US coal power plants killed at least 460,000 people in past 20 years – report

Pollution caused twice as many premature deaths as previously thought, with updated understanding of dangers of PM2.5

Coal-fired power plants killed at least 460,000 Americans during the past two decades, causing twice as many premature deaths as previously thought, new research has found.

Cars, factories, fire smoke and electricity plants emit tiny toxic air pollutants known as fine particulate matter or PM2.5, which elevate the risk of an array of life-shortening medical conditions including asthma, heart disease, low birth weight and some cancers.

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Cheap over-the-counter nail drug found to work on crippling flesh-eating disease

‘Momentous’ breakthrough as trial finds treatment for nail infections to be highly effective for neglected tropical disease

A cheap and easily taken drug used to treat fungal nail infections has been found to work against a devastating flesh and bone-eating disease found across Africa, Asia and the Americas.

Researchers say the breakthrough offers hope to thousands of patients who have suffered decades of neglect and can face amputations if the disease is left untreated.

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Scientists raise hopes of cure for eczema itchiness with study of skin bacteria

Researchers say they have discovered a common type of bacteria can trigger irritation

Whether it’s a tickle of the nose, or an irritation in one’s hair, itches can be excruciating. Now scientists say they have found a common type of skin bacteria can trigger the sensation.

Crucially, as such bacteria are commonly found on the skin of patients with eczema – or atopic dermatitis – the work helps explain why such conditions can be accompanied by the urge to scratch.

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What we learned from Patrick Vallance at the Covid inquiry

Chief scientific adviser in pandemic says lockdown should have come sooner and that Johnson is not great at science

Sir Patrick Vallance, the UK government’s chief scientific adviser throughout Covid, has been giving evidence to the inquiry into the pandemic on Monday. Here is what we have learned so far.

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Patrick Vallance contradicts Rishi Sunak’s evidence to Covid inquiry

PM would almost certainly have known concerns over ‘eat out to help out’ scheme, says former chief scientific adviser

Rishi Sunak would almost certainly have known scientists were worried about his “eat out to help out” scheme during the pandemic, Sir Patrick Vallance has said, directly contradicting the prime minister’s evidence to the Covid inquiry.

In potentially damaging testimony, Vallance, the UK government’s chief scientific adviser during the pandemic, said he would be “very surprised” if Sunak had not learned about objections to his plan to help the hospitality industry.

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Simple blood tests for dementia to be trialled in NHS

£5m project launched with aim of having reliable tests within five years to provide quick diagnosis

Scientists are to begin piloting simple blood tests for dementia that could revolutionise detection of the disease and within five years lead to people being diagnosed in seconds by the NHS.

Currently, getting a formal diagnosis in the UK relies on mental ability tests, brain scans or invasive and painful lumbar punctures, where a sample of cerebrospinal fluid is drawn from the lower back.

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Tampon that tests for STIs created by British startup

Daye’s product doubles as PCR test for chlamydia, gonorrhoea and other common infections

A tampon is being repurposed to screen for sexually transmitted infections, with the at-home test aiming to encourage more women to seek treatment.

The gynaecological health startup Daye has launched an STI diagnostic tampon, which uses a polymerase chain reaction (PCR) test to check for chlamydia, gonorrhoea, trichomonas, mycoplasma and ureaplasma, with the tampon used in place of a swab or speculum.

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‘Alarming’ rates of babies with antibiotic-resistant bugs in Asia-Pacific, Australian study finds

Study urges Australia to research new drugs as it warns rate of mutated infections ‘much worse than anticipated’

“Alarming” rates of babies with infections resistant to common antibiotics in the Asia-Pacific region should prompt urgent investment into new drugs for treating childhood diseases, findings from a new study suggest.

The misuse and overuse of antibiotics is driving bugs to mutate so that common drugs are no longer effective to kill them, known as antimicrobial resistance. Dr Phoebe Williams, an infectious diseases paediatrician and antimicrobial resistance researcher with the University of Sydney, said she regularly travelled to work in hospitals in the south-east Asia and Pacific region where she found “entire wards of babies that have multi-drug resistant infections, and there is nothing left to treat them with”.

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Dementia could affect 1.7m people in England and Wales by 2040, data finds

Figure is 42% higher than previous estimates and would pose ‘enormous threat’ to healthcare systems

Dementia poses an “enormous threat” to healthcare systems and the general public in England and Wales, experts have warned, as data suggests 1.7 million people will have the condition by 2040.

It is already known to be among the most serious health and social care threats and a new analysis shows the total number affected could be 42% higher than previously estimated.

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Access to remains of Bambuti baby withdrawn by London museum

Hunterian had listed stillborn child of African descent as viewable for medical research but removed it after criticism from author

The remains of a stillborn Bambuti baby have been removed from a museum’s catalogue of items that can be viewed for medical research after criticism from a Booker prize-shortlisted author.

Novelist Nadifa Mohamed is the presenter of an upcoming Channel 4 documentary examining the history of “human zoos” in Britain, in which African and Asian people were put on display to the wider public in a practice which is now deemed to have been deeply racist.

Britain’s Human Zoos is on Channel 4 on Saturday 28 October

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Dementia risk factors pose more danger for ethnic minorities, finds study

Conditions such as diabetes and obesity are said to magnify risk of south Asian and black people developing the disease

The most common risk factors for dementia appear to have a more pronounced effect in black and Asian people, a study suggests, prompting calls for greater efforts to tackle health inequalities.

The number of adults living with dementia worldwide is on course to nearly triple to 153 million by 2050. Experts say the disease presents a major and rapidly growing threat to future health and social care systems in every community, country and continent.

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Cannabis brain effects study struggles to attract black UK users

Exclusive: Fears findings will represent only white population if too few people of colour take part

A major study into the effects of cannabis on the human brain is at risk of being partially thwarted because too few black users have agreed to take part.

White people have come forward in large numbers offering to get involved in King’s College London’s £2.5m study of how the drug may contribute to paranoia and psychosis in some users but not others. It is hoped the project will pave the way for wider medicinal use and make illegal recreational use safer.

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Eliminate malaria once and for all or it will come back stronger, UN warned

World faces ‘malaria emergency’ from resistance to insecticides, waning efficacy of drugs, funding shortfalls and climate change

African leaders have warned that the world is facing the “biggest malaria emergency” of the past two decades.

Heads of state and experts came together in a show of unity to call for urgent action on malaria at the UN general assembly on Friday, saying progress on eradicating the disease faced serious setbacks from mosquitoes’ growing resistance to insecticides, and the decreased effectiveness of antimalarial drugs and diagnostic tests.

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China fuels global surge in mpox cases as LGBTQ+ stigma hampers response

WHO says China facing ‘sustained community transmission’ of virus first detected as imported case last year

China is fuelling a global surge in mpox cases, accounting for the majority of new cases reported in September, according to the World Health Organization.

The number of weekly cases reported globally increased by 328% in the week to 10 September, data shows. Most of that rise came from China, where more than 500 new cases were reported in August. The WHO said China was experiencing “sustained community transmission” of the virus, which was first detected as an imported case in September last year.

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Ivani’s genetic disease is worsening as she ages. Her mother hopes Australia’s new biobank will help

Exclusive: National Muscle Disease Bio-databank will store blood test and skin biopsy samples from children with diseases such as muscular dystrophy

Bindu Shree remembers her daughter Ivani had “such a nice plump face as a baby”, but now she sees gravity pulling down her four-year-old’s cheeks as the muscles in her face become weaker.

When Ivani was diagnosed with a genetic muscle disease at four months, Shree’s first response was to ask the doctors, “What’s the treatment? What can we do to help her?”

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Ultra-processed food raises risk of heart attack and stroke, two studies show

Research presented to annual meeting of European Society of Cardiology prompts calls for action

Ultra-processed food significantly raises the risk of high blood pressure, heart disease, heart attacks and strokes, according to two studies that one expert says should serve as a wake-up call for governments worldwide.

Global consumption of heavily processed items such as cereals, protein bars, fizzy drinks, ready meals and fast food has soared in recent years. In the UK and US, well over half the average diet now consists of ultra-processed food (UPF). For some, especially people who are younger, poorer or from disadvantaged areas, a diet comprising as much as 80% UPF is typical.

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The best medicine: study finds laughter is good for heart health

Unique research shows cardiovascular gains recorded in patients who were shown TV comedy

The old adage that “laughter is the best medicine” may contain an element of truth when it comes to heart health.

A study has demonstrated that having a chuckle causes the tissue inside the heart to expand – and increases oxygen flow around the body.

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Salt-free diet ‘can reduce risk of heart problems by almost 20%’

Large new study using UK Biobank data shows even a small reduction in salt intake can be beneficial

Cutting out salt from meals can slash your risk of heart problems and strokes by almost a fifth, the largest study of its kind suggests.

Research has documented how adding salt to food increases the likelihood of cardiovascular disease and premature death. Now experts have established just how big a difference you could make to your heart health – simply by reducing the number of meals to which you add salt or by ditching it altogether.

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Political support for surveillance of Covid waning in Australia despite ‘waves of mutations’, scientists say

Active community testing required on an intermittent basis to see ‘the whole iceberg, not just the tip’, Prof Catherine Bennett says

Political momentum for the monitoring and surveillance of Covid-19 is “fading”, the Australian virologist who developed a world-first method for rapidly isolating and characterising variants said.

Prof Stuart Turville, with the University of New South Wales Kirby Institute, said while the impact of Covid-19 in Australia is waning, the Sars CoV-2 virus that causes disease is constantly changing and “there is still a lot we don’t know”.

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Woman ‘over the moon’ after sister donates womb in UK first

Pioneering operation could allow dozens of infertile women a year to have babies

Surgeons have performed the first womb transplant on a woman in the UK, opening up the possibility for dozens of infertile women to have babies every year. The woman’s sister was the living donor of the womb.

The 34-year-old was “incredibly happy” and “over the moon” with the success of the nine-hour operation, according to the medical team behind the pioneering procedure. She now plans to have two children using IVF.

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