A vast database from a little-known company called Surgisphere has influenced rapid policy shifts as the world seeks treatments for Covid-19. But as researchers began to examine it more closely, they became increasingly concerned
Dr Carlos Chaccour had just woken up in Barcelona when he opened his laptop to read the latest Covid-19 research.
Usually, he would start the day by meditating, but that was proving difficult in the middle of a global pandemic.
Continue reading...Questions raised over study claiming drug linked to higher rate of mortality and heart problems in Covid-19 patients
The World Health Organization will resume clinical trials of an anti-malaria drug researchers hope may treat Covid-19, after a study of the drug published in May by a major medical journal prompted them to halt trials due to safety concerns.
The paper, published in the Lancet, said hydroxychloroquine was associated with higher mortality rates and higher rates of heart problems in Covid-19 patients in hospitals around the world. The finding prompted the World Health Organization’s director general, Tedros Adhanom Ghebreyesus, to announce the hydroxychloroquine arm of its Solidarity global clinical trial would pause while the study and other findings were reviewed.
Continue reading...Studies under microscope after Guardian investigation reveals flaws with data from US company Surgisphere
Some scientific papers stop the world in its tracks. In the middle of a raging pandemic, a study in the world’s leading global health journal that seemed to prove President Trump wrong to laud the drug hydroxychloroquine for Covid-19 was always going to have a massive impact. It did. When the paper flagged a higher risk of death on the drug, trials were stopped all over the world, including one by the World Health Organization.
Now it’s in danger of unravelling.
Continue reading...Research appears to back up stories of people who believe they got coronavirus at events UK government allowed to go ahead
The last major football match played in England before all sport was suspended because of the coronavirus crisis was the European Champions League showpiece between Liverpool and Atletico Madrid. It was a thrilling contest that transfixed 54,000 people under the floodlights of Anfield.
But now that match, along with many other mass events that the government allowed to go ahead as the pandemic spread in March, is coming under renewed scrutiny as evidence grows of the lethal danger to which people were exposed. They include rugby matches, horse races, musical concerts and dog shows attended, in total, by hundreds of thousands of Britons.
Continue reading...Surgisphere, whose employees appear to include a sci-fi writer and adult content model, provided database behind Lancet and New England Journal of Medicine hydroxychloroquine studies
The World Health Organization and a number of national governments have changed their Covid-19 policies and treatments on the basis of flawed data from a little-known US healthcare analytics company, also calling into question the integrity of key studies published in some of the world’s most prestigious medical journals.
A Guardian investigation can reveal the US-based company Surgisphere, whose handful of employees appear to include a science fiction writer and an adult-content model, has provided data for multiple studies on Covid-19 co-authored by its chief executive, but has so far failed to adequately explain its data or methodology.
Continue reading...Yemen aid funding falls short by US$1bn; Zoom profits double; global cases pass 6.3m. Follow the latest updates
China reported one new coronavirus case and four new asymptomatic Covid-19 cases in the mainland on 2 June, the country’s health commission said.
The National Health Commission said the one confirmed case was imported involving a traveller from overseas. Mainland China had five confirmed cases, all of which were imported, and 10 asymptomatic cases for 1 June.
China does not count asymptomatic patients, those who are infected with the coronavirus but not exhibiting symptoms, as confirmed cases.
Total number of infections to date in the mainland stands at 83,021. The death toll remained unchanged at 4,634.
Dan Collyns brings you this action-packed update from Bolivia:
“Thanos is beating us” warned a Bolivian government minister in a live televised press conference on Monday as he called for his compatriots to comply with sanitary measures and lockdown restrictions amid the coronavirus pandemic.
Mientras tanto, en bolivia pic.twitter.com/5VPR4sDoX3
Continue reading...Sweden death rate now higher than France; Pakistan records largest single day rise in new infections; global deaths pass 380,000. This blog is now closed
We’ve launched a new blog at the link below:
Related: Coronavirus live news: Germany reveals major stimulus plan as global cases grow by 100,000 a day
At least three people were reported dead as coronavirus-hit Mumbai appeared to escape the worst of Cyclone Nisarga Wednesday, the first severe storm to threaten India’s financial capital in more than 70 years, AFP reports.
The city and its surrounds are usually sheltered from cyclones - the last deadly storm to hit the city was in 1948. Authorities had evacuated at least 100,000 people, including coronavirus patients, from flood-prone areas in the states of Maharashtra and Gujarat ahead of Nisarga’s arrival.
Continue reading...Wuhan doctor who worked with whistlebower dies; Abu Dhabi closes borders; Dr Fauci says he hasn’t spoken to Trump in two weeks
In England, an official study has found that black, Asian and minority ethnic (BAME) people are up to 50% more likely to die after being infected with Covid-19.
The report, published today by Public Health England (PHE), reveals that people of Bangladeshi ethnicity had around twice the risk of death than people of white British ethnicity.
It’s Simon Murphy here covering the global live blog while my colleague, Damien Gayle, takes a break.
Continue reading...Guardian told all four CMOs discussed and refused No 10 proposal, not just Chris Whitty
All four of the UK’s chief medical officers rejected suggestions from No 10 that the coronavirus threat level could be reduced because it contradicted evidence that showed the virus was still widespread, the Guardian has been told.
A senior source in one devolved government said the chief medical officers of England, Scotland, Wales and Northern Ireland discussed and refused Boris Johnson’s proposal.
Continue reading...Complaints by officials at odds with body’s public praise of Beijing’s response to outbreak
The World Health Organization struggled to get needed information from China during critical early days of the coronavirus pandemic, according to recordings of internal meetings that contradict the organisation’s public praise of Beijing’s response to the outbreak.
The recordings, obtained by the Associated Press (AP), show officials complaining in meetings during the week of 6 January that Beijing was not sharing data needed to evaluate the risk of the virus to the rest of the world. It was not until 20 January that China confirmed coronavirus was contagious and 30 January that the WHO declared a global emergency.
Continue reading...The K value sheds light on how the transmission rate varies and can help identify clusters
When deciding how and when lockdown restrictions will be lifted across the UK, the government has said the R value, denoting how many people on average one infected person will themselves infect, is crucial. But experts say another metric is becoming increasingly important: K.
Continue reading...Exclusive: thirty hospitals looking to sign up hundreds of patients to take part in studies
Five new drugs are to be trialled in 30 hospitals across the country in the race to find a treatment for Covid-19, it has emerged.
Just days after global trials of hydroxychloroquine, the drug promoted by Donald Trump as a cure, were halted, British scientists are looking to sign up hundreds of patients for trials of medicines they hope will prevent people becoming ill enough to need intensive care or ventilators.
Continue reading...Brazil becomes fourth worst country for deaths; pressure builds on South African president over his handling of outbreak
Bosnia’s state court has ordered the release of a regional prime minister and two other men suspected of corruption in connection with the import of defective ventilators for coronavirus patients.
The court of Bosnia-Herzegovina said their detention was unnecessary, and turned down the prosecution’s requests to detain the three men for 30 days.
Senior public health officials have made a last-minute plea for ministers to scrap Monday’s easing of the coronavirus lockdown in England, warning the country is unprepared to deal with any surge in infection and that public resolve to take steps to limit transmission has been eroded.
The Association of Directors of Public Health said new rules, including allowing groups of up to six people to meet outdoors and in private gardens, were “not supported by the science” and that pictures of crowded beaches and beauty spots over the weekend showed “the public is not keeping to social distancing as it was”.
Related: Health officials make last-minute plea to stop lockdown easing in England
Continue reading...As studies confirm many infected people show no symptoms, contact tracing and face masks assume even greater importance
When Noopur Raje’s husband fell critically ill with Covid-19 in mid-March, she did not suspect that she too was infected with the virus.
Raje, an oncologist at Massachusetts General Hospital in Boston, had been caring for her sick husband for a week before driving him to an emergency centre with a persistently high fever. But after she herself had a diagnostic PCR test – which looks for traces of the Sars-CoV-2 virus DNA in saliva – she was astounded to find that the result was positive.
Continue reading...Blood samples later recovered undamaged after fears incident could have helped spread virus
Monkeys mobbed an Indian health worker and made off with blood samples from coronavirus tests, prompting fears they could have spread the virus in the local area.
After making off with the three samples this week in Meerut, near Delhi, the monkeys scampered up nearby trees and one then tried to chew its plunder.
Continue reading...France prepares to enter phase two of lockdown relaxation; South Korean officials re-implement lockdown measures in Seoul; Kenya records highest one-day case rise
France announced further easing of lockdown restrictions on Thursday, with life slowly returning to normal for much of the country, writes Kim Willsher, the Guardian’s Paris correspondent. However, certain restrictions will remain in the Paris area and the overseas territories Mayotte and Guyane for at least the next three weeks.
In a 90 minute press conference, the prime minister, Édouard Philippe, said the Covid-19 figures in the country were better than expected, but urged the French to continue respecting the rules and remain careful and vigilant.
French PM Édouard Philippe has arrived for the press conference on Phase 2 of the easing of the lockdown. (I will be trying to translate and type as he speaks, so please forgive lapses in translation and grammar!).
The governor of New York, Andrew Cuomo, has said he would sign an executive order allowing businesses to deny entry to customers who are not wearing masks, the Guardian US coronavirus blog reports.
“That store owner has a right to protect himself,” Cuomo said of the order. “That store owner has a right to protect the other patrons in that store.”
Today I am signing an Executive Order authorizing businesses to deny entry to those who do not wear masks or face-coverings. No mask - No entry.
Related: Coronavirus US live: Cuomo to sign 'no mask, no entry' order for businesses
Continue reading...Qatar Covid-19 app ‘exposed 1m people’s personal details’; WHO sounds alarm over surge of Covid-19 cases in Latin America
Tom McCarthy writes that one of the key problems facing American efforts to emerge from the Covid-19 crisis is the population’s aversion to vaccines.
Only about half of Americans say they would get a Covid-19 vaccine if available, according to a poll, as a top US government scientist tempered claims by Donald Trump that the United States would be able to invent, manufacture and administer hundreds of millions of vaccine doses by the end of the year.
Related: Just half of Americans plan on getting Covid-19 vaccine, poll shows
Further to our story at 20.29, data from Johns Hopkins University shows that the United States has recorded more than 100,000 deaths from Covid-19, moving past a grim milestone even as many states relax mitigation measures to stop the spread of the novel coronavirus.
The US has recorded more deaths from the disease than any other country in the pandemic, and almost three times as many as the second-ranking country, Britain, which has recorded more than 37,000 Covid-19 deaths.
Related: US passes 100,000 coronavirus deaths as states relax lockdown measures
Continue reading...Longest official mourning period in Spain’s democracy; unrest grows in UK PM’s party over Dominic Cummings lockdown breach; WHO says Americas are new Covid-19 epicentre. Follow the latest updates
There have now been 118,000 confirmed cases of coronavirus across the 54 nations of Africa, according to the World Health Organization’s regional office for the continent.
So far, about 48,000 people in Africa who have tested positive for the virus have recovered, while 3,500 have died, according to the latest updated from WHO African region on Wednesday morning.
Over 118,000 confirmed #COVID19 cases on the African continent - with more than 48,000 recoveries & 3,500 deaths. View country figures & more with the WHO African Region COVID-19 Dashboard: https://t.co/V0fkK8dYTg pic.twitter.com/W1hbvugno1
Hi, this is Damien Gayle taking the reins of the live blog now, bringing you the latest headlines and stories, and the best of the Guardian’s coverage, from the coronavirus pandemic around the world.
If you have any comments, tips or suggestions for coverage please drop me a line, either via email to damien.gayle@gmail.com, or via Twitter direct message to @damiengayle.
Continue reading...WHO warns of second peak as global cases pass 5.5m; Irish taoiseach Leo Varadkar denies picnic with friends was rule breach; world health leaders urge green recovery
I’m handing over to my esteemed colleague Kevin Rawlinson shortly, so I’ll leave you with a summary of today’s main global developments on the coronavirus pandemic:
A diplomatic rift has broken out between Tanzania and the US. The East African nation said it had summoned the top official at the US embassy to object to an advisory that warned of “exponential growth” of Covid-19 cases in the country.
Tanzania’s divisive leader John Magufuli has repeatedly played down the gravity of the coronavirus pandemic, appearing to model his response on the early approach taken by Donald Trump in the US.
Continue reading...Malaria drug taken by Trump could raise risk of death and heart problems, study shows
The World Health Organization has said it will temporarily drop hydroxychloroquine — the malaria drug Donald Trump said he is taking as a precaution — from its global study into experimental coronavirus treatments after safety concerns.
The WHO’s director-general Tedros Adhanom Ghebreyesus said in light of a paper published last week in the Lancet that showed people taking hydroxychloroquine were at higher risk of death and heart problems than those who were not, it would pause the hydroxychloroquine arm of its solidarity global clinical trial.
Continue reading...