Why uncontrolled HIV may be behind the emergence of Omicron

Analysis: experts say weakened immune systems may give rise to new Covid variants – so HIV prevention could be key to stopping coronavirus

Where did Omicron come from? By all accounts it is a weird variant. Though highly mutated, it descended not from one of the other variants of concern, such as Alpha, Beta or Delta, but from coronavirus that was circulating maybe 18 months ago. So where has it been all this time? And why is it only wreaking havoc now?

Researchers are exploring a number of hunches. One is that Omicron arose in a remote region of southern Africa but failed to spread until now. Another is that it evolved in infected animals, such as rats, and then crossed back into humans. But a third explanation is gaining ground as more data come to light, that Omicron arose in a person with a weakened immune system: someone having cancer treatment perhaps, an organ transplant patient or someone with uncontrolled HIV.

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Javid advised to take ‘stringent’ Covid measures within a week, leak reveals

Exclusive: Health officials say urgent action needed to avoid mass hospitalisations and overwhelming the NHS

Britain’s top public health officials have advised ministers that “stringent national measures” need to be imposed by 18 December to avoid Covid hospitalisations surpassing last winter’s peak, according to documents leaked to the Guardian.

Sajid Javid, the health secretary, received a presentation from the UK Health and Security Agency (UKHSA) on Tuesday warning that even if the new Omicron variant leads to less serious disease than Delta, it risks overwhelming the NHS with 5,000 people admitted to hospital a day.

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Arrival of 1bn vaccine doses won’t solve Africa’s Covid crisis, experts say

Concerns over equipment shortages, bottlenecks and hesitancy on continent with 7.5% vaccine coverage

With 1bn doses of Covid vaccines expected to arrive in Africa in the coming months, concern has shifted to a global shortage of equipment required to deliver them, such as syringes, as well as insufficient planning in some countries that could create bottlenecks in the rollout.

After a troubled start to vaccination programmes on the continent, health officials are examining ways to encourage take-up as some countries have had to throw away doses.

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It’s time to embrace the darkness: how I got over my dread of winter

Last winter’s gloom almost broke me, so here’s what I’ve learned about changing my mindset and embracing the long, cold, dark months


It’s only now, when we have some distance from it, that we can reckon with last winter: five months of gloom, seclusion and burnout in which almost the entire country felt miserable. Against a background of a rising death toll, exhausted health workers and gross governmental incompetence – not to mention a cancelled Christmas – we were tasked with a third go at making the most of a bad situation.

I remember the moment it really got to me. It was New Year’s Eve. I’d just had a terrible and prolonged breakup, and a few days earlier had moved out of the London flat I had shared with my ex for five years. House-sitting, alone, was not the kind of New Year bash I’d envisioned, but at least I could take some solace in the thought that no one else was having much fun.

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Australia news live updates: Gladys Berejiklian rules out federal tilt; second woman killed in Queensland floods

Former NSW premier confirms she won’t run in federal election; second Queensland woman found dead in floodwaters. Follow all the day’s developments

By the way, we are expecting to hear from Scott Morrison pretty soon about the recently Atagi approvals for children’s vaccinations.

Berejiklian:

Well, I promised when the PM and others contacted me and urged me to give it consideration. I promised them and I did for a very short period of time and then obviously let them know that it’s not something I want to pursue and it is just a different direction.

I want my life to change.

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CDC chief says Omicron is ‘mild’ as early data comes in on US spread of variant

Agency is working on detailed analysis of what the new mutant form of the coronavirus might hold for the US

More than 40 people in the US have been found to be infected with the Omicron variant so far, and more than three-quarters of them had been vaccinated, the chief of the Centers for Disease Control and Prevention (CDC) has said. But she added nearly all of them were only mildly ill.

In an interview with the Associated Press, Dr Rochelle Walensky, director of the CDC, said the data is very limited and the agency is working on a more detailed analysis of what the new mutant form of the coronavirus might hold for the US.

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Bondi backpackers hostel Noah’s locked down due to Covid scare as NSW reports 420 cases

NSW police confirm health department requested assistance at Sydney venue

A Bondi Beach backpackers hostel in Sydney has been placed into lockdown for a second time due to fears of a Covid outbreak.

It is not yet known how many people were staying at Noah’s backpackers hostel or whether the Omicron strain of the virus was present.

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Debacle over No 10 Christmas party ‘threatens efforts to control pandemic’

Scientists say rule-breaking ‘could damage public compliance behaviours when they are more important than ever’

The debacle over the No 10 Christmas party threatens to undermine efforts to control the Covid pandemic at a time when the Omicron variant is fuelling fears of an imminent and major wave of disease, say scientists.

A so-called Cummings effect last year led to “negative and lasting consequences” on public trust following the lockdown-busting trips made by Boris Johnson’s aide, Dominic Cummings, researchers found.

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Omicron spreads to 57 countries but too early to tell if variant more infectious, WHO says

World Health Organization says new Covid variant spreading rapidly in South Africa, with cases doubling in the past week

The Omicron variant of Covid-19 has now been reported in 57 countries and continues to spread rapidly in South Africa, the World Health Organization (WHO) says.

But the latest epidemiological report from WHO says given the Delta variant remains dominant, particularly in Europe and the US, it is still too early to draw any conclusions about the global impact of Omicron.

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New Zealand to ban smoking for next generation in bid to outlaw habit by 2025

Legislation will mean people currently aged 14 and under will never be able to legally purchase tobacco

New Zealand has announced it will outlaw smoking for the next generation, so that those who are aged 14 and under today will never be legally able to buy tobacco.

New legislation means the legal smoking age will increase every year, to create a smoke-free generation of New Zealanders, associate health minister Dr Ayesha Verrall said on Thursday.

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Barnaby Joyce, Australia’s deputy PM, tests positive for Covid while visiting US

Nationals leader is experiencing mild symptoms and will remain in isolation until further advice

Australia’s deputy prime minister, Barnaby Joyce, has tested positive to Covid-19 while on a visit to the United States.

The government says Joyce – who was in London earlier this week and met with the British justice secretary, Dominic Raab, and the Australian high commissioner to the UK, George Brandis – will isolate in the US until it is safe for him to return to Australia.

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Anger as Jair Bolsonaro to allow unvaccinated visitors into Brazil

There are fears the decision will reverse the gains made by a successful vaccination campaign

The Brazilian government has been accused of seeking to turn the South American country into a haven for unvaccinated tourists after it shunned calls – including from its own health regulator – to demand proof of vaccination from visitors.

The decision – announced on Tuesday by the health minister, Marcelo Queiroga – sparked anger in a nation that has lost more than 615,000 lives to a Covid outbreak the president, Jair Bolsonaro, stands accused of catastrophically mishandling.

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Queensland declares ‘world first’ Omicron Covid genetic variation but experts say it is not a new variant

Sub-lineage described as Omicron ‘like’ was identified in an overseas arrival to the state from South Africa

Queensland has declared a “world-first” sub-lineage of Omicron but experts say it’s not a new variant or a new strain and more information is needed.

The new Omicron Covid sub-lineage, known as Omicron “like”, was identified in an overseas arrival to Queensland from South Africa.

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Australia’s fertility rate falls to record low in 2020

Registered births fell by 3.7% in 2020, with the total fertility rate at an all-time low of 1.58 babies per woman

Australia’s fertility rate continues to plummet, with registered births dropping below 300,000 for the first time in 14 years.

Figures released by the Australian Bureau of Statistics on Wednesday showed there were 294,369 registered births in 2020, a decrease of 3.7% from 2019. The previous year’s decline was 3%.

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Scientists find ‘stealth’ version of Omicron not identifiable with PCR test

Researchers fear new Covid variant could spread unnoticed because rough means of flagging up cases does not work

Scientists have identified a “stealth” version of the Omicron variant which cannot be detected with the routine tests that public health officials are using to track its spread around the world.

The stealth variant has many mutations in common with standard Omicron, but it lacks a particular genetic change that allows lab-based PCR tests to be used as a rough and ready means of flagging up probable cases.

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As many as 6 million eligible Britons may not have had a Covid jab. Who are they?

The Omicron variant has refocused attention on vaccination rates as data shows disparities in uptake across age, region and ethnicity

Hundreds of cases of the new Omicron Covid-19 variant have now been confirmed in the UK and experts have called for a renewed focus on vaccination rates.

As of 4 December, just over eight in 10 people aged 12 or older UK-wide had received two doses of a coronavirus vaccine, according to data from the UK Health Security Agency, while 89% had received a first dose. This means about 6 million eligible people may still be unvaccinated, based on ONS population figures as opposed to counts of GP records. So who are they?

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Michele Brown was vaccinated – but had a suppressed immune system. Would better health advice have saved her?

The mother-of-two carefully shielded until the government said it was safe to see friends and family. She had no idea how her existing conditions could affect her

The feeling of relief was immense as 58-year-old Michele Brown returned home from the vaccine centre. Her husband, Terry, 61, had taken time off from his job as a supervisor at a heavy machinery factory to drive her to her second Covid-19 vaccination at a Gateshead community centre. In the car, Michele told her partner of 40 years that she felt like a weight had been lifted off her shoulders. “She said: ‘At least we’ve got that done,’” Terry remembers. “‘We’ll be OK.’”

It was 28 April 2021. Michele, who had rheumatoid arthritis, an underactive thyroid and diabetes, had spent the last year and a half shielding indoors, on government advice. She was careful. She had a Covid station set up on the breakfast counter: lateral flow tests, bottles of antibacterial gel and disposable face masks. When family came to visit, a mask-wearing Michele would banish them to the furthest corner of the living room. “We couldn’t kiss her,” remembers her daughter, Kim Brown, 41, who lives in Durham. “She would say: ‘You might have the coronies! I don’t want no coronies. You’re not giving me that crap.’”

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Australia live news update: NSW teachers’ strike closes nearly 400 public schools; Victoria pandemic bill becomes law

David Littleproud says ‘conversations are happening’ about Olympics boycott; NSW teachers’ strike closes nearly 400 public schools; three new Omicron cases detected in ACT, six Covid-19 infections overall; Victoria pandemic bill becomes law; ; Victoria records 1,185 cases and seven deaths; NSW records 260 cases and two deaths – follow all the day’s news

A suspected shark attack on Victoria’s Bellarine Peninsula has left two teens in hospital and shut a beach, reports Callum Godde from AAP.

Emergency services were called to Ocean Grove, south east of Geelong, just after 7pm on Monday.

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Covid live: early signs Omicron more transmissible, UK PM says; Scottish firms urged to let staff work from home

Early indications Omicron more transmissible than Delta, says Boris Johnson; Nicola Sturgeon says staff should work from home until mid-January

All international arrivals to the UK are now required to take a pre-departure Covid-19 test to tackle the new Omicron variant.

The tightened requirements have just come into force from 4am (GMT) on Tuesday 7 December.

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Viagra could be used to treat Alzheimer’s disease, study finds

US scientists say users of sildenafil – the generic name for Viagra – are 69% less likely to develop the form of dementia than non-users

Viagra could be a useful treatment against Alzheimer’s disease, according to a US study.

Alzheimer’s disease, the most common form of age-related dementia, affects hundreds of millions of people worldwide. Despite mounting numbers of cases, however, there is currently no effective treatment.

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