US germ warfare research leads to new early Covid-19 test

Exclusive: test has potential to identify carriers before they become infectious

Scientists working for the US military have designed a new Covid-19 test that could potentially identify carriers before they become infectious and spread the disease, the Guardian has learned.

In what could be a significant breakthrough, project coordinators hope the blood-based test will be able to detect the virus’s presence as early as 24 hours after infection – before people show symptoms and several days before a carrier is considered capable of spreading it to other people. That is also around four days before current tests can detect the virus.

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Lingering and painful: the long and unclear road to coronavirus recovery

People tell of symptoms coming and going weeks after falling ill, even in mild cases

Six weeks after first feeling unwell, Jenny* is still recovering from what she believes was Covid-19.

On 17 March she, like many others, began preparing for an expected lockdown in the UK, stocking up on supermarket essentials. She was feeling a little flushed – something she put down to a reemergence of cold-like symptoms from a few weeks before.

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Germany and Spain ease lockdown as Eurozone slumps 3.8% – as it happened

This blog is now closed.

We’ve launched a brand new blog at the link below. Follow me there for the latest coronavirus news from around the world, live:

Related: Coronavirus live news: Trump claims to have evidence virus started in Wuhan lab as UK is 'past the peak'

Hello, Helen Sullivan with you now. I’ll have the blog for the next few hours, so please do get in touch on Twitter @helenrsullivan.

Here are the key developments from the last few hours:

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World’s stock markets soar on coronavirus treatment hopes

Investors shrug off US growth gloom after promising data from remdesivir drug trial

Shares have soared on the world’s stock markets after investors shrugged off a deep slump in the US economy and pinned their hopes on a possible breakthrough in treatment for Covid-19.

Despite news that the longest expansion in US history came to an abrupt end in the first three months of 2020, financial markets were buoyed by an update from the American biopharma company Gilead Sciences on its experimental drug remdesivir.

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Coronavirus live news: US drug trial shows ‘clear cut’ effect, says top medic

Schools in Turkey to stay shut until end of May; Germans urged to stay home; Vietnam says it has had no domestic transmission for two weeks

Another 31 people have died in Ireland and 376 more cases have been diagnosed, the country’s chief medical officer Dr Tony Holohan has said.

One of the deaths reported on Wednesday involved a person in the 15-24 age group, the second in this category. Dr Holohan warned the number in intensive care units was too high as the prospect of a rapid easing of movement restrictions dwindles.

That is simply too high and we need to get that down further not only because it is about protecting occupancy but the lower the figure is it is a reflection of better protection of the public and lower levels of spread of the infection.

Bolivia will extend its lockdown against the pandemic until 10 May, the government has announced, though it is planning to relax rules in less affected parts of the country from the following day.

The president Jeanine Áñez has said Bolivia will move to a “dynamic” or “less rigid” quarantine on 11 May, allowing some people to return to work.

Opening the quarantine a little or closing it completely will depend on how the pandemic is being controlled in each region. The Ministry of Health will evaluate every seven days how the pandemic evolves in each region. On that basis, decisions will be taken to relax or harden the quarantine.

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France announces ‘progressive and controlled’ lockdown exit plan

Spain also plans ‘transition to normality’ despite rise in German Covid-19 infection rate after relaxation of restrictions

France and Spain have announced detailed roadmaps for gradual, phased exits from their strict coronavirus lockdowns, with restrictions to be loosened progressively and varying from region to region.

The French prime minister, Édouard Philippe, told parliament the decision to confine the population to their homes six weeks ago had saved 62,000 lives but it was now time to start lifting the lockdown to avoid economic collapse.

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Coronavirus live news: confirmed Russian cases pass China’s total; Afghanistan records biggest one-day rise in cases

Iran reports 96 more deaths; Spain’s death toll shows slight rise; Germany calls for ‘very careful’ easing of lockdown; New Zealand says ‘worst is over’

Formula One plans to start the season in Austria on 5 July and stage between 15 and 18 grands prix this year with the opening races behind closed doors.

The announcement came immediately after the French Grand Prix was cancelled and the news the British Grand Prix will be held without spectators if it goes ahead.

Preparatory work has begun on restarting repairs to Notre Dame Cathedral in Paris.

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Halt destruction of nature or suffer even worse pandemics, say world’s top scientists

Exclusive: only one species is responsible for coronavirus – humans – say world’s leading wildlife experts

The coronavirus pandemic is likely to be followed by even more deadly and destructive disease outbreaks unless their root cause – the rampant destruction of the natural world – is rapidly halted, the world’s leading biodiversity experts have warned.

“There is a single species responsible for the Covid-19 pandemic – us,” they said. “Recent pandemics are a direct consequence of human activity, particularly our global financial and economic systems that prize economic growth at any cost. We have a small window of opportunity, in overcoming the challenges of the current crisis, to avoid sowing the seeds of future ones.”

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Germany’s Covid-19 expert: ‘For many, I’m the evil guy crippling the economy’

Germany’s leading coronavirus expert Christian Drosten on Merkel’s leadership, the UK response and the ‘prevention paradox’

Christian Drosten, who directs the Institute of Virology at the Charité Hospital in Berlin, was one of those who identified the Sars virus in 2003. As the head of the German public health institute’s reference lab on coronaviruses, he has become the government’s go-to expert on the related virus causing the current pandemic.

In an exclusive interview, Drosten admits he fears a second deadly wave of the virus. He explains why Angela Merkel has an advantage over other world leaders – and why the “prevention paradox” keeps him awake at night.

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Spain’s daily death toll drops below 300 as children allowed out for first time in weeks – as it happened

WHO clarifies ‘immunity passport’ advice; global deaths pass 200,000; Russia case tally passes 80,000; Sweden’s deputy prime-minster admits problems with strategy. This blog is now closed.

We’ve launched a new blog at the link below – head there for the latest:

Related: Coronavirus live news: Boris Johnson back in Number 10 as Trump denies he plans to fire health secretary

Here a few key developments of the past few hours at a glance:

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Africa’s Covid-19 research must be tailored to its realities – by its own scientists | Monique Wasunna

Trust is essential in the pandemic and scientists here can set the priorities that make the most sense for our people

Research to find a cure and effective treatment for Covid-19 is well under way, with hundreds of trials already announced. But very few involve African researchers, and this is a mistake.

Although Africa has yet to feel the full force of the coronavirus, preventing severe cases is a higher priority than it is elsewhere. Africa needs research that is tailored to our reality.

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‘We did it to ourselves’: scientist says intrusion into nature led to pandemic

Leading US biologist Thomas Lovejoy says to stop future outbreaks we need more respect for natural world

The vast illegal wildlife trade and humanity’s excessive intrusion into nature is to blame for the coronavirus pandemic, according to a leading US scientist who says “this is not nature’s revenge, we did it to ourselves”.

Scientists are discovering two to four new viruses are created every year as a result of human infringement on the natural world, and any one of those could turn into a pandemic, according to Thomas Lovejoy, who coined the term “biological diversity” in 1980 and is often referred to as the godfather of biodiversity.

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Coronavirus detected on particles of air pollution

Exclusive: Scientists examine whether this route enables infections at longer distances

Coronavirus has been detected on particles of air pollution by scientists investigating whether this could enable it to be carried over longer distances and increase the number of people infected.

The work is preliminary and it is not yet known if the virus remains viable on pollution particles and in sufficient quantity to cause disease.

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Why are people from BAME groups dying disproportionately of Covid-19?

Co-morbidities, demographics and societal imbalances all play a part, says UCL professor Nishi Chaturvedi

One explanation for why people from black and minority ethnic (BAME) backgrounds are dying in disproportionately high numbers is demography. The virus hit London first and hit it hardest. But even when you take these regional differences into account there is a mismatch. In particular, if you take into account that ethnic minorities are generally younger – particularly important for Covid-19 where 90% of deaths are in people over 60 – the ethnic differences become even more stark.

Related: BAME groups hit harder by Covid-19 than white people, UK study suggests

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Coronavirus live news: UN warns of ‘biblical’ famine; first case seen in Palestinian refugees in Lebanon

Trump to halt immigration for 60 days initially; 256m people could starve, says UN; cases worldwide pass 2.5 million

A Chinese citizen journalist who was missing for almost two months after posting videos from Wuhan during the coronavirus outbreak has re-appeared, claiming that he was detained by police and forcibly quarantined, Lily Kuo reports from Beijing.

Li Zehua was one of three Chinese journalists who had been reporting in Wuhan during some of the worst weeks of the epidemic. He was last seen on 26 February after posting a video in which he was chased by a white SUV and an hours-long livestream that ended when several agents entered his apartment.

我是李泽华Kcriss,这是2月26日至今关于我的一些情况。I'm Kcriss, here is something about me si... https://t.co/ETjY7QaacY via @YouTube

Related: Missing Wuhan citizen journalist reappears after two months

Airlines in Europe have applied for €12.8bn (£11.3bn) in government support since the start of the coronavirus pandemic with no binding environmental conditions attached, according to an analysis of the sector’s bailout pleas, Sandra Laville reports.

By Tuesday this week, airlines including easyJet, Scandinavian Airlines and Tui had secured loans and other financial support amounting to €3.36bn. A further €9.47bn is being sought by other airlines, data tracking by Transport & Environment, Greenpeace and Carbon Watch reveals.

Related: Coronavirus: airlines seek €12.8bn in bailouts without environmental conditions attached

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Failure to protect: who is to blame for Britain’s coronavirus crisis?

A number of prominent people are being criticised for their shortcomings over Covid-19

The UK’s Covid-19 crisis has reached the blame phase, with Boris Johnson, ministers, civil servants and scientists coming under criticism that they underestimated the threat, were slow to act and are bungling the country’s response amid a wave of deaths.

So who is in the line of fire – and why?

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Global confirmed Covid-19 cases pass 2.5m but Italy sees first significant fall in infections – as it happened

This blog is now closed.

We’ve launched a new live blog at the link below where we’ll be bringing you the latest developments in the coronavirus pandemic:

Related: Coronavirus live news: UN warns of 'biblical' famine as White House prepares immigration halt

In today’s White House press briefing Trump said the US has “tested more than any country in the world, even put together.”

This is false.

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Covid-19: is seven days in isolation enough? – podcast

How long should you remain in isolation if you have symptoms of Covid-19? It depends on who you ask. The UK government guidelines recommend seven days from the onset of symptoms, whereas the World Health Organization advises 14. To get to the bottom of this apparent disparity, Nicola Davis discusses viral shedding with Dr Charlotte Houldcroft, and asks what the evidence currently tells us about how long we stay infectious for

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Will there be a second wave of coronavirus?

As countries ease lockdowns, the worry is that populations remain highly vulnerable

With more countries planning to loosen restrictions imposed due to coronavirus but the UK prime minister, Boris Johnson, and the German chancellor, Angela Merkel, concerned about the potential for a resurgence or second wave, here is what we know from the rest of the world about the risk of Covid-19 coming back.

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Coronavirus live news: Europe fatalities pass 100,000, but death rate slows in Spain and Netherlands

Saudia Arabia religious body urges all Muslims to pray at home during Ramadan; Spanish PM seeks lockdown extension

Lockdowns across Europe have had a dramatic impact on air traffic, with 90% fewer flights taking off from the continent’s largest airports compared to a year ago

Wearing face masks, waving black flags and keeping two yards apart, thousands of Israelis demonstrated against prime minister Benjamin Netanyahu under strict coronavirus restrictions on Sunday.

Netanyahu, who denies any wrongdoing, is under criminal indictment in three corruption cases.

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