Pfizer and BioNTech’s vaccine poses global logistics challenge

Europe and US create vast facilities for Covid-19 vaccine but poorer nations lack infrastructure, say experts

Two vast football-pitch-sized facilities equipped with hundreds of large freezers in Kalamazoo, Michigan, and Puurs, Belgium, will be the centres of the huge effort to ship the coronavirus vaccine, developed by US drug giant Pfizer and German biotech firm BioNTech, around the world.

Governments are scrambling to prepare for the rollout of the vaccine, which must be stored at -70C (-94F), after the announcement from the two companies that it was more than 90% effective and had no serious side-effects. The news sparked hopes of a return to normal life and a stock market rally, but now minds are turning to the practicalities of getting the vaccine quickly to populations across the world, in particular to the vulnerable people who need it most.

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Amazon charged with abusing EU competition rules

US tech firm accused by Brussels of using data it collects on retailers

Amazon has been charged by the European commission with using the sales data of independent retailers selling through its site to illegally gain an advantage in the European market place.

The US tech firm and online retailer was accused by Brussels of using the information it collects on retailers to focus its own efforts on the bestselling products with the biggest profit margins.

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UK trade department faces race to get £80bn of trade agreements ratified

Deals to ensure UK can go on trading with non-EU countries after Brexit transition must be laid before MPs by Wednesday

Liz Truss’s Department for International Trade (DIT) is scrambling to meet a Wednesday deadline for tabling £80bn of trade agreements before parliament, in time for them to come into force in January under standard procedures.

Truss’s department has signed a string of “continuity agreements” to ensure the UK can go on trading with non-EU countries on similar terms, when the Brexit transition period comes to an end on 31 December.

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Pfizer/BioNTech vaccine announcement is cause for cautious celebration

Interim trial results are encouraging as scientists welcome news

It is not yet the end of the pandemic, but the announcement by Pfizer/BioNTech that their vaccine has been 90% successful in the vital large-scale trials has got even the soberest of scientists excited.

These are interim results and the trial will continue into December to collect more data. The two companies – a tiny German biotech with the big idea and the giant pharma company Pfizer with the means to develop it – have not yet published their detailed data, so it is all on trust. And yet, nobody is suggesting the results have been over-egged. It looks as though the vaccine not only works, but works better than anyone hoped.

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‘It’s the screams of the damned!’ The eerie AI world of deepfake music

Artificial intelligence is being used to create new songs seemingly performed by Frank Sinatra and other dead stars. ‘Deepfakes’ are cute tricks – but they could change pop for ever

‘It’s Christmas time! It’s hot tub time!” sings Frank Sinatra. At least, it sounds like him. With an easy swing, cheery bonhomie, and understated brass and string flourishes, this could just about pass as some long lost Sinatra demo. Even the voice – that rich tone once described as “all legato and regrets” – is eerily familiar, even if it does lurch between keys and, at times, sounds as if it was recorded at the bottom of a swimming pool.

The song in question not a genuine track, but a convincing fake created by “research and deployment company” OpenAI, whose Jukebox project uses artificial intelligence to generate music, complete with lyrics, in a variety of genres and artist styles. Along with Sinatra, they’ve done what are known as “deepfakes” of Katy Perry, Elvis, Simon and Garfunkel, 2Pac, Céline Dion and more. Having trained the model using 1.2m songs scraped from the web, complete with the corresponding lyrics and metadata, it can output raw audio several minutes long based on whatever you feed it. Input, say, Queen or Dolly Parton or Mozart, and you’ll get an approximation out the other end.

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Covid set back attitudes to public transport by two decades, says RAC

Most Britons see their car as more important now and would not choose greener alternative

The pandemic has put back attitudes to driving versus public transport by two decades, with almost two-thirds of UK car owners now considering their vehicle essential, research has found.

A clear majority would now refuse to switch to a greener alternative even if better trains or buses were available, according to the RAC. The research for its annual Report on Motoring found reluctance to use public transport was now at its highest for 18 years.

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EU bank supports projects linked to human rights violations, NGOs claim

European Investment Bank accused of failure to properly assess impacts of supported projects in Africa and Asia

The EU-funded European Investment Bank has been using taxpayer cash to support infrastructure projects linked to alleged human rights violations, an investigation by NGOs shows.

The report – led by campaign groups Counter Balance and the CEE Bankwatch Network – has accused the EIB of a lack of transparency and a failure to properly assess the impact of its funding as it extends its role beyond Europe to former Soviet republics, Africa and Asia.

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‘It’s crazy, but I started my own bank’: the story behind Starling

Fed up with modern finance and Britain’s broken banking system, Anne Boden decided there was only one thing to do: set up a bank that ran in the way she wanted it to

The first time I met Anne Boden was last December at a glitzy awards ceremony where I knew no one, felt out of place and was skulking in the loos. In she bustled – she’s smaller than me (I’m 5ft 1in), older than me (she’s 60), a little eccentric and perhaps the friendliest person in the place. She didn’t stop talking. She ushered me out, remained by my side until the ceremony started (think Disney’s Fairy Godmother) and, along the way, mentioned that she was the founder and CEO of Starling Bank, the event’s main sponsor.

I couldn’t have been more surprised – or picture a less likely “banking mogul”. When she explained that Starling was an app-based bank, I rewarded her with the worst response possible. “You mean like Monzo?” (My daughter had signed up to Monzo, the trendy “no branches” bank, to acquire its distinctive coral-coloured card, which now gathers dust on her bookshelf.) Boden was gracious but flustered. I ascertained that Monzo had been founded by her former business partner Tom Blomfield. He was considerably younger, more hip, more Hoxton – and he’d left her, taking the other directors with him.

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Raw sewage dumped into English and Welsh beaches ‘2,900 times this year’

Exclusive: public health and environment at risk as water companies overuse emergency overflows, says pressure group

Water companies discharged raw sewage into bathing water beaches almost 3,000 times in the past year, polluting the environment and risking public health, new analysis shows.

Related: Face masks and gloves found on 30% of UK beaches in clean-up

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Victoria’s hotel quarantine program revealed to cost $195m – as it happened

Four new coronavirus cases recorded in NSW southern highlands as Victoria quarantine inquiry delivers interim report. This blog is now closed

That’s it for tonight, thanks for reading. To recap today’s developments:

The chief of the defence force, Angus Campbell, has released a statement about the inquiry into alleged war crimes by Australian special forces in Afghanistan.

Campbell said he received the Afghanistan inquiry report today, which examined the conduct of elite Australian forces in more than 55 incidents of alleged unlawful killings between 2005 and 2016.

Today I have received the Afghanistan Inquiry report from the Inspector-General of the Australian Defence Force (IGADF).

The independent inquiry was commissioned by Defence in 2016 after rumours and allegations emerged relating to possible breaches of the Law of Armed Conflict by members of the Special Operations Task Group in Afghanistan over the period 2005 to 2016.

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UK coronavirus live: Boris Johnson holds news briefing on first day of England’s new lockdown

Latest updates: PM gives televised address after Sunak extends furlough until end of March

Q: What is your response to concerns about the data presented by government? (See 4.11pm.)

Johnson says the government is happy to share the data it has.

Q: Won’t we have to live with restrictions for some time?

Stevens says the NHS is prepared for coronavirus.

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Future market for Covid vaccines ‘could be worth more than $10bn a year’

Analysts estimate revenue generated, assuming an annual jab at an average price of $20

The future market for Covid-19 vaccines could be worth more than $10bn (£7.6bn) in annual revenues for pharmaceutical companies, according to industry experts, even though some drugmakers have pledged to provide their vaccines on a not-for-profit basis during this pandemic.

The calculations by analysts at Morgan Stanley and Credit Suisse assume people will need to be vaccinated every year, similar to the traditional flu jab, with an average price of $20 for a Covid-19 vaccine dose. Prices range from $3 a dose to $37.

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Spain announces plans for flying taxi service in Barcelona

First air taxis to fly in Catalan capital and Santiago de Compostela in 2022, says Enaire

When Spain’s much-missed tourists and pilgrims finally return, they may be offered a novel way to rise above the crowds and appreciate some of the country’s most dramatic urban architecture.

Enaire, Spain’s air navigation authority, has announced plans to begin demonstrating flying taxis in Barcelona and Santiago de Compostela in 2022.

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Markets rally as investors brace for US election – business live

Rolling coverage of the latest economic and financial news

Mohit Kumar of Jefferies reckons the battle for the Senate could be worth $2tn in potential stimulus measures:

In terms of market impact, a clear result should be positive for risk sentiment, irrespective of a Biden or Trump win.

From a fiscal stimulus perspective, as we have argued before, the Senate elections are as important, if not more, than a Presidential one. A ‘Blue Wave’ with Biden as the President and Democrats having control of both the House and the Senate would see a fiscal stimulus of over $3trn.

Related: The Senate races to watch on election night

This morning’s rally in Europe follows a strong day’s trading for shares in the Asia-Pacific region.

China’s CSI 300 index gained 1.2%, and Hong Kong’s Hang Seng jumped by nearly 2%, while Australia’s S&P/ASX 200 rose 1.9% after the RBA slashed interest rates to record lows.

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‘This is revolutionary’: new online bookshop unites indies to rival Amazon

Bookshop.org, which launched in the US earlier this year, has accelerated UK plans and goes online this week in partnership with more than 130 shops

It is being described as a “revolutionary moment in the history of bookselling”: a socially conscious alternative to Amazon that allows readers to buy books online while supporting their local independent bookseller. And after a hugely successful launch in the US, it is open in the UK from today.

Bookshop was dreamed up by the writer and co-founder of Literary Hub, Andy Hunter. It allows independent bookshops to create their own virtual shopfront on the site, with the stores receiving the full profit margin – 30% of the cover price – from each sale. All customer service and shipping are handled by Bookshop and its distributor partners, with titles offered at a small discount and delivered within two to three days.

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Russia rules out cutting fossil fuel production in next few decades

Energy minister says Moscow will also focus on clean-burning hydrogen and carbon capture

Russia has no plans to rein in its production of fossil fuels in the coming decades despite the global efforts to shift towards low-carbon energy, according to its energy minister.

Alexander Novak told the Guardian that Russia did “not see that we will achieve a peak in [gas] production anytime soon” because the world’s appetite for gas would continue to grow in the decades ahead despite its growing number of climate targets.

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Transport for London secures £1.8bn government bailout

Government backs down on demands for fare increases in significant win for Sadiq Khan

Transport for London (TfL) has secured a bailout from the government worth about £1.8bn just a fortnight after Boris Johnson said Sadiq Khan had “effectively bankrupted” the tube and bus service in the capital.

In a significant win for the London mayor, the government has backed down on demands for fare increases, an extension of the congestion zone to cover the entire city and the scrapping of free fares for children and over-60s.

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Nightmare before Christmas: M&S set for big loss on Covid-hit high street

Its Ocado tie-up may bring Marks festive joy, but as restrictions and uncertainty bite, even Primark looks less than cheerful

The next two months are supposed to be the most lucrative time of the year for the high street, but a grisly update from Marks & Spencer will this week provide a grim reality check as the pandemic sets up nightmarish trading conditions for the golden quarter.

Analysts expect M&S to have made a loss of about £60m in the first six months of its financial year because of the huge sales hit suffered by its clothing arm during the three-month spring lockdown. This time last year, the UK’s biggest clothing retailer was reporting profits of £176m.

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How plot linked to Kremlin fooled UK peers into fake ‘murder’ probe

Son-in-law of Russian oligarch seeks apology from parliamentarians

It was a murder straight from the McMafia playbook, a killing that connected Moscow to London and high finance to a criminal underworld.

In its aftermath, a group of Siberian miners launched a campaign to get justice for the murdered man – Evgeny Lazarevich, a coal mine manager who had apparently fallen foul of a magnate whose profits flowed into London via Cyprus.

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Ecotricity founder to grow diamonds ‘made entirely from the sky’

UK millionaire Dale Vince says lab-grown gems will be ‘world’s first zero-impact’ diamonds

A British multi-millionaire and environmentalist has set out plans to create thousands of carats of carbon-negative, laboratory-grown diamonds every year “made entirely from the sky”.

Dale Vince, the founder of green energy supplier Ecotricity, claims to have developed the world’s only diamonds to be made from carbon, water and energy sourced directly from the elements at a “sky mining facility” in Stroud.

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