Woman successfully treated for depression with electrical brain implant

‘Stunning’ neuroscientific advance gives hope to those with mental illness not helped with drugs

A woman with severe depression has been successfully treated with an experimental brain implant in a “stunning” advance that offers hope to those with intractable mental illness.

The device works by detecting patterns of brain activity linked to depression and automatically interrupting them using tiny pulses of electrical stimulation delivered deep inside the brain.

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How standup comedy helped me conquer anxiety, depression – and fear of public speaking

Finding a humorous angle to some of my darkest episodes – and sharing them with strangers – was strangely cathartic

“Have you gone mad?” asked one friend. “You’re so brave. I could never do that. Wouldn’t meditation be wiser?” said another. For someone with a long history of depression and anxiety, plus a morbid fear of public speaking, taking up standup comedy might seem like a masochistic decision. Yet to me it makes perfect sense. Excruciating fear of failure is at the heart of most people’s aversion to attempting to make a room full of strangers laugh. But controlling that fear, and not succumbing to it, is the central reason I’ve chosen to expose myself in this very public and potentially humiliating way.

I grew up in comfortable, middle-class suburban Hertfordshire in the 1970s and 80s, but my upbringing was a complex one of emotional uncertainty. Years of therapy have lent me an understanding of how I learned to cope over the years. To avoid facing difficult issues during my childhood and teenage years I buried my emotions, and that evasion only escalated in adulthood. By my early 20s, I was mentally ill-equipped to deal with life’s thornier challenges.

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Facebook aware of Instagram’s harmful effect on teenage girls, leak reveals

Social media firm reportedly kept own research secret that suggests app worsens body image issues

Facebook has kept internal research secret for two years that suggests its Instagram app makes body image issues worse for teenage girls, according to a leak from the tech firm.

Since at least 2019, staff at the company have been studying the impact of their product on its younger users’ states of mind. Their research has repeatedly found it is harmful for a large proportion, and particularly teenage girls.

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‘No sense of safety’: how the Beirut blast created a mental health crisis

A year on from the devastating explosion, people are struggling to sleep and PTSD is widespread – amid economic chaos

Rayan Khatoun has been dreading 4 August. She has been constantly on edge as the anniversary of the port explosion in Beirut approached.

The blast threw Khatoun into a wall as she came home from work and left her with a head injury, a fractured cheekbone and torn tendons. Since then, she has suffered from recurring nightmares, insomnia and anxiety attacks.

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Revealed: the secret trauma that inspired German literary giant

WG Sebald’s writing on the Holocaust was driven by the anger and distress he felt over his father’s service in Hitler’s army

His books are saturated with despair. Over and over again, his emotionally traumatised characters are caught – inescapably – in plots that doom them to a life of anguish. Often, they kill themselves.

Now, the psychological wounds and suicidal thoughts that blighted WG Sebald’s own life and secretly inspired him to begin writing fiction are to be laid bare for the first time in a forthcoming biography.

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‘I am very shy. It’s amazing I became a movie star’: Leslie Caron at 90 on love, art and addiction

The legendary actor reflects on her riches-to-rags childhood, confronting depression and alcoholism – and dancing with Gene Kelly and Fred Astaire

Leslie Caron and her companion, Jack, greet me at the front of their apartment. They make a well-matched couple – slight, chic, immaculately coiffured. Caron, the legendary dancer and actor, is 90 in two weeks’ time. Jack, her beloved shih tzu, is about nine.

Caron heads off to make the tea, with Sidney Bechet’s summery jazz playing in the background. I am left alone with Jack to explore the living room. It feels as if I am tunnelling through the history of 20th-century culture. Here is a photo of a pensive François Truffaut; below is a smirking Warren Beatty. The centrepiece on the wall is a huge watercolour of Caron’s great friend Christopher Isherwood, painted by his partner, Don Bachardy. To the left is Louis Armstrong, to the right Rudolf Nureyev, with whom she starred in 1977’s Valentino, and further along is Jean Renoir, who she says was like a father to her. And we have barely started.

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Can magic mushrooms really help you understand bitcoin?

That’s what one German billionaire says. But it’s not why the Aztecs and the hippies were such fans

Name: The shroom boom.

Age: Ancient rock art in Castilla-La Mancha in Spain suggests that Psilocybe hispanica, one of the mushrooms that contains the psychoactive compound psilocybin, was taken in religious ceremonies as long as 6,000 years ago.

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‘The ketamine blew my mind’: can psychedelics cure addiction and depression?

This week sees the opening of the first UK high-street clinic offering psychedelic-assisted therapy. Could popping psilocybin be the future of mental healthcare?

In the summer of 1981, when he was 13, Grant crashed a trail motorbike into a wall at his parents’ house in Cambridgeshire. He’d been hiding it in the shed, but “it was far too powerful for me, and on my very first time starting it in the garden, I smashed it into a wall”. His mother came outside to find the skinny teenager in a heap next to the crumpled motorbike. “I was in a lot of trouble.”

Grant hadn’t given this childhood memory much thought in the intervening years, but one hot August day in 2019, it came back to him with such clarity that, at 53, now a stocky father of two, he suddenly understood it as a clue to his dangerously unhealthy relationship with alcohol.

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Why it’s time to stop pursuing happiness

Positive thinking and visualising success can be counterproductive – happily, other strategies for fulfilment are available

Like many teenagers, I was once plagued with angst and dissatisfaction – feelings that my parents often met with bemusement rather than sympathy. They were already in their 50s, and, having grown up in postwar Britain, they struggled to understand the sources of my discontentment at the turn of the 21st century.

“The problem with your generation is that you always expect to be happy,” my mother once said. I was baffled. Surely happiness was the purpose of living, and we should strive to achieve it at every opportunity? I simply wasn’t prepared to accept my melancholy as something that was beyond my control.

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Scientists hail earwax test for checking stress hormone levels

Researchers say cortisol sampling technique could transform diagnostics for people with depression


A test that uses earwax to measure levels of the stress hormone cortisol could “transform diagnostics and care for millions of people with depression or stress-related conditions”, scientists have said.

The researchers believe the test, which can be done at home without clinical supervision, may also have the potential to measure glucose or Covid-19 antibodies that accumulate in earwax.

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Lockdown having ‘pernicious impact’ on LGBT community’s mental health

UCL and Sussex University study finds younger people confined with bigoted relatives the most depressed

The coronavirus lockdown has provoked a mental health crisis among the LGBTQ community, with younger people confined with bigoted relatives the most depressed, researchers found.

A study of LGBTQ people’s experience during the pandemic, by University College London (UCL) and Sussex University, found 69% of respondents suffered depressive symptoms, rising to about 90% of those who had experienced homophobia or transphobia.

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‘I saw so much killing’: the mental health crisis of South Sudan refugees

Therapy is helping some of the thousands forced over the border to Uganda to cope, but funding shortfalls mean resources are becoming scarcer

As darkness fell, Rebecca closed the door to her makeshift home. The day was over.

The 29-year-old, who had been uprooted from South Sudan to a north Ugandan refugee settlement, sat on the bed where her four children slept and, at around 10pm, tried to take her own life. “By then I didn’t care about anything – not myself, not even my kids. The pain was too extreme,” she says. Her children awoke and their cries brought help from neighbours.

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Depression and suicide linked to air pollution in new global study

Cutting toxic air might prevent millions of people getting depression, research suggests

People living with air pollution have higher rates of depression and suicide, a systematic review of global data has found.

Cutting air pollution around the world to the EU’s legal limit could prevent millions of people becoming depressed, the research suggests. This assumes that exposure to toxic air is causing these cases of depression. Scientists believe this is likely but is difficult to prove beyond doubt.

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‘My mother-in-law called me Walter White’: how magic mushrooms rescued me from grief

After our daughter’s death I was overwhelmed by pain and anxiety. Microdosing home-grown mushrooms helped me cope

It was spring when my wife’s waters broke, three months early. We rushed to hospital, terrified. If our daughter arrived now, she might not survive. If she did, she would probably be plagued by lifelong health problems. Jo spent the next four days in hospital, while we prayed labour wouldn’t begin. But the night after we returned home, Jo’s contractions started and we raced back to hospital. Straight away, a foetal monitor was placed on her tummy. The brisk heartbeat we had been following so closely in the previous days was gone. Our daughter had died.

The train of our life was shunted on to a parallel track. We could see the train we were meant to be on pulling away, passing the milestones – the due date, introducing the baby to our family, the first smiles. But ahead of us now lay despair, guilt, a funeral, photos of our precious girl that some family members could barely bring themselves to look at, and support groups where every story would be more heart-rending than the last. There is no right way to deal with losing a baby, but I would call my coping strategy unusual: I became obsessed with growing magic mushrooms.

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Austerity and inequality fuelling mental illness, says top UN envoy

Exclusive: Special rapporteur on health says social justice more important for mental health than therapy and medication

Austerity, inequality and job insecurity are bad for mental health and governments should counteract them if they want to face up to the rising prevalence of mental illness, the UN’s top health envoy has said.

In an exclusive interview with the Guardian to coincide with a hard-hitting report to be delivered to the UN in Geneva on Monday, Dr Dainius Pūras said measures to address inequality and discrimination would be far more effective in combatting mental illness than the emphasis over the past 30 years on medication and therapy.

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Exercise helped with my anxiety – but I became obsessed. Therapy was the answer

It wasn’t until I had a back injury that I realised how extreme my gym habit had become – and admitted that I needed help

The first time I went for a run as an adult, I was at university and had been deeply depressed for several months. I managed a minute before I had to walk, but, I told myself, a minute was a start. I went every day and, as the weeks passed, I ran further, for longer. The impact was immediate – even after that first jog I felt a rush of achievement, of hope. And it was cumulative: every run that followed made me feel stronger, physically and emotionally. Then, one day, many months later, I realised I was not depressed any more.

As the years passed, I gradually branched out from short jogs into runs of more than two hours. I went to circuit classes and step classes, interval training and personal training, core sessions and legs, bums and tums sessions. I dropped two dress sizes and developed stomach muscles.

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New drug raises hopes of reversing memory loss in old age

Toronto researchers believe the drug can also help those with depression, schizophrenia and Alzheimer’s

An experimental drug that bolsters ailing brain cells has raised hopes of a treatment for memory loss, poor decision making and other mental impairments that often strike in old age.

The drug could be taken as a daily pill by over-55s if clinical trials, which are expected to start within two years, show that the medicine is safe and effective at preventing memory lapses.

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After Spade and Bourdain, Schumer Wants to Increase Funding for Suicide Prevention

It was hard not to sit back and really examine the prevalence of suicide last week after two celebrities, Kate Spade and Anthony Bourdain, both took their own lives. Sen. Chuck Schumer must have been thinking about it as well, and along with a report on the state of suicides across the country, he wants to increase funding for suicide prevention.