EU agency examines reports of blood clots with J&J Covid vaccine

EMA says four serious cases reported, one fatal, and also expands inquiry into AstraZeneca vaccine

The EU’s drug regulator is reviewing reports of rare blood clots in four people who received Johnson & Johnson’s Covid-19 vaccine and has expanded its inquiry into AstraZeneca’s shot to include reports of a bleeding condition.

Of the four serious cases of clotting and low platelets, three occurred in the US during the rollout of J&J’s vaccine from its Janssen pharmaceuticals unit, the European Medicines Agency (EMA) said on Friday, adding that one person had died and one case was reported in a clinical trial. It was the first news of EMA’s inquiry into the J&J vaccine.

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Merkel sets out plan to take control of Germany’s Covid response

Bill would give national government power to impose restrictions in states with high infection rates

The German chancellor, Angela Merkel, plans to take control over the Covid-19 response from federal states to impose restrictions on regions with high numbers of new infections, as the head of the country’s disease control agency said Germany needed a two- to four-week lockdown to prevent hospitals from being overwhelmed.

“Germany is in the middle of a third wave, so the federal government and the states have agreed to add to the national legislation,” a spokesperson for the German chancellor told reporters on Friday.

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Coronavirus Australia live update: Scott Morrison announces 20m more Pfizer vaccine doses after problems with AstraZeneca-led rollout

Vaccine rollout faces delays as authorities scramble to secure alternatives to AstraZeneca such as Pfizer for under-50s over blood clot fears. Follow updates live

Labor MP Josh Burns has criticised the government for failing to deliver vaccines to aged care staff and residents, noting the issue is unrelated to fresh concerns about the AstraZeneca vaccine causing blood clotting in those under 50.

Burns’ comments follow reports in the Guardian this morning that the federal government is expected to miss a self-imposed target on delivering “pop-up” hubs to vaccinate critical aged care staff and has given no details on the proposal to workers, despite multiple requests for information and meetings from the nursing union.

We’ve not had any federal aged care providers in Macnamara receive their vaccinations or have any indication on what day they are going to be having them, not to mention the staff that are still vulnerable and haven’t been vaccinated.

The frustration that Australians rightly have is that the promises that have been made have not been made by the Labor Party, they’ve been made by Greg Hunt, they’ve been made by Scott Morrison, they’ve been telling Australians that they’ve got it under control, that all is well, they are going to be vaccinating Australians and they haven’t been.

Related: Australia’s aged care nurses still in the dark about promised ‘pop-up’ vaccination hubs

Women need more information about contraceptive options, experts said, after concerns over rare blood clots linked to the AstraZeneca Covid jab prompted a debate over side-effects caused by certain forms of the pill.

On Wednesday the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) said that evidence that the jab could be causing a rare blood clotting syndrome was growing stronger. As a result the UK’s Joint Committee on Vaccination and Immunisation (JCVI) recommended that healthy people under the age of 30 who were at low risk of Covid should be offered a different vaccine if possible.

Related: Contraception blood-clot risk: ‘public need better access to advice’

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Tens of thousands of Australians left in the lurch as AstraZeneca Covid vaccine advice changes

Doctors say their phones have been ‘running hot’ and some states bar anyone under 50 getting the AstraZeneca jab

States and territories have been left scrambling to respond to government advice recommending against vaccinating anyone under 50 with the AstraZeneca Covid-19 vaccine, leaving tens of thousands of people in the lurch.

On Friday, New South Wales halted its AstraZeneca rollout entirely for several hours while patient consent forms with the latest information about the rare risk of severe clotting associated with the vaccine were added. The state’s rollout for people aged 50 and over has since resumed.

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UK recognition of EU’s vaccine effort would not go amiss, says Brussels

Europe could have fully vaccinated 70% of adults before UK reaches its target, says head of EU taskforce

The UK will be reliant on the EU to complete its vaccine rollout and a little recognition of that would not go amiss, the European commissioner leading Brussels’ vaccine taskforce has said – adding that Europe could have fully vaccinated 70% of adults before the UK reaches its own target of one dose for all over-18s by the end of July.

Thierry Breton also said AstraZeneca had agreed that almost all the Covid vaccine doses made in the Netherlands over which the UK has made a claim will stay in the EU.

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Germany seeks Russia talks over possible supply of Sputnik V

Germany could act independently of EU but would require regulator’s approval of Covid vaccine

Germany’s health minister has said he wants to hold talks with Moscow about obtaining supplies of the Russian vaccine Sputnik V, in an effort to boost the country’s inoculation campaign.

Jens Spahn said Germany would have no hesitation in acting independently of the European Union, indicating his frustration over the bloc’s refusal to engage with the Russian jab’s manufacturers, but he stressed that the vaccine would only be used if it was approved by the European Medicines Agency (EMA).

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UK ministers silent on AstraZeneca vaccine shipment to Australia

Downing Street will not confirm or deny report that more than 700,000 Covid jabs were sent after EU blocked export

British ministers and officials did not deny that more than 700,000 shots of the AstraZeneca vaccine were secretly dispatched from the UK to Australia a few weeks ago as the EU blocked the drug’s export.

The Sydney Morning Herald reported that 717,000 AstraZeneca doses were dispatched in late February and March from the company’s British operations – also during a period when the EU was demanding the vaccine from the UK.

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Brazilian Covid variant: what do we know about P1?

What threat does variant that is causing devastation in Brazil pose, and how is it different?

The P1 variant is causing devastation in Brazil, where an uncontrolled Covid pandemic is raging. P1, behind the terrible scenes of hospital overload in Manaus with patients’ relatives pleading for oxygen cylinders, is now the dominant form of coronavirus in many of Brazil’s cities and partly responsible for the high death toll. Other Latin American countries have closed their borders and restricted travel to and from Brazil but P1 is now in at least 15 countries in the Americas, according to the Pan American Health Organization (PAHO).

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Sister of man who died after AstraZeneca jab urges public to have vaccine

Dr Alison Astles says her brother, Neil Astles, was ‘extraordinarily unlucky’ because risk of dying from vaccine is tiny

The sister of a man who died from a rare blood clot on the brain after receiving the AstraZeneca vaccine has urged the public to “keep saving lives” by continuing to receive the jab.

Neil Astles, a 59-year-old solicitor at Warrington council, was given his first dose on 17 March but died in hospital on Easter Sunday after suffering from 10 days of worsening headaches and loss of vision.

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Australian Covid vaccine rollout in disarray as AstraZeneca doses given blood clot warning for under-50s

Australian government yields to expert advice that Pfizer should now be the preferred coronavirus vaccine for adults under the age of 50

Australia’s vaccine rollout has suffered a major shock, with an advisory slapped on the AstraZeneca vaccine warning people under 50 it may cause extremely rare but potentially deadly blood clots.

On Thursday evening, the Australian government announced it had accepted expert advice that Pfizer should now be the preferred vaccine for under 50s, who will be warned AstraZeneca should only be taken if it is clear the benefits outweigh the risks.

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UK Covid variant now most common in US, says CDC chief – video

The B117 variant of coronavirus first detected in the UK is now the most dominant in the US, the director of the Centers for Disease Control and Prevention said on Wednesday.

During the White House coronavirus response team’s briefing, Dr Rochelle Walensky warned the rising number of coronavirus cases in dozens of US states is probably attributable to the spread of variants 

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‘Think of others’: elderly people in Zimbabwe dispel scepticism on Covid vaccine

While younger generations remain suspicious, growing numbers of senior citizens are taking up the jab

They may be old, frail, and vulnerable but they are the foot soldiers at the front of Zimbabwe’s Covid vaccination drive. Amid widespread scepticism among the younger population, it is elderly people who are coming out to lead by example.

The queues at the vaccination centres in the capital, Harare, are dominated by older people. At Wilkins Hospital, Felda Mupemhi, 85, grasps her walking stick as she trudges toward a white tent, where nurses are administering the Sinopharm vaccine.

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What do I need to know about the Oxford/AstraZeneca vaccine?

After a UK recommendation that healthy adults under 30 should have an alternative jab, here’s the latest information and advice

Concerns have been mounting over reports of rare but serious blood clots in a small number of recipients of the Oxford/AstraZeneca vaccine, leading to a UK recommendation on Wednesday that healthy adults under 30 should have an alternative jab if they can. We take a look at the latest information and guidance.

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India carries out record 4.3m daily Covid jabs as cases continue to rise

Country reports 115,000 fresh infections in 24 hours, the highest single-day total anywhere in world

India has carried out a record 4.3m daily vaccinations as its second wave of coronavirus continued its rapid spread, with 115,000 fresh infections in 24 hours – the highest single-day total anywhere in the world.

While the vaccination rate, which had been been hovering at between 2-3m a day, was a triumph it was not enough to quell the sense of despondency over the sharp increase in cases.

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Doubts over Russian Covid vaccine doses delay rollout in Slovakia

Sputnik V order that led to PM’s resignation cannot be used owing to incomplete or inaccurate information

A 200,000-dose order of Russia’s Sputnik V vaccine that triggered a political crisis in Slovakia should not be administered yet because of incomplete or inaccurate information from the manufacturer, the national medicines agency has said.

The Dennik N news site quoted the agency as saying it could not properly assess the shots, which it said were different from the vaccine whose favourable peer-reviewed late-stage trial results were published in The Lancet medical journal in February.

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Australia news live: mass Covid vaccination hub for Sydney could be operational in ‘couple of months’

Gladys Berejiklian says a NSW Covid immunisation centre will be capable of administering 30,000 doses a week; EU denies blocking further shipments of AstraZeneca earmarked for Australia. Follow the latest updates, live

Australia needs to manage the increasingly complex relationship with China, even as the government seeks areas to diversify its export markets, according to a new report out this afternoon.

The Asia Taskforce – which includes the Business Council of Australia and Asia Society Australia – calls for a target of boosting Australia’s exports to 35% of GDP by 2030 (up from 29% in 2019).

Popular support for the open economy cannot be taken for granted. Retreating to old familiar relationships in western markets, falling behind in Asia literacy and failing to build connections with new Asian business partners should not be seen as a serious default choice when consumption in Asia will likely fuel future global growth.

The Greens are once again calling for an independent rapid review into the vaccine rollout to identify any issues and restore public confidence.

Senator Rachel Siewert, Greens spokesperson for health, said in a statement:

With targets missed, persistent problems with vaccine supply, and troubles getting the available vaccines to where they’re needed, the rollout of these vital jabs hardly inspires confidence...

We shouldn’t let this devolve into a game of finger pointing and blaming shifting between the federal and state governments. This pointless squabble doesn’t inspire confidence in the rollout, and can only serve to add further delays to the process.

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Scott Morrison calls on European Union to supply outstanding AstraZeneca Covid vaccine doses

Australia has accused the EU of ‘semantics’ after European Commission said just one shipment of 250,000 AstraZeneca doses has been formally blocked, but Coalition says AZ has not been able to secure an export licence from Europe

Scott Morrison denies his government has presented the public with overly rosy assessments about the state of its Covid-19 vaccine rollout, as he steps up calls for the European Union to allow 3.1m outstanding AstraZeneca doses to be shipped to Australia.

While declaring that vaccine supply issues were a matter of “straightforward maths”, the prime minister also attempted to calm a growing diplomatic dispute between Australia and the EU, insisting he had not made any criticism of Brussels over its handling of the matter.

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Patients in Wales to be first in UK to receive Moderna Covid vaccine

Nation’s mass rollout begins on Wednesday, while Scotland will administer first doses later this week

Patients in Wales will from Wednesday become the first in the UK to receive the Moderna vaccine as part of a mass vaccination programme, with the first doses in Scotland set to come later this week.

The initial jabs would be given at the West Wales general hospital in Carmarthen, the Welsh government said.

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AstraZeneca Covid vaccine: weighing up the risks and rewards

Despite scientific advice to continue getting the jab, answers about fatal blood clots are urgently needed

Vaccines have side-effects, as do all medicines. Most often, jabs cause sore arms, a headache or a bit of nausea – none of which would be very significant when weighed against the toll of a serious virus such as Covid-19.

But sometimes the risk-benefit calculation may look less simple, as in the case of Oxford/AstraZeneca’s Covid jab and cerebral venous sinus thrombosis (CVST), the blood clots in the brain that have led to fatalities in the UK and Europe.

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Israel and Chile both led on Covid jabs, so why is one back in lockdown?

Analysis: contrasting national outcomes highlight how easily UK could blow its chances

As mass vaccination programmes take hold around the world, some countries have begun to get on top of the virus while others have continued to struggle. Two countries that have streaked ahead with immunisations are Israel and Chile, but as Israel edges back to a new normal, Chile has been plunged back into lockdown. Can the UK and other countries repeat Israel’s success and avoid the setbacks of Chile?

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