Category Archives: Medical research

Spike in Ebola cases alarms health officials in DRC

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Many cases blamed on a single individual who appears to have caught virus for second time

Health officials are investigating an alarming spike in Ebola cases in the Democratic Republic of the Congo, with many blamed on a single individual who appears to have contracted the disease for a second time this year.

Amid the struggle to bring the 16-month outbreak under control, the World Health Organization noted an almost 300% increase in cases in the last three weeks, with 17 of 27 linked to a single chain of transmission.

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Polio outbreaks in Africa caused by mutation of strain in vaccine

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New cases of highly infectious disease that should be ‘consigned to the history books’ reported in Nigeria, the DRC, CAR and Angola

New cases of polio linked to the oral vaccine have been reported in four African countries and more children are now being paralysed by vaccine-derived viruses than those infected by viruses in the wild, according to global health numbers.

The World Health Organization (WHO) and partners identified nine new cases caused by the vaccine in Nigeria, the Democratic Republic of the Congo, Central African Republic and Angola last week. Along with seven other African countries with outbreaks, cases have also been reported in Asia. In Afghanistan and Pakistan polio remains endemic, and in Pakistan officials have been accused of covering up vaccine-related cases.

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Humans put into suspended animation for first time

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Groundbreaking trial in US rapidly cools trauma victims with catastrophic injury to buy more time for surgery

Doctors have put humans into a state of suspended animation for the first time in a groundbreaking trial that aims to buy more time for surgeons to save seriously injured patients.

The process involves rapidly cooling the brain to less than 10C by replacing the patient’s blood with ice-cold saline solution. Typically the solution is pumped directly into the aorta, the main artery that carries blood away from the heart to the rest of the body.

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Rabies breakthrough offers fresh hope in battle against deadly virus

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New research raises hopes of oral vaccine for dogs, the chief source of transmission to humans

Researchers have discovered a way to stop rabies from shutting down critical responses in the immune system, a breakthrough that could pave the way for new tools to fight the deadly disease.

Rabies kills almost 60,000 people each year, mostly affecting poor and rural communities.

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Two people diagnosed with pneumonic plague in China

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Authorities working to contain outbreak of disease that is worse than bubonic plague

Two people in China have been diagnosed with plague, the latest cases of a disease more commonly associated with historical catastrophe.

Plague is caused by the bacterium Yersinia pestis and can arise in three forms – a lung infection, known as pneumonic plague; a blood infection, known as septicemic plague; and a form that affects the lymph nodes, called bubonic plague.

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Any amount of running reduces risk of early death, study finds

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Previous research suggested health benefits increased with greater volume of running

Any amount of running is good for you, according to research suggesting it is linked to a similar reduction in the risk of early death no matter how many hours you clock up a week or how fast you go.

According to the World Health Organization, about 3.2 million deaths each year are down to people not doing enough physical activity.

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Quarter of world’s pig population ‘to die of African swine fever’

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World Organisation for Animal Health warns spread of disease has inflamed worldwide crisis

About a quarter of the global pig population is expected to die as a result of the African swine fever (ASF) epidemic, according to the World Organisation for Animal Health (OIE).

Global pork prices are rising spurred by growing demand from China, where as many as 100 million pigs have died since ASF broke out there last year. In recent months, China has been granting export approval to foreign meat plants and signing deals around the world at a dizzying rate. US pork sales to China have doubled, while European pork prices have now reached a six-year high.

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Scientists ‘may have crossed ethical line’ in growing human brains

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Debate needed over research with ‘potential for something to suffer’, neuroscientists say

Neuroscientists may have crossed an “ethical rubicon” by growing lumps of human brain in the lab, and in some cases transplanting the tissue into animals, researchers warn.

The creation of mini-brains or brain “organoids” has become one of the hottest fields in modern neuroscience. The blobs of tissue are made from stem cells and, while they are only the size of a pea, some have developed spontaneous brain waves, similar to those seen in premature babies.

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Our ‘inner salamander’ could help treat arthritis, study finds

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Research links human ability to regrow cartilage to molecules that help amphibians sprout new limbs

Contrary to popular opinion, humans can regrow cartilage in their joints, researchers have found. Experts hope the research could lead to new treatments for a common type of arthritis.

Osteoarthritis, in which joints become painful and stiff, is the most common form of arthritis and is thought to cause pain in about 8.5 million people in the UK alone. It is caused by a breakdown in the cartilage that protects the ends of the bones, as well as the growth of new bone around the joint as the body tries to repair the damage.

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Paralysed man walks using mind-controlled exoskeleton

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French patient’s breakthrough could lead to brain-controlled wheelchairs, say experts

A French man paralysed in a nightclub accident has walked again thanks to a brain-controlled exoskeleton, providing hope to tetraplegics seeking to regain movement.

The patient trained for months, harnessing his brain signals to control a computer-simulated avatar to perform basic movements before using the robot device to walk. Scientists described the trial results as a breakthrough.

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Caesarean babies have different gut bacteria, microbiome study finds

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C-section babies pick up more hospital bacteria than those born vaginally, research shows

Babies born by caesarean section have different gut bacteria to those delivered vaginally, the most comprehensive study to date on the baby microbiome has found.

The study showed that babies born vaginally pick up most of their initial dose of bacteria from their mother, while C-section babies have more bugs linked to hospital environments, including strains that demonstrate antimicrobial resistance. The findings could explain the higher prevalence of asthma, allergies and other immune conditions in babies born by caesarean.

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Soft drinks, including sugar-free, linked to increased risk of early death

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Drink more water, say experts as they argue study proves need for curbs on consumption

People who regularly consume soft drinks have a higher risk of an early death, researchers have found, with the trend seen for both sugared and artificially sweetened drinks.

While experts say the study cannot prove soft drinks are a driver of an increased risk of death, they say the work – which is the largest study of its kind – supports recent public health efforts to reduce consumption of soft drinks, such as the UK’s sugar tax.

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Sewage, Zika virus – and the team in Brazil mapping disease hotspots | Dom Phillips

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Volunteers in Salvador’s favelas are collecting data on deadly infections and inequality to help campaign for better sanitation

Wearing crisp, white T-shirts and carrying tablets, the students fan out through Marechal Rondon – a bustling favela spread over hillsides and a valley in Brazil’s north-eastern city of Salvador. As they walk, they map blocked drains and piles of rubbish on their tablets. These are the “infection points” that attract the rats and mosquitoes which, in turn, spread diseases like leptospirosis and the Zika virus, both prevalent here.

Student Alexandre Santos, 20, stops before a weigh-high tangle of wild plants overlooking a housing block. “We look at sewers, rubble, garbage. Now there is high vegetation,” Santos says, tapping in the data. “It goes straight into the data bank.”

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The science of senolytics: how a new pill could spell the end of ageing

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A simple treatment to stave off the health problems of old age could be available in five to 12 years. Here’s how it would work

The science of extending life is a subject of morbid fascination, conjuring the image of old billionaires being cryogenically frozen. But imagine if, instead of a pill you could take to live for ever, there was a pill that could push back the ageing process – a medicine that could stave off the fragility, osteoarthritis, memory loss, macular degeneration and cancers that plague old age.

It could happen, with the science of senolytics: an emerging – and highly anticipated – area of anti-ageing medicine. Many of the world’s top gerontologists have already demonstrated the possibilities in animals and are now beginning human clinical trials, with promising results. If the studies continue to be as successful as hoped, those who are currently middle-aged could become the first generation of oldies who are youthful for longer – with a little medical help.

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Scientists discover way to ‘grow’ tooth enamel

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Experts produce clusters of enamel-like calcium phosphate to crack age-old problem

Scientists say they have finally cracked the problem of repairing tooth enamel.

Though enamel is the hardest tissue in the body, it cannot self-repair. Now scientists have discovered a method by which its complex structure can be reproduced and the enamel essentially “grown” back.

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Breast cancer risk from using HRT is ‘twice what was thought’

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Study prompts medicines regulator to advise all women using HRT to remain vigilant

The risk of breast cancer from using hormone replacement therapy is double what was previously thought, according to a major piece of research, which confirms that HRT is a direct cause of the cancer.

The findings of the definitive study will cause concern among the 1 million women in the UK and millions more around the world who are using HRT. It finds that the longer women take it, the greater their risk, with the possibility that just one year is risk-free. It also finds that the risk does not go away as soon as women stop taking it, as had been previously assumed.

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Older adults can boost longevity ‘with just a little exercise’

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Norwegian review of 36,000 cases links more activity overall, light or intensive, with lower risk of death

Even a small increase in light activity, such as washing dishes, a little gentle gardening, or shuffling around the house, might help stave off an early death among older adults, researchers say.

Being sedentary, for instance, by sitting for long periods of time, has been linked to an increased risk of developing many conditions, including heart disease, as well as an early death.

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Ebola now curable after trials of drugs in DRC, say scientists

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Congo results show good survival rates for patients treated quickly with antibodies

Ebola can no longer be called an incurable disease, scientists have said, after two of four drugs being trialled in the major outbreak in the Democratic Republic of the Congo were found to have significantly reduced the death rate.

ZMapp, used during the massive Ebola epidemic in Sierra Leone, Liberia and Guinea, has been dropped along with Remdesivir after two monoclonal antibodies, which block the virus, had substantially more effect, said the World Health Organization and the US National Institute of Allergy and Infectious Diseases, which was a co-sponsor of the trial.

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Indian boy, seven, found with 526 teeth inside his mouth

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Teeth sized between 0.1mm to 3mm discovered in lower jaw of boy during surgery in Chennai

A seven-year-old boy who had suffered occasional toothache was found to have 526 teeth inside his jaw, according to surgeons in India.

The hundreds of teeth were found inside a sac that was nestled in the molar region of his lower jaw, following surgery carried out at the Saveetha dental college and hospital in Chennai.

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Alzheimer’s test predicts onset up to 20 years in advance

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US scientists say their blood test can be 94% effective in spotting those at risk of the illness

A blood test that can detect signs of Alzheimer’s as much as 20 years before the disease begins to have a debilitating effect has been developed by researchers in the US.

Scientists at the Washington University School of Medicine in St Louis in Missouri believe the test can identify changes in the brain suggestive of Alzheimer’s with 94% accuracy, while being much cheaper and simpler than a PET brain scan.

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