to have.” On other occasions, such as book fairs, she would have to borrow money.

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The magnifying glass: how Covid revealed the truth about our world

The pandemic has illuminated deprivation, inequalities and political unrest, while reminding us of the power and beauty of nature and humanity

What might be the enduring symbol of the coronavirus that turned our world upside down in 2020? Might it be those Thursday evenings of spring and summer when, at the stroke of 8pm, Britons overcame the national traits of embarrassment and reserve and ventured out on to the doorstep to applaud doctors, nurses and key workers, banging saucepans and nodding to neighbours in a synchronised “clap for carers”? Or might it be the first sign that trouble was coming this way, that footage of Italians singing to each other from their balconies in a ritual that seemed as exotic, distant and unlikely then as the very notion of a “lockdown”, back before that dramatically punitive word lost its sting?

A chequerboard computer screen of faces as Zoom became the prime means of face-to-face contact with those who didn’t live under one roof? The smaller, quieter sight of families visiting grandparents but getting no further than the garden path, toddlers waving through the glass at elderly relatives?

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‘Now it’s the girls’ dream’: Mara Gómez on becoming Argentina’s first trans footballer

Gómez made her professional debut this month, and wants to break barriers in a place where football and identity are entwined

To get a call up to your club’s first team is every Argentinian boy’s dream. Or so the traditional tango goes.

“Now it’s the girls’ dream … too,” Mara Gómez, who became the first trans footballer to play in a top-flight Argentinian league earlier this week, tells the Guardian. Gómez signed a contract with Villa San Carlos in the recently professionalized women’s Primera División, after years of journeying through the amateur leagues.

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UK Covid self-isolation period set to be reduced to 10 days

Chief medical officers of all four UK nations expected to formally announce change later on Friday

Governments across the UK are to announce a reduction in the coronavirus self-isolation period, from 14 to 10 days, it is understood.

It is expected the chief medical officers of all four UK nations will formally announce the change later on Friday.

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Death of father at hands of mob casts a dark light on rise in Malawi rape cases

Police have warned against increased vigilantism after spate of sexual abuse cases

A father who was reportedly beaten by a mob after he allegedly killed the man who attacked his daughter has died in hospital, in a case that has drawn attention to Malawi’s rise in reported rape cases.

The death of the 47-year-old man in Malawi’s capital Lilongwe was reported on Thursday. He had allegedly been beaten and left for dead by a vigilante mob, said to be relatives and friends of the man he had killed.

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Dogs and owners may share resemblance in diabetes risk

Research shows people who have a dog with type 2 diabetes are 38% more at risk of having disease themselves

It’s said that dogs resemble their owners, but the similarities may also extend to their risk of diabetes, research suggests. The same cannot be said of cat owners and their companions, however.

Previous studies had hinted that overweight owners tend to have porkier pets, possibly because of shared health behaviours such as overeating or not taking regular exercise. To investigate whether this extended to a shared risk of type 2 diabetes, Beatrice Kennedy, of Uppsala University in Sweden, and colleagues turned to insurance data from Sweden’s largest pet insurance company, using owners’ 10-digit national identification numbers to pull their anonymised health records.

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FDA advisory panel recommends approval of Pfizer Covid vaccine for emergency use

Recommendation signals formal FDA approval for Pfizer/BioNTech vaccine in the US could be imminent

An advisory panel to the US Food and Drug Administration has recommended the emergency approval of a Covid-19 vaccine developed by Pfizer and BioNTech.

The recommendation is expected to signal that the first approval of a Covid-19 vaccine for use in the US is imminent. That would mark a major milestone in a pandemic that has killed more than 285,000 Americans and 1.5 million people globally.

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Welsh secondaries and colleges to shut on Monday to stem Covid spread

Learning will move online, in contrast to England’s plans for mass testing of students

Secondary schools and colleges in Wales will close to almost all students next week and lessons will move online in an effort to stem the growing spread of coronavirus, the Welsh government has announced.

The Welsh education minister, Kirsty Williams, said the public health situation in Wales was deteriorating and she had been advised by the chief medical officer that learning should be moved online for secondary school pupils as soon as possible.

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Pornhub to ban unverified uploads after child abuse content claims

Site – visited 100m times a day – to make changes following allegations it was hosting abusive and non-consensual material

Pornhub, one of the largest adult content sites in the world, has announced it will be banning unverified video uploads after allegations that it has been hosting child abuse videos.

An investigation by the New York Times last week claimed Pornhub was hosting non-consensual and child abuse content on its website. Activists have long called for changes to Pornhub’s business model, claiming it was not carrying out sufficient checks to ensure videos were consensual.

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Rich countries leaving rest of the world behind on Covid vaccines, warns Gates Foundation

Deals struck by wealthy nations to secure treatments could leave the world’s poorest people unvaccinated without urgent action

It could be too late for any kind of fair distribution of coronavirus vaccines because of the deals already made by rich countries, according to Mark Suzman, chief executive of the Bill & Melinda Gates Foundation.

Despite the unprecedented pace of scientific progress on the development of vaccines, he said it remains “really, really complicated” to ensure they are produced and distributed fairly.

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Covid has ‘cut life expectancy in England and Wales by a year’

Exclusive: Life expectancy has regressed to 2010 levels, say scientists, with poor hardest hit

The Covid-19 pandemic has cut life expectancy in England and Wales by roughly a year, scientists have estimated, reversing gains made since 2010.

A study, conducted by Oxford researchers, found that life expectancy at birth (LEB) had fallen by 0.9 and 1.2 years for females and males relative to 2019 levels respectively.

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A Nobel prize for feeding the world can’t erase the shame of Yemen’s starving children | David Beasley

I feel pride, but can’t shake my sense of failure that the World Food Programme’s media moment comes as hunger rages

I have done the usual things you do before an awards ceremony. After extensive high-level consultation, I think I now have the right suit and tie. Carefully folded in my pocket is a long list of people to praise, many far more deserving of praise than I. I am ready.

Growing up in a small South Carolina town, I never imagined life would bring me to this moment and allow me to be part of the wonderful, blessed enterprise I have found in WFP, the World Food Programme.

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‘Deeply boring’: Martin Kenyon puzzled by vaccine video fame

TV interview outside hospital after getting jab makes 91-year-old an internet hit

A 91-year-old man whose interview with CNN after he was vaccinated for coronavirus became an internet hit said he was bemused by the commotion he caused by talking about the jab, and described anti-vaxxers as “very silly”.

Martin Kenyon, 91, was outside Guy’s hospital in London after receiving the Pfizer Covid vaccine when he encountered the CNN correspondent Cyril Vanier. Asked how it felt to be one of the first people in the world to receive the jab, he said: “I don’t think I feel much at all, except that I hope that I’m not going to have the bloody bug now.”

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NHS told not to give Covid vaccine to those with history of allergic reactions

Two health service workers experienced symptoms after receiving Pfizer vaccine

People with a history of significant allergic reactions should not receive the Covid vaccine, the medicines regulator has said, after two NHS workers experienced symptoms on Wednesday.

Both of the NHS staff carry adrenaline autoinjectors, suggesting they have suffered reactions in the past. These kind of devices, of which the best-known brand is the EpiPen, administer a swift adrenaline boost to counter allergic reactions that occur when some people, for instance, eat nuts.

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Economic cost of Covid crisis prompts call for one-off UK wealth tax

Tax experts and economists outline ‘fairest, most efficient’ way to repair public finances and quickly raise £260bn

The government has been urged to launch a one-off wealth tax on millionaire households to raise up to £260bn in response to the coronavirus pandemic, as the crisis damages Britain’s public finances and exacerbates inequality.

The Wealth Tax Commission – a group of leading tax experts and economists brought together by the London School of Economics and Warwick University to examine the case for a levy on assets – said targeting the richest in society would be the fairest and most efficient way to raise taxes in response to the pandemic.

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