Operation Moonshot: Covid mass-testing trial begins in Liverpool

Asymptomatic people encouraged to get tested as scheme launches amid some confusion

The UK’s first mass-testing trial is under way in Liverpool as part of the government’s Operation Moonshot drive to test up to 10 million people a day.

Six new testing centres opened their doors to Liverpudlians at noon on Friday as the city’s health chief urged the city’s 500,000-strong population to volunteer for a coronavirus test over the next fortnight.

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How should you deal with stress in 2020? First, ditch the meditation

I thought I didn’t have a lot on, but working up disaster scenarios in my head – from the US election to the pandemic – is the closest I have come to a full-time job

The first Wednesday in November is national stress awareness day. This year, that was the day after the US elections – a sick joke that the organisers probably didn’t appreciate, being too busy taking a bath and exercising. It fell in the middle of a week dedicated internationally to stress awareness, which ends today, so you should feel free to go back to the way you were before: highly stressed, but oblivious to it. If you want to remain aware, the best way to measure cortisol, the primary stress hormone, is by analysing your earwax, according to a study from University College London’s Institute of Cognitive Neuroscience. Alternatively, you could count the unbelievably stupid things you have done over the week.

Stress is usually considered an internal state – something amiss in your mind that the outside world can perceive only by a slight squeak to your voice. (You might also get a stress headache, but only in an advert.) Really, though, it is where the internal meets the external that the problems start. Distraction, absent-mindedness: none of this would matter if you hadn’t also put your phone in the fridge and your wallet in the bin and set loose a cascade of errors to which catastrophic lateness for everything is the background music.

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Child labour doesn’t have to be exploitation – it gave me life skills | Elizabeth Sibale

Growing up in Africa taught me to be self-reliant and resilient. Putting children to work must be seen in local context

Aged eight, Tayambile would walk with her mother every day to fetch water. On her 2km return journey in 30C heat, she would carry 20 litres in an aluminium bucket on her head.

She would then help to pound maize in a mortar and prepare food for the family – typically fresh fish caught by her father on the lake.

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Covid immune response faster and stronger post-infection, scientists say

Strongest evidence yet found of sustained defence in people who recover from coronavirus

Scientists have found the strongest evidence yet that people who recover from Covid may mount a much faster and more effective defence against the infection if they encounter the virus again.

Researchers at Rockefeller University in New York found that the immune system not only remembered the virus but improved the quality of protective antibodies after an infection had passed, equipping the body to unleash a swift and potent attack if the virus invaded a second time.

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Future market for Covid vaccines ‘could be worth more than $10bn a year’

Analysts estimate revenue generated, assuming an annual jab at an average price of $20

The future market for Covid-19 vaccines could be worth more than $10bn (£7.6bn) in annual revenues for pharmaceutical companies, according to industry experts, even though some drugmakers have pledged to provide their vaccines on a not-for-profit basis during this pandemic.

The calculations by analysts at Morgan Stanley and Credit Suisse assume people will need to be vaccinated every year, similar to the traditional flu jab, with an average price of $20 for a Covid-19 vaccine dose. Prices range from $3 a dose to $37.

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Activists hail bill to make violence against LGBT people a hate crime in Italy

Bill now needs approval from upper house before becoming law

Activists in Italy have hailed a vote in the lower house of parliament to pass a bill that would make violence against LGBT people and disabled people, as well as misogyny, a hate crime.

The bill, which passed successfully despite months of protests from far-right and Catholic groups, now needs approval from the upper house, where it is backed by the ruling coalition parties, before becoming law.

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Rocky Horror’s Richard O’Brien: ‘I should be dead. I’ve had an excessive lifestyle’

The creator of the cult show is not going quietly into his 70s. He talks about coming out as trans, going ‘loopy’ on crack – and speaking in tongues after suffering a stroke

Richard O’Brien is 78, but his toothpick body and lightbulb head have always lent him a certain agelessness. A few months ago, however, the rakish Rocky Horror Show creator, Crystal Maze presenter and transgender parent-of-three received a stark reminder of his advancing years.

He was pottering around at home in New Zealand when he suddenly found himself lying on the floor. “I didn’t register that something was desperately wrong,” he says, speaking from the house he shares with his third wife, Sabrina, 10 miles outside of Katikati. “I just thought: ‘I wonder why I can’t get up.’” Struggling to his feet, he attempted to make a drink, only to discover he couldn’t put the top back on the milk. “I was in a dream-like state. Finally, I gave up with the milk, went to go back to the bedroom, slid down the wall and started speaking in tongues. That’s when Sabrina called the ambulance.”

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‘Don’t stop the music’: songs bring hope to a Nigerian psychiatric unit

There is a huge mental health treatment gap across Africa, but in one Nigerian hospital, music therapy is having a positive impact

The music comes on – a soft blend of guitar, saxophone, piano – and people sit still at first, then heads start to sway to the sound. Some hum along; mostly they sing, or laugh and dance. At the end, when quiet returns, their mood is assessed – as it was when the session started.

Once or twice a month, Bola Otegbayo brings a team of singers and instrumentalists into this psychiatric unit at University College hospital (UCH) in Ibadan, Nigeria. Otegbayo realised a few years ago that some of her patients were lonely even though their loved ones visited and caregivers provided succour. So she began to share music. Now she is a musicologist alongside her main job as a renal technologist.

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Scientists hail earwax test for checking stress hormone levels

Researchers say cortisol sampling technique could transform diagnostics for people with depression


A test that uses earwax to measure levels of the stress hormone cortisol could “transform diagnostics and care for millions of people with depression or stress-related conditions”, scientists have said.

The researchers believe the test, which can be done at home without clinical supervision, may also have the potential to measure glucose or Covid-19 antibodies that accumulate in earwax.

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Heard lost public sympathy for standing up against Depp assaults, says QC

Abused women expected to be ‘meek and subservient’ to receive public sympathy, says QC

Amber Heard’s stand against Johnny Depp’s assaults should not have deprived her of public sympathy for suffering the ordeal of domestic violence, a leading human rights lawyer has said.

Heard was subjected to death threats and misogynistic attacks on social media during the libel trial that left her feeling “down and beleaguered”, according to Helena Kennedy QC, who met Heard while the case was before the high court.

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UK can expect at least three Covid waves with lockdowns, Mordaunt says

Tory MP defends strategy as rebels warn they will not vote to extend latest restrictions

The UK should be braced for at least a third wave of the coronavirus pandemic and further lockdowns, a minister has said as Tory sceptics warned they would not vote to extend England’s four-week shutdown.

Penny Mordaunt, the paymaster general, told MPs on Tuesday that there could yet be a rolling series of lockdowns – but argued this was not evidence that the measure was ineffective.

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The women who risk their lives to deliver Pakistan’s polio vaccines

As activists target female vaccinators, Pakistan remains one of only two countries worldwide not to have eradicated polio

Nasreen Bibi never saw the face of her killer. The 44-year-old had just finished work for the day, vaccinating children against polio in Chaman, Pakistan. As she and her co-worker, Rashida Bibi (no relation), stood waiting for a rickshaw home, a motorcycle skidded up in front of them carrying two masked men.

The men did not utter a word, but through the churned up dust that filled the air, Rashida remembers seeing the raised pistol, hearing the shots and feeling the pain as the bullets hit her hands, her thighs, her back and her stomach. Rashida fell to the ground and felt Nasreen crumple beside her, blood pouring from a dark hole in her forehead.

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Lone child migrants cannot be put in adult hotels, high court rules

More under-18s seeking asylum likely to be affected by ruling against Hillingdon council

The high court has ruled that unaccompanied child migrants cannot be placed in adult hotel accommodation after three young asylum seekers won the right to be placed in the care of social services in the first case of its kind.

The three, who cannot be identified, say they are 17 years old. They arrived in the UK in July and August 2020.

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T-cell Covid immunity ‘present in adults six months after first infection’

Study suggests white blood cell levels higher in people who had symptoms

Cellular (T-cell) immunity against the virus that causes Covid-19 is likely to be present within most adults six months after primary infection, with levels considerably higher in patients with symptoms, a study suggests.

The data offers another piece of the puzzle that could be key to understanding whether previous Sars-CoV-2 infections – the virus behind Covid-19 – can prevent reinfection, and if so, for how long.

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Sean Connery had dementia, his wife reveals

Micheline Roquebrune says the late James Bond actor’s dementia ‘took its toll on him’

Sean Connery had dementia in his final months, his wife, Micheline Roquebrune, has revealed.

Speaking to the Mail on Sunday, Roquebrune said: “He had dementia and it took its toll on him. He got his final wish to slip away without any fuss.”

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Add vitamin D to bread and milk to help fight Covid, urge scientists

Widespread deficiency shows that current government guidance on supplements is failing

Scientists are calling for ministers to add vitamin D to common foods such as bread and milk to help the fight against Covid-19.

Up to half the UK population has a vitamin D deficiency, and government guidance that people should take supplements is not working, according to a group convened by Dr Gareth Davies, a medical physics researcher.

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‘It’s possible’: the race to approve a Covid vaccine by Christmas

At least three companies close to revealing results of phase three trials, but to be approved for use safety has to be ensured

The race for a Covid vaccine is reaching a crucial stage, with the glimmer of a possibility that one of the leading contenders will be approved by Christmas.

In an interview with the Guardian, Kate Bingham, who heads the UK’s vaccine taskforce, said the UK was in “a very good place”.

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New Zealand votes to legalise euthanasia in referendum

Results must be enacted by the new Labour government by November 2021, but second referendum on legalising cannabis fails to find support

New Zealanders have voted to legalise euthanasia for those with a terminal illness, in a victory for campaigners who say people suffering extreme pain should be given a choice over how and when to bring their life to a close.

The decision on whether to legalise euthanasia appeared as a referendum question on the 17 October general election ballot paper, alongside a second referendum question on whether to legalise cannabis – which did not succeed, according to preliminary results.

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Cate Blanchett: ‘Covid-19 has ravaged the whole idea of small government’

In this extract from her essay collection Upturn, the actor considers the disruptions of the pandemic and the renewed fervour for social and economic justice

The other day I had to go into town for a dental appointment. I put on all sorts of lovely clothes as if I were going out to dinner and an opening night. The prospect of being out and about was both exhilarating and daunting. I so desperately wanted to be among people and in the city, but I’d also completely forgotten what an event was. The dentist did not seem surprised by my sartorial over-commitment – but then, I was not the first patient he had seen since lockdown.

As a person working in the arts sector, the lockdown was strangely familiar on one level – a lot of actors get stuck in a kind of limbo waiting for someone else to give them permission to do what they are good at. It was as if we were all waiting by the phone for our agent to call. It was also strangely unfamiliar because the community that holds us together, the audiences, as well as the changing of the shows and the new releases, were all put on hold too. The flow between us all was severely affected, and I was both heartened and horrified when it began to surface online. Heartened because the urge to express ourselves and the desire to communicate seems undaunted by anything. Horrified because the worst place to rehearse and perform is alone in the mirror, and sometimes the phone is just a mirror.

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Nottinghamshire to ban some alcohol sales after 9pm under tier 3 Covid rules

Off-licence sales prohibition is first in the UK as beauty salons will also have to close in toughest rules yet

Nottinghamshire will be placed under tier 3 coronavirus measures from Friday, it was confirmed on Wednesday night, with a series of extra rules including the UK’s first virus-related ban on off-licence alcohol sales after 9pm.

West Yorkshire is set to follow suit within days – meaning more than 11 million people in England will soon be under the toughest level of restrictions.

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