Psychologists pinpoint average age children become Santa sceptics

Research found little ones typically begin to distinguish fantasy from reality during preschool years

‘I cried for hours’: the moments people realised truth about Father Christmas

From empty glasses of sherry on the mantelpiece to sooty footprints leading to the bedroom door, evidence of Santa’s existence is clearly irrefutable. Yet most children will begin to question it at some point – and many parents anticipate this moment with dread. Now psychologists have identified the average age when Santa scepticism creeps in, and which children are at greatest risk of harbouring negative feelings when it does.

While most adults have fallen for the myth that Santa doesn’t exist, many children still believe – even if the idea of a single individual visiting the homes of billions of children in a single night is at odds with their wider reasoning skills.

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Five new species of soft-furred hedgehogs discovered in south-east Asia

There are now seven known species of soft-furred hedgehogs, which look like a cross between a mouse and a shrew

Scientists have identified five new species of soft-furred hedgehogs from south-east Asia.

Two of the species discovered are entirely new to science, while three have been elevated from subspecies level by researchers, who carried out DNA analysis as well as detailed physical observations of the mammals.

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‘Really, really weak’: experts attack claim that Indonesia site is ‘world’s oldest building’

Sensational report that Indonesia’s Gunung Padang site is 25,000 years old is dismissed by archaeologists around the world

It was one of the most sensational science stories of 2023. Researchers claimed last month that the Gunung Padang site in West Java, Indonesia, is the world’s most ancient pyramid and could be more than 25,000 years old.

Such antiquity would be unprecedented. Stonehenge and the oldest major pyramids of Egypt are only a few thousand years old, while the previous record holder, Turkey’s Göbekli Tepe stone monuments, are thought to be about 11,000 years old.

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Australian Medical Association accuses premiers of ‘actively undermining’ health officials’ response to Covid pandemic

AMA criticises political leaders for ‘painful lack of collaboration’ on vaccines and urges faster rollout of national centre for disease control

The Australian Medical Association has accused some premiers of “actively undermining” public health officials at points during the pandemic and said governments were now seeking to avoid criticism of their actions throughout the Covid period.

In a submission to the federal Covid inquiry, the health lobby group also urged the Labor government to speed up its rollout of a national centre for disease control to combat future pandemics, while lashing former political leaders for “a painful lack of collaboration” during the vaccine rollout.

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Revealed: the oldest black hole ever observed, dating to dawn of universe

Exclusive: astronomers surprised at size of 13bn-year-old object, which raises new questions about where black holes came from

Astronomers have detected the oldest black hole ever observed, dating back more than 13bn years to the dawn of the universe.

The observations, by the James Webb space telescope (JWST), reveal it to be at the heart of a galaxy 440m years after the big bang. At around a million times the mass of the sun, it is surprisingly big for a baby black hole, raising the question of how it grew so big so quickly.

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Comfort eating can impair body’s recovery from stress, study shows

Researchers find turning to fatty and other unhealthy foods for solace reduces vascular function and raises risk of heart disease

Using fatty foods to comfort eat during times of stress can impair the body’s recovery from the pressure, research suggests.

Many people turn to unhealthy foods such as chocolate or crisps when they are feeling the strain, but researchers have found that this can reduce blood flow to the brain and cause poorer vascular function – which in turn can have a negative effect on mental health and cognitive function, and increase the risk of heart disease.

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Sunak faces new questions at Covid inquiry after pranksters claim they reached his old phone number

PM likely to be asked about WhatsApp messages from pandemic that he says are irretrievable, despite reports number accessed

Fresh questions are being raised over whether Rishi Sunak has handed over all relevant material to the Covid inquiry after reports that pranksters have been able to access an old phone number he used during his time as chancellor.

The prime minister will face a day of questioning at the inquiry on Monday, where he is expected to be questioned about his claims that scientists had too much power. He will also be asked detailed questions about the “eat out to help out” scheme that many experts believe allowed the virus to spread.

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US regulators approve two gene therapies for sickle cell disease

Blood disorder that can lead to premature death affects estimated 100,000 people in the United States, most of whom are Black

The US Food and Drug Administration has approved a pair of gene therapies for sickle cell disease, including the first treatment based on the breakthrough Crispr gene-editing technology, opening up two “transformative therapy” avenues for some patients.

The FDA approved Lyfgenia from Bluebird Bio, and a separate treatment called Casgevy by partners Vertex Pharmaceuticals and Crispr Therapeutics. Both therapies are made from the patients’ own blood stem cells and were approved for people aged 12 and older.

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Plant fossils turn out to be turtles in ‘unusual misidentification’

Re-examination finds what were taken to be veins of leaves are actually bone growth patterns

Two small, oval fossils thought to be prehistoric plants are actually the remains of baby marine turtles, researchers have revealed.

The fossils, found in rocks dating to between 132 and 113 million years ago, were discovered in Colombia in the middle of the 20th century by Padre Gustavo Huerta, a priest with a penchant for fossil plants.

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HIV vaccine trial in Africa halted after disappointing initial results

African-led trial ended a year early as researchers conclude there is ‘little or no chance’ new combination vaccines cut HIV risk

The first trial in Africa of two combination vaccines to prevent HIV has been halted after researchers concluded it was not working.

The vaccines (part of the PrEPVacc study) were being tested on 1,500 people aged between 18 and 40 in Uganda, Tanzania and South Africa.

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Covid inquiry: Johnson surprised ‘eat out to help out’ not cleared by scientists

Former PM also angrily denies comments he made about letting Covid ‘rip’ meant he had been uncaring

Boris Johnson assumed that Rishi Sunak’s flagship “eat out to help out” hospitality scheme had been cleared by government scientists and was surprised to learn later it was not, the former prime minister has told the inquiry into Covid.

In evidence that could pose notable difficulties for the prime minister when he appears before the inquiry on Monday, Johnson said it would have been “normal” for advisers such as Chris Whitty and Patrick Vallance to have been briefed, and that he assumed this had been the case.

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Boris Johnson says he regrets questioning existence of long Covid and admits No 10 culture could be argumentative – UK politics live

Former prime minister also admits he should have worked more closely with devolved administrations

Hugo Keith KC is questioning Johnson.

He asks if Johnson’s approach has been to give all relevant material to the inquiry.

I understand the feelings of these victims and their families and I am deeply sorry for the pain and the loss and suffering of those victims and their families.

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Call to help UK IVF patients donate unused embryos after shortage hinders research

Scientists complain after ‘sheer waste’ of human embryos discarded despite patients’ wishes

Leading scientists are calling for a change in the law to help IVF patients donate unused embryos to biomedical research after a collapse in donations over the past 15 years.

The increasing commercialisation of IVF, overstretched NHS clinics and cumbersome paperwork are blamed for a 25-fold decrease in the number of donated embryos. Scientists described some patients going to “extraordinary lengths” to ensure their embryos could be used for research rather than discarded, with many private clinics failing to routinely offer donation as an option.

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Boris Johnson’s legacy will be shaped by Covid inquiry appearance

Discredited ex-PM faces a demolition job in one of the few policy areas to which he and his allies still cling

Even at the height of his popularity, Boris Johnson routinely avoided close questioning – to the extent of once hiding in a fridge to dodge a TV inquisitor. The former UK prime minister is likely to be dreading next week’s appearance at the Covid inquiry. And he probably should.

It is no exaggeration to say that events on Wednesday and Thursday at the inquiry’s repurposed office building in Paddington, west London, could help define the post-power image and legacy of Johnson, and very possibly not for the good.

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Astronomers spot ‘overweight’ planet that appears too big for tiny host star

Fact that planet 13 times bigger than Earth is orbiting star nine times smaller than sun shows ‘how little we know about the universe’

Astronomers have spotted an “overweight” planet that appears to be far too massive for its petite host star.

The planet, which is 13 times bigger than Earth, is orbiting a star called LHS 3154, which is nine times smaller than the sun. The planet’s heft is unremarkable in its own right, but its pairing with an ultracool dwarf star, the smallest and coldest stars in the universe, has puzzled scientists.

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Matt Hancock ‘was not told about eat out to help out scheme until day it was announced’ – as it happened

This live blog is now closed, you can read more on this story here

Hancock is now deploying the defence previewed in the Observer on Sunday. (See 9.58am.)

He says from the middle of January the DHSC was “trying to effectively raise the alarm”. He says:

We were trying to wake up Whitehall to the scale of the problem and this wasn’t a problem that couldn’t be addressed only from the health department. Non-pharmaceutical interventions cannot be put in place by a health department. A health department can’t shut schools. It should have been grasped and led from the centre of government earlier. And you’ve seen evidence that repeatedly the department and I tried to make this happen.

And we were on occasions blocked, and at other times our concerns were not taken as seriously as they should have been until the very end of February.

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Genetic data on 500,000 volunteers in UK to be released for scientific study

UK BioBank offers up biggest ever cache of whole-genome sequences for medical research

A new era of medical discoveries, treatments and cures is on the horizon, researchers say, following the announcement that an unprecedented trove of genetic information is to be made available to scientists.

Health researchers from around the world can now apply to study the whole genomes of half a million people enrolled in UK Biobank, a biomedical research project that has compiled detailed health and lifestyle records on individuals since it began 20 years ago.

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UK Biobank and the masses of medical data that became key to genetic research

The resource, which is on the move to Manchester, now ranks as the world’s most important health database

The origins of the UK Biobank can be traced back to a pilot study in a building in Stockport bordered by the Cheadle Heath police station on one side and the local recreation ground on the other. It was the early 2000s and scientists had realised the potential for genomics and big data to transform health research.

With diabetes, cancer, dementia and other ailments on the rise, scientists pushed for a database devoted to genetics, health and lifestyle to help them tease apart who was most at risk and how diseases could be prevented.

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‘A biodiversity catastrophe’: how the world could look in 2050 – unless we act now

The climate crisis, invasive species, overexploitation of resources and pollution could break down crucial ecosystems. We asked experts to lay out the risks and offer some solutions

The continued destruction of nature across the planet will result in major shocks to food supplies and safe water, the disappearance of unique species and the loss of landscapes central to human culture and leisure by the middle of this century, experts have warned.

By 2050, if humanity does not follow through on commitments to tackle the five main drivers of nature loss critical natural systems could break down just as the human population is projected to peak.

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‘They thought I had cancer’: painkiller banned in UK linked to Britons’ deaths in Spain

Patients’ group says reactions to metamizole can cause sepsis and organ failure – and British and Irish people are at higher risk

A patients group representing several British victims has launched legal action against the Spanish government over claims it failed to safeguard people against the potentially fatal side effects of one of the country’s most popular painkillers, involved in a series of serious illnesses and deaths.

The drug metamizole, commonly sold in Spain under the brand name Nolotil, is banned in several countries, including Britain, the US, India and Australia. It can cause a condition known as agranulocytosis, which reduces white blood cells, increasing the risk of potentially fatal infection.

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