The vaccine miracle: how scientists waged the battle against Covid-19

We trace the extraordinary research effort, from the discovery of the virus’s structure to the start of inoculations this week

In the early afternoon of 3 January this year, a small metal box was delivered to the Shanghai Public Health Clinical Centre addressed to virus expert Prof Zhang Yongzhen. Inside, packed in dry ice, were swabs from a patient who was suffering from a novel, occasionally fatal respiratory illness that was sweeping the city of Wuhan. Exactly what was causing terrifying rises in case numbers, medical authorities wanted to know? And how was the disease being spread?

Related: ‘I worked so hard in the lab. I cried when the news came’

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Different age groups may get different Covid vaccines, experts say

Oxford/AstraZeneca planning new trial of lower-dose jab to see how well it works in older people

Concerns around the efficacy of the Oxford University/AstraZeneca coronavirus jab in older people could lead to different age groups being given different vaccines, experts have said.

The partners announced last week that the vaccine had a 70% efficacy overall. For most trial participants – given two full doses, spaced a month apart – the efficacy was 62%, but for 3,000 participants mistakenly given half a dose for their first jab, the efficacy was 90%. No participants, regardless of dosing, developed severe Covid or were hospitalised with the disease.

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Vaccine results bring us a step closer to ending Covid, says Oxford scientist

Latest breakthrough comes as PM says he hopes most at-risk could be immunised by Easter

The world is moving a step closer to ending the coronavirus pandemic, the scientist behind Britain’s first vaccine has declared, as Boris Johnson said he hoped the majority of those most at-risk could be immunised by Easter.

Successful trial results for the Oxford University/AstraZeneca vaccine, suggesting it could protect up to 90% of people, are the third set of promising findings in as many weeks. Before this year, there had never been a vaccine for a coronavirus.

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Oxford AstraZeneca vaccine to be sold to developing countries at cost price

Jab that is part of global initiative to distribute doses will remain at low price ‘in perpetuity’

The coronavirus vaccine produced by Oxford University and AstraZeneca will be available on a non-profit basis “in perpetuity” to low- and middle-income countries in the developing world.

The details of arrangements to supply poorer countries came as AstraZeneca revealed the interim results of a phase 3 trial of the vaccine, which is being heralded as the first to meet the more challenging requirements of the developing world.

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The Covid vaccine results are great news, but it’s not all over yet

Oxford/AstraZeneca findings have certain advantages over those from other versions

Within weeks, the prospects of an end to the pandemic have changed utterly, with three vaccines against Covid-19 reporting good results in final clinical trials and at least one likely to be used before Christmas. But there are still huge challenges ahead.

The results from the Oxford University/AstraZeneca vaccine, which is absolutely central to the UK’s vaccination strategy, may at first glance look not as good as those of Pfizer/BioNTech and Moderna – the two mRNA vaccines that have both reported 95% efficacy.

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Moderna vaccine’s effectiveness bodes well for Oxford/AstraZeneca jab

Phase 3 success rate of 95% for US firm’s treatment is promising for UK vaccine trial

Hopes are rising for the Covid jab being developed by Oxford University, after Moderna became the second company to reveal impressive results from its vaccine trials.

Interim results from phase 3 clinical trials of the Covid vaccine from US company Moderna has revealed it to be almost 95% effective at preventing the disease. The news followed an announcement last week from Germany-based Pfizer and BioNTech that their vaccine was more than 90% effective.

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Video gaming can benefit mental health, find Oxford academics

Research based on playing time data showed gamers reported greater wellbeing

Playing video games can be good for your mental health, a study from Oxford University has suggested, following a breakthrough collaboration in which academics at the university worked with actual gameplay data for the first time.

The study, which focused on players of Nintendo’s springtime craze Animal Crossing, as well as EA’s shooter Plants vs. Zombies: Battle for Neighborville, found that people who played more games tended to report greater “wellbeing”, casting further doubt on reports that video gaming can harm mental health.

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Are we near to having a vaccine for Covid-19?

Even a once bullish PM is now not so optimistic but there are promising signs of a vaccine on the horizon

In March, Boris Johnson said we would turn the tide in 12 weeks and “send the coronavirus packing” and by May ministers were boasting of having a vaccine by September. Last week the prime minister sounded far less confident, telling MPs that there was still no vaccine for SARS, 18 years after it emerged. A vaccine may not be far away though.

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Regular UK lockdowns could help control Covid, says Sage expert

Strategy of repeated ‘circuit breakers’ would reduce total number of cases, according to leading scientific adviser

One of the government’s scientific advisers has said repeated “mini lockdowns” could be effective as a tool to bring Covid-19 cases under control.

The suggestion from Professor John Edmunds, a member of the government’s Scientific Advisory Group for Emergencies (Sage), comes amid growing evidence the virus’s prevalence is growing among older, more vulnerable people.

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Oxford University takes top spot in Guardian’s annual university guide

This year’s report sees Oxford moving up from third to first for the first time in a decade

Oxford University has vaulted into top place in the Guardian’s annual universities guide for the first time in a decade, thanks to new employment data showing that more Oxford students are moving into graduate-level jobs after completing their studies.

This year’s Guardian university guide sees Oxford moving up from third to first, while the University of St Andrews stays in second place and Oxford’s ancient rival Cambridge drops to third after occupying the top spot for nine years.

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Facebook and other tech giants ‘too big to fail’

Researchers call for new regulations to protect users, and society, in case of collapse

Like banks in the 2008 financial crisis, Facebook and other tech giants are “too big to fail”, according to research from Oxford University that calls for new regulations to protect users, and society, in the event of a possible collapse.

In their paper, published in the Internet Policy Review journal on Tuesday, Carl Öhmana and Nikita Aggarwal argue that the world’s biggest technology companies are unlikely to suddenly go out of business – but the world is unprepared for what would happen if they did.

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Number of UK citizens emigrating to EU has risen by 30% since Brexit vote

Exclusive: crisis has led to 500% increase in Britons taking up citizenship in an EU state

The number of British nationals emigrating to other EU countries has risen by 30% since the Brexit referendum, with half making their decision to leave in the first three months after the vote, research has found.

Analysis of data from the Organisation for Economic Co-operation and Development (OECD) and Eurostat shows that migration from Britain to EU states averaged 56,832 people a year in 2008-15, growing to 73,642 a year in 2016-18.

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Britain wins rare praise for leading race to test life-saving Covid drugs

UK’s high infection rate and centralised NHS have enabled Recovery team to help victims across the world

It has been a startling week for those following Britain’s response to the pandemic. Roundly derided for the lateness of its lockdown and its bungled testing programmes, the UK was the unexpected recipient of a sudden bout of lavish praise for its scientists’ efforts to combat the d isease.

“The Brits are on course to save the world,” wrote leading US economist Tyler Cowen in Bloomberg Opinion, while the journal Science quoted leading international scientists who have heaped praise on British researchers’ anti-Covid work.

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Gove and Johnson ‘sold as slaves’ at Oxford student charity event

After PM’s behaviour with the Bullingdon Club, evidence emerges of further antics at Union Society fundraiser

It may have only merited a few paragraphs in the student newspaper and have taken place 33 years ago, but an Oxford Union Society “slave auction” in which Boris Johnson and Michael Gove were involved is powerful proof of how politicians’ pasts can come back to haunt them.

“Union slave auction” was the headline in Cherwell, the journal for Oxford students, on 12 June 1987. The small story has escaped the notice of the two men’s biographers and their profile writers until now.

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Boris Johnson criticises Oxford decision to remove Rhodes statue

In wide-ranging interview, PM says jobs furlough not healthy and urges restraint as pubs open

Boris Johnson has expressed opposition to removing a statue of Cecil Rhodes from Oxford University, in a rare newspaper interview in which he also said the jobs furlough scheme was not “healthy” for the economy in the long term and would end soon.

Speaking to the Evening Standard, the prime minister said he did not agree with the decision of Oriel College to take down its statue of the Victorian imperialist, as he was “in favour of people understanding our past with all its imperfections”.

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Malala Yousafzai full of ‘joy and gratitude’ after graduating from Oxford

Educational campaigner tweets about completing philosophy, politics and economics degree

The Nobel prize-winning campaigner Malala Yousafzai has expressed her “joy and gratitude” after completing her degree at University of Oxford.

The 22-year-old shared two pictures of herself covered in confetti on Twitter with the caption: “Hard to express my joy and gratitude right now as I completed my Philosophy, Politics and Economics degree at Oxford.

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Toppling Edward Colston’s statue is unlikely to be enough to stop public anger

Few imperial icons, including Churchill, will escape the need to reappraise Britain’s past

The toppling of slaver Edward Colston’s statue has electrified a longer term – and already deeply polarised – debate among British historians and academics, with some celebrating a “moment of history” as others warned of dark consequences for society.

Inaction over figures such as Colston had bred anger that would be felt “all over Britain”, said Andrea Livesey, a historian specialising in the study of slavery and its legacies and who described the events in Bristol as “wholly justified”.

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Oxford students to get anti-bias training after George Floyd ‘joke’ at hustings

Candidate for ‘cake rep’ sparks anger after comparing killing of black man to flour shortages

An Oxford college has ordered staff and students to undergo training to combat racial bias after an undergraduate made a “joke” drawing a comparison between protests over the killing of George Floyd in Minneapolis and flour shortages.

The comments, described as racist and trivialising by witnesses, were made during a virtual hustings event by a candidate for the position of “cake rep” – a welfare position on the junior common room committee at Christ Church college.

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Greta Thunberg and Malala Yousafzai meet at Oxford University

Swedish climate activist visits Yousafzai’s college while in UK for Bristol youth protest

The teenage climate activist Greta Thunberg has met Malala Yousafzai at the University of Oxford where the Nobel peace prize winner is a student.

Yousafzai, 22, posted a photo on Instagram of herself and Thunberg sitting on a bench with their arms around each other on Tuesday, with the caption: “Thank you, @gretathunberg” and a heart emoji.

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Naomi Wolf accuses Angus Taylor of ‘antisemitic dogwhistle’ and false claim about Oxford University

Author says she was not at Oxford with Australia’s energy minister, and his implication she was part of an ‘elite’ attacking Christmas is an ‘antisemitic dogwhistle’

The American author Naomi Wolf has accused Australia’s embattled energy minister, Angus Taylor, of an “antisemitic dogwhistle”, and of falsely claiming they were at Oxford University together.

In his maiden speech to parliament in 2013, Taylor told a story about “political correctness” and a dispute over a Christmas tree at Oxford in 1991, when he was a Rhodes scholar at the university, mentioning that Wolf lived on the same corridor.

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