Could microclots help explain the mystery of long Covid? | Resia Pretorius

My lab has found significant microclot formation in long Covid patients. Unfortunately, these are missed in routine blood tests

One of the biggest failures during the Covid-19 pandemic is our slow response in diagnosing and treating long Covid. As many as 100 million people worldwide already suffer from long Covid. That staggering number will eventually be much higher, if we take into account that diagnoses are still inadequate, and that we still do not know what the impact of Omicron and future variants will be.

Patients with long Covid complain of numerous symptoms, the main ones being recurring fatigue and brain fog, muscle weakness, being out of breath and having low oxygen levels, sleep difficulties and anxiety or depression. Some patients are so sick that they cannot work or even walk a few steps. There is possibly also an elevated risk of stroke and heart attacks. One of the biggest sources of concern is that even mild and sometimes asymptomatic initial Covid-19 infection may lead to debilitating, long-term disability.

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Covid clinics: hope and high prices on the long road to recovery

Yoga, mud baths and liver compresses… Welcome to the world of luxury wellness and long Covid. Amelia Tait reports on the extreme wealth divide in the search for a cure

Underneath the shadow of the snow-topped Austrian Alps, in front of a forest of thick green trees and behind a pure azure lake, sits a sprawling chalet that has seen everyone from Kate Moss to Michael Gove pass through its wide glass doors. The VivaMayr health resort in Altaussee, Austria, has long been the picturesque home of celebrity detoxes – strict bans on caffeine and alcohol, combined with stricter rules about the number of times you need to chew your food (40, naturally) have helped numerous celebrity clientele lose weight. The detoxing might sound harsh, but tranquillity oozes through the resort’s Instagram page, where enchanting mists tickle thick evergreen trees and women pose with mugs in sleek, pine interiors. It’s not the image that comes to mind when you think “long-Covid clinic”, but it is one. For £2,700 a week (excluding accommodation), sufferers can attend VivaMayr’s post-Covid medical programme, which promises a “better quality of life”.

There is currently no cure for long Covid – the condition in which individuals continue to suffer Covid-19 symptoms for months after first being infected – but there are plenty of treatments. There is an entire network of specialist NHS long-Covid clinics across the United Kingdom – here, patients can undergo rehabilitative programmes to help them improve their stamina, breathing and cognitive functions (for many, long Covid is characterised by fatigue, breathlessness, and concentration problems). Yet in September, the Office for National Statistics estimated that 1.1 million people in the UK currently suffer with long Covid, while between July and August, only 5,737 people were referred to specialist NHS clinics. With the Omicron variant threatening more lives, there’s a gap in the market for long-Covid care, and plenty of private practitioners are happy to fill it – for a price.

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Severe Covid infection doubles chances of dying in following year, study finds

Research suggests serious bouts of illness with coronavirus may significantly damage long-term health

Patients who survive severe Covid are more than twice as likely to die over the following year than those who remain uninfected or experience milder virus symptoms, a study says.

The research, published in Frontiers in Medicine, suggests that serious coronavirus infections may significantly damage long-term health, showing the importance of vaccination.

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Covid: 37% of people have symptoms six months after infection

A large study reveals the scale of long Covid, with symptoms affected by sex, age and severity of infection

One in three people infected with coronavirus will experience at least one symptom of long Covid, a new study suggests.

Much of the existing research into the condition – a mixture of symptoms reported by people often months after they were originally ill with Covid-19 – has been based either on self-reported symptoms or small studies.

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‘Hidden pandemic’: Peruvian children in crisis as carers die

With 93,000 children in Peru losing a parent to Covid, many face depression, anxiety and poverty

When Covid-19 began shutting down Nilda López’s vital organs, doctors decided that the best chance of saving her and her unborn baby was to put her into a coma.

Six months pregnant, López feared she would not wake up, or that if she did, her baby would not be there.

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Over 450 key workers with long Covid tell MPs of their struggles

Nurses, teachers, GPs and police officers among those to give evidence to cross-party inquiry

More than 450 key workers with long Covid have told a cross-party parliamentary inquiry of their experiences of the condition, including struggles to return to work and lack of financial support, with one in 10 having lost their job.

Nurses, teachers, GPs, police officers and midwives were among those who shared their experience of long Covid, symptoms of which include debilitating fatigue, shortness of breath, chest pains, sleeping difficulties and brain fog.

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Fears for Covid vaccine drive if second doses clash with boosters

Risk that low take-up by young will lead to crunch as older people get third shot

Health experts have warned the government that it needs to increase efforts to ensure more young adults are vaccinated against Covid-19 – as a matter of urgency.

They fear the current low take-up of jabs among 18- to 25-year-olds could lead to a pile-up of vaccine campaigns in September, when other groups are scheduled to get booster injections and also to be inoculated against influenza. In addition, they argue that vaccines also have a crucial role to play in protecting young adults against long Covid, which is now recognised as a serious problem associated with the disease.

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Long Covid has more than 200 symptoms, study finds

Calls for national screening programme as symptoms revealed range from brain fog to tinnitus

The largest ever international study of people with long Covid has identified more than 200 symptoms and prompted researchers to call for a national screening programme.

The study found the myriad symptoms of long Covid – from brain fog and hallucinations to tremors and tinnitus – spanned 10 of the body’s organ systems, and a third of the symptoms continued to affect patients for at least six months.

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Delta surge ‘could leave hundreds of thousands with long Covid’

Unvaccinated younger sufferers more at risk of debilitating long-term symptoms, study finds

The decision to lift England’s remaining Covid restrictions next Monday – even as cases of the Delta variant surge around the country – is expected to turbocharge the epidemic and push the nation into what one leading scientist called “uncharted territory” in terms of the numbers of people left suffering from long Covid.

Ministers have been told to expect at least one to two million coronavirus infections in the coming weeks. And while the mass rollout of vaccines – which started with elderly and vulnerable people – will dramatically reduce the proportion who are hospitalised and die, the wave may leave hundreds of thousands of younger people with long-term health problems, researchers have said.

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First year of pandemic claimed lives of 25 young people in England

Analysis, showing 4% of 5,830 children hospitalised in 12 months to February entered ICU wards, could inform vaccine policy

During the first year of the pandemic 25 children and teenagers died as a direct result of Covid-19 in England and about 6,000 were admitted to hospital, according to the most complete analysis of national data on the age group to date.

Children seen to be at greatest risk of severe illness and death from coronavirus were in ethnic minority groups, and those with pre-existing medical conditions or severe disabilities.

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Age, sex, vaccine dose, chronic illness – insight into risk factors for severe Covid is growing

A look at the demographics as 18.5 million people in the UK fall into the heightened risk category

About 18.5 million individuals, or 24.4% of the UK population, are at increased risk of developing severe Covid because of underlying health conditions. It is well known that older people are at high risk, but the understanding of all the risk factors is incomplete. Experts say that this knowledge needs to develop at speed to support policy and planning given that social restrictions will end in England on 19 July.

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Sufferers of chronic pain have long been told it’s all in their head. We now know that’s wrong

In the first of a series looking at chronic pain and long Covid, Linda Geddes explores the growing realisation that pain can be a disease in and of itself – and the pandemic could be making it worse

It started with headaches and neck pain, but no sooner had Tricia Kalinowski’s physiotherapist come up with a strategy to tackle these problems, then another area of her body would start to hurt: her lower back, her hip or her jaw.

“The physio was chasing the pain up and down my body,” says Kalinowski, 60, from Minneapolis, US. Eventually, she was referred to an oral surgeon, who believed the root cause of these issues was a problem with one of the joints in her jaw, so she underwent surgery to replace a thumbnail-sized disc.

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‘Health systems should be prepared’: doctors brace for tsunami of long Covid

As the debilitating post-viral condition affects millions around the world, medical experts are scrambling to nail down what causes it – and how to treat it

When his throat first started hurting, John Brown didn’t think much of it.

It was March 2020 and the 48-year-old was onboard the Voyager of the Seas, a cruise travelling through the Pacific Islands.

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‘Your body just stops’: long Covid sufferers face new ordeals as sick pay runs out

Nurses, teachers and shopworkers who have lost their health and their jobs talk about their struggle for support

Working seven days a week as a nurse and a fitness instructor, while bringing up two young daughters, Rebecca Logan led an extremely active life – until she contracted Covid-19 while working in the emergency department of a hospital in Northern Ireland.

Over a year after first falling ill, the 40-year-old is still suffering from long Covid. For Logan, that means she can only walk for five minutes before needing to rest, and there is a constant ringing in her ears. Her husband has had to pick up the slack at home, alongside his job as a school principal.

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Why are women more prone to long Covid?

While men over 50 tend to suffer the most acute symptoms of coronavirus, women who get long Covid outnumber men by as much as four to one

In June 2020, as the first reports of long Covid began to filter through the medical community, doctors attempting to grapple with this mysterious malaise began to notice an unusual trend. While acute cases of Covid-19 – particularly those hospitalised with the disease – tended to be mostly male and over 50, long Covid sufferers were, by contrast, both relatively young and overwhelmingly female.

Early reports of long Covid at a Paris hospital between May and July 2020 suggested that the average age was around 40, and women afflicted by the longer-term effects of Covid-19 outnumbered men by four to one.

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GPs stricken by long Covid ‘shocked and betrayed’ at being forced from jobs

Unions demand fair compensation for dozens of doctors now unable to work because of debilitating symptoms

Family doctors are being forced out of their jobs after developing long Covid, prompting demands for the government to compensate NHS staff with the debilitating condition who cannot work.

GPs struggling with the condition have told the Observer they felt “shocked and betrayed” when their colleagues removed them from their posts because of prolonged sick leave.

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Long Covid symptoms ease after vaccination, survey finds

Exclusive: Fifty-seven per cent of people with illness say they were better overall after jab

Covid-19 vaccines tend to alleviate the symptoms of long Covid, according to a large survey of more than 800 people that suggests mRNA vaccines, in particular, are beneficial.

Though Covid-19 was initially understood to be a largely respiratory illness from which most would recover within a few weeks, as the pandemic wore on increasing numbers of people reported experiencing symptoms for months on end. There is no consensus definition of the condition of these people who have symptoms ranging from chronic fatigue to organ damage, let alone a standardised treatment plan.

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‘It’s terrifying’: parents’ struggle to get help for children with long Covid

Lack of research into area means children are being sent away from A&E and parents told they are overanxious

On Christmas Day, Gail Jackson’s 16-year-old daughter said she was in so much pain she thought she would die. Liliana had been briefly admitted to hospital with Covid in September. Her symptoms never went away and, as time went on, new ones had emerged.

“For months she had a relentless, agonising headache, nausea, tinnitus, fatigue and insomnia, but the worst thing was the agonising nerve pain,” said Jackson. “I couldn’t even touch her without her screaming in pain.”

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Long Covid: many will need specialist therapies, says expert

Intensive care consultant says doctors are hoping to create a uniform structure for follow-up clinics

A “significant” number of people will require long-term aftercare such as the physiotherapy and speech therapy being received by Derek Draper after a year in intensive care following Covid, a leading doctor has said.

On Friday, it was revealed that Draper, the former political adviser and the husband of ITV presenter Kate Garraway, has been taken off support machines and returned home after a year in intensive care – but will receive 24-hour care at the couple’s newly adapted north London home.

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Publish figures on long Covid to show ‘untold suffering’, MPs urge

Cross-party group urge PM to give greater priority to potential harm posed by post-viral condition

The number of people suffering with long Covid should be published routinely, as happens with those infected with or hospitalised with coronavirus, MPs and peers are urging Boris Johnson.

The cross-party group of parliamentarians want the prime minister to ensure that the “untold human suffering” that the condition involves helps shape future government policy towards the pandemic.

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