Families bereaved by Covid say UK plan to allow Christmas mixing is ‘sheer madness’

Support group warns that large gatherings are too risky and calls for low-key festive period

People bereaved by Covid-19 have warned that allowing families in the UK to get together over Christmas is “sheer madness” and urged the public to have a low-key festive period rather than risk the grief they have endured.

Members of the Covid-19 Bereaved Families for Justice group told the Guardian that large family gatherings were too high-risk, with one grieving husband saying anyone prepared to mix family groups should also “prepare for a funeral”.

Continue reading...

I’m a survivor! How resilience became the quality we all crave

During the pandemic it has become a buzzword for successfully steering through adversity. But what exactly is resilience - and can you cultivate more of it?

It was after her block of flats burned down that Sadi Khan thought, finally, things could not get worse. She had married at 19, and for four years her husband had subjected her to horrific violence on an almost daily basis. She had been punched and kicked, financially controlled and constantly told she was stupid; once, a friend arrived at her flat and found her lying unconscious after an attack. So the day she accidentally set fire to her flat while cooking was simultaneously the day she lost everything and the day she started again. “He’s beaten me, I’ve lost everything,” she says. “What more can go wrong?”

Her father arrived the following day, and wanted to take her home. “I think that was the turning point,” says Khan. “When my dad was in front of me, saying: ‘Come home, let me look after you.’ I thought: ‘No, I don’t need looking after. I’m still alive. I burned the flat down, I’m still alive. I’ve been beaten up, I should have been dead five times over, but I’m still alive.’”

Continue reading...

Vaccine results bring us a step closer to ending Covid, says Oxford scientist

Latest breakthrough comes as PM says he hopes most at-risk could be immunised by Easter

The world is moving a step closer to ending the coronavirus pandemic, the scientist behind Britain’s first vaccine has declared, as Boris Johnson said he hoped the majority of those most at-risk could be immunised by Easter.

Successful trial results for the Oxford University/AstraZeneca vaccine, suggesting it could protect up to 90% of people, are the third set of promising findings in as many weeks. Before this year, there had never been a vaccine for a coronavirus.

Continue reading...

Oxford AstraZeneca vaccine to be sold to developing countries at cost price

Jab that is part of global initiative to distribute doses will remain at low price ‘in perpetuity’

The coronavirus vaccine produced by Oxford University and AstraZeneca will be available on a non-profit basis “in perpetuity” to low- and middle-income countries in the developing world.

The details of arrangements to supply poorer countries came as AstraZeneca revealed the interim results of a phase 3 trial of the vaccine, which is being heralded as the first to meet the more challenging requirements of the developing world.

Continue reading...

Oxford AstraZeneca Covid vaccine has up to 90% efficacy, data reveals

Vaccine developed in UK by AstraZeneca and Oxford University ‘will save many lives’, says scientist

A coronavirus vaccine developed in the UK can prevent 70.4% of people from getting Covid-19 and up to 90% if a lower dose is used, according to data.

Oxford University and AstraZeneca have announced their jab is effective in preventing many people getting ill and it has been shown to work in different age groups, including the elderly. There are early indications it might also help stop the spread of the disease.

Continue reading...

Family who fear daughter was killed sue Leeds NHS trust after body decomposes

Exclusive: pathologist unable to rule out third-party involvement in Emily Whelan’s death because of condition of corpse

The family of a woman who they suspect was killed is suing a health trust that allegedly stored her corpse incorrectly, allowing it to decompose to the point that experts were unable to rule out third-party involvement in her death, the Guardian can reveal.

Emily Whelan, 25, was found unresponsive in her bedroom in Leeds on 7 November 2016 and was rushed by ambulance to Leeds General Infirmary (LGI). Her family was told that Emily, who had epilepsy, had experienced a seizure, but she had never had any significant issues with the condition she had managed since childhood.

Continue reading...

Majority of Australian voters in favour of pill testing, election data shows

Long-running study finds 63% of voters support drug minimisation strategy shunned by governments

Nearly two-thirds of the Australian public are in favour of pill testing at music festivals, new national data shows.

The findings, drawn from the Australian National University’s long-running election study, show strong public support for a drug harm minimisation strategy that has largely been shunned by governments across the country despite high-profile cases of deaths at music festivals.

Continue reading...

MPs from seven parties urge government not to cut overseas aid

Letter to PM says move would send a terrible signal as UK prepares to host G7 and COP26

MPs from seven parties have urged the government not to cut the overseas aid budget, saying it had made the difference between life and death for countless people.

The intervention by MPs, including the Tory “father of the house”, Peter Bottomley, comes after it emerged that the Treasury was considering cutting more than £4bn from the aid budget and breaching a commitment to spend 0.7% of GDP on overseas assistance each year.

Continue reading...

Is this the beginning of an mRNA vaccine revolution? | Adam Finn

No one knew whether mRNA technology would work against this virus – but it does. It’s an extraordinary moment for science

The past few months have brought a number of scientific terms to public attention. We’ve had to digest R (a virus’s reproduction number) and PCR (the polymerase chain reaction method of testing). And now there’s mRNA. This last one has featured heavily in recent news reports because of the spectacular results of two new mRNA vaccines against coronavirus. It stands for “messenger ribonucleic acid”, a label familiar enough if you studied biology at O-level or GCSE, but otherwise hardly a household name. Even in the field of vaccine research, if you had said as recently as 10 years ago that you could protect people from infections by injecting them with mRNA, you would have provoked some puzzled looks.

Essentially, mRNA is a molecule used by living cells to turn the gene sequences in DNA into the proteins that are the building blocks of all their fundamental structures. A segment of DNA gets copied (“transcribed”) into a piece of mRNA, which in turn gets “read” by the cell’s tools for synthesising proteins. In the case of an mRNA vaccine, the virus’s mRNA is injected into the muscle, and our own cells then read it and synthesise the viral protein. The immune system reacts to these proteins – which can’t by themselves cause disease – just as if they’d been carried in on the whole virus. This generates a protective response that, we hope, lasts for some time. It’s so beautifully simple it almost seems like science fiction. But last week we learned that it was true.

Continue reading...

Why the race to find Covid-19 vaccines is far from over

Despite the promising news from Pfizer and Moderna, other efforts – which may be even more effective – continue around the world

While everyone celebrated this month’s news that not one but two experimental vaccines against Covid-19 have proved at least 90% effective at preventing disease in late-stage clinical trials, research into understanding how the Sars-CoV-2 virus, which causes Covid-19, interacts with the human immune system never paused.

There are plenty of questions still to answer about the Pfizer/BioNTech and Moderna vaccines: how well will they protect the elderly, for example, and how long for? Which aspects of the immune response that they elicit are protective and which aren’t? Can even better results be achieved, with vaccines that target different parts of the immune system?

Continue reading...

‘If I’m not in on Friday, I might be dead’: chilling facts about UK femicide

One woman is killed by a man every three days in the UK – a figure unchanged in a decade. A new census analyses this epidemic of male violence

In 2013, Sasha Marsden, a 16-year-old student, went to a Blackpool hotel for what she thought was an interview for a part-time cleaning job. The man she met, David Minto, 23, had lured her there on false pretences. He then sexually assaulted her and stabbed her 58 times. Sasha could only be identified by DNA taken from her toothbrush. Minto was sentenced to 35 years in prison, but for Sasha’s family, their grief has no time limit.

Gemma Aitchison, Sasha’s sister, set up YES Matters UK in response to the killing. “I wanted to know why this happened to Sasha and what I could do about it,” she explains. Part of what her organisation does is to talk to young people about consent, body image, pornography and media influence. “What I know now is that as long as women are treated as objects and not people, we will continue to be disposable.”

Continue reading...

Strewth, bloody, rooted: is there a quintessentially Australian swear word?

In this book extract, Amanda Laugesen says it’s hard to argue that Australians swear more than others, but we do our best, and we try to be inventive in the process

Linguist Geoffrey Hughes writes that “people swear by what is most potent to them”.

What is considered to be “most potent” changes across time, although taboo has often focused on the religious (hell), the sexual (fuck), and the excretory (shit). More recently racial, sexist and other discriminatory epithets have become our most taboo and controversial terms.

Continue reading...

Human rights must not be ‘trampled’ in global rush for PPE, say MPs

Calls come after Guardian finds UK sourced PPE from factories in China where North Koreans work in modern slavery

MPs and experts in the procurement of personal protective equipment have said human rights must not be “trampled” in the rush to secure PPE for frontline workers via global supply chains.

The calls come after a Guardian investigation found evidence that the British government had sourced PPE from factories in China where hundreds of North Korean women have been secretly working in conditions of modern slavery.

Continue reading...

Michael J Fox: ‘Every step now is a frigging math problem, so I take it slow’

After living with Parkinson’s for 30 years, the actor still counts himself a lucky man. He reflects on what his diagnosis has taught him about hope, acting, family and medical breakthroughs

The last time I spoke to Michael J Fox, in 2013, in his office in New York, he was 90% optimistic and 10% pragmatic. The former I expected; the latter was a shock. Ever since 1998, when Fox went public with his diagnosis of early-onset Parkinson’s disease, he has made optimism his defining public characteristic, because of, rather than despite, his illness. He called his 2002 memoir Lucky Man, and he told interviewers that Parkinson’s is a gift, “albeit one that keeps on taking”.

During our interview, surrounded by the memorabilia (guitars, Golden Globes) he has accrued over the course of his career, he talked about how it had all been for the best. Parkinson’s, he said, had made him quit drinking, which in turn had probably saved his marriage. Being diagnosed at the heartbreakingly young age of 29 had also knocked the ego out of his career ambitions, so he could do smaller things he was proud of – Stuart Little, the TV sitcom Spin City – as opposed to the big 90s comedies, such as Doc Hollywood, that were too often a waste of his talents. To be honest, I didn’t entirely buy his tidy silver linings, but who was I to cast doubt on whatever perspective Fox had developed to make a monstrously unjust situation more bearable? So the sudden dose of pragmatism astonished me. Finding a cure for Parkinson’s, he said, “is not something that I view will happen in my lifetime”. Previously, he had talked about finding “a cure within a decade”. No more. “That’s just the way it goes,” he said quietly. It was like a dark cloud had partly obscured the sun.

Continue reading...

Covid vaccine technology pioneer: ‘I never doubted it would work’

Katalin Karikó’s mRNA research helped pave way for Pfizer/BioNTech and Moderna’s successful work

The Hungarian-born biochemist who helped pioneer the research behind the mRNA technology used in the two Covid-19 vaccines showing positive results believes it was always a no-brainer.

“I never doubted it would work,” Katalin Karikó told the Guardian. “I had seen the data from animal studies, and I was expecting it. I always wished that I would live long enough to see something that I’ve worked on be approved.”

Continue reading...

Respect and value girls – they can transform Africa’s security and prosperity | Graça Machel

Investment in girls brings socioeconomic benefits, but too many countries lack the political will to bring about equality of opportunity

By 2050, Africa will be home to around half a billion girls and young women. If respected and treated as equals, they have the potential to transform the continent’s security and prosperity. This matters because every penny invested in girls’ education, healthcare and social protection benefits society many times over, while failure to invest in girls results in monumental socioeconomic losses.

Child marriage alone has resulted in human capital and revenue losses equivalent to three times the entire flow of international aid into the continent. As a mother and grandmother, it weighs heavily on me to see millions of girls robbed of their futures and the potential of our continent diminished.

Continue reading...

The cost of Christmas: Boris Johnson faces dilemma on Covid rules

PM must decide whether to listen to Tory MPs or his scientific advisers on relaxing restrictions

When Boris Johnson ordered the phased reopening of England’s shops and schools in July after a gruelling three-month lockdown, he gave the public permission to hope for a “more significant return to normality” in time for Christmas.

Four months on, and as so often in this crisis, the prime minister’s optimism appears at best premature.

Continue reading...

‘What he was doing was in plain sight’: more ex-models accuse Gérald Marie of sexual assault

Exclusive: Another seven women come forward with allegations about the former Elite boss

Seven more women have come forward to accuse the former model agency boss Gérald Marie of sexual misconduct, adding to mounting allegations that have drawn parallels with the disgraced Hollywood mogul Harvey Weinstein.

Last month a Guardian investigation revealed that nine women had made sexual misconduct allegations against Marie, who for three decades was one of the most powerful men in the fashion industry.

Continue reading...

Half of child psychiatrists surveyed say patients have environment anxiety

Research finds young people in England feel growing distress about the future of the planet

More than half of child and adolescent psychiatrists in England are seeing patients distressed about the state of the environment, a survey has revealed.

The findings showed that the climate crisis is taking a toll on the mental health of young people. The levels of eco-anxiety observed were notably higher among the young than the general population, according to the Royal College of Psychiatrists, which has just launched its first resources to help children and their parents cope with fears about environmental breakdown.

Continue reading...

Pandemic could lead to profound shift in parenting roles, say experts

Men are spending more time with their children and businesses are seeing economic benefits of flexible working

The year 2020 has been transformative for how society sees fatherhood, and could produce the most profound shift in caring responsibilities since the second world war, according to researchers, business leaders and campaigners.

Research has shown that while women bore the brunt of extra childcare during the initial coronavirus lockdown and are being disproportionately impacted by the economic fallout, there has been also a huge surge in the number of hours men are spending with their children.

Continue reading...