Mounjaro is second obesity drug to be approved for use in England

Those with BMI of 35 and a comorbidity can now be prescribed tirzepatide and Nice says it is more effective than Wegovy

The medical treatment regulator for England has approved a second drug to combat obesity, giving patients and doctors what it says is a more effective alternative to semaglutide.

The National Institute for Health and Care Excellence (Nice) issued draft guidance on Tuesday recommending that very obese people should be prescribed tirzepatide, which is marketed in the UK as Mounjaro.

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News outlets producing ‘covert marketing’ for McDonald’s, KFC and Domino’s, study finds

Exclusive: Researchers also say ‘implied endorsement’ raises public health concerns, given poor nutritional quality of the foods

Fast food chains are successfully influencing news outlets to produce “covert marketing” for their brands, a new study has found.

The study, led by the University of Sydney’s School of Public Health, analysed all press releases from McDonald’s, KFC and Domino’s Pizza in Australia between July 2021 and June 2022.

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Artificial cornea implant saves sight of man, 91, in NHS first

Cecil Farley says implant, which could become standard treatment, means he can still see his wife of 63 years

A 91-year-old man who became the first patient in England to have his sight saved by an artificial layer in his cornea has praised the procedure for allowing him to still see his wife.

Cecil Farley, from Chobham in Surrey, had problems with his right eye for about 15 years before losing his vision. He required a cornea transplant to save his sight but his previous surgery – a graft with a human cornea – failed and doctors warned the next might too. And the shortage of human corneas from deceased donors meant Farley faced a year-long wait.

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Women in England and Wales denied ‘exciting’ drug that can stop breast cancer spreading

Latest study shows Enhertu, rejected by Nice, can stall growth of tumours by a year, longer than standard chemotherapy

Thousands of women with advanced breast cancer in England and Wales are being denied a drug that cuts the risk of the disease spreading by more than a third.

Enhertu has been rolled out to patients with HER2-low breast cancer in Scotland and Northern Ireland, but the National Institute for Health and Care Excellence (Nice) has rejected it for patients in England. Women in Wales are also being denied the drug.

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Minority ethnic heart failure patients ‘36% more likely to die’ in UK

Study also finds people from ethnic minorities with atrial fibrillation more than twice as likely to die than white patients

Minority ethnic patients with heart failure are more than a third more likely to die than their white counterparts, according to research.

The study, by researchers at the University of Birmingham and supported by the British Heart Foundation, looked at data from more than 16,700 people from 12 existing clinical trials for heart failure patients.

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Predictive blood test hailed as ‘incredibly exciting’ breast cancer breakthrough

New ‘liquid biopsy’ will act as an early warning sign to anticipate risk of tumours returning

A new blood test can predict the risk of breast cancer returning three years before any tumours show up on scans in an “incredibly exciting” breakthrough that could help more women beat the disease for good.

More than 2 million women are diagnosed every year with breast cancer, the most prevalent type of the disease. Although treatment has improved in recent decades, the cancer often returns, and if it does, it is usually at a more advanced stage.

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Extend success of UK sugar tax to cakes, biscuits and chocolate, experts urge

Exclusive: Co-author of analysis for WHO calls on government to control the food industry rather than being subservient to it

The sugar tax has been so successful in improving people’s diets that it should be extended to cakes, biscuits and chocolate, health experts say.

The World Health Organization wants the next UK government to expand coverage of the levy to help tackle tooth decay, obesity, diabetes and other illnesses.

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Trial results for new lung cancer drug are ‘off the charts’, say doctors

More than half of patients with advanced forms of disease who took lorlatinib were still alive after five years with no progression

Doctors are hailing “off the chart” trial results that show a new drug stopped lung cancer advancing for longer than any other treatment in medical history.

Lung cancer is the world’s leading cause of cancer death, accounting for about 1.8m deaths every year. Survival rates in those with advanced forms of the disease, where tumours have spread, are particularly poor.

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Nigeria to host first Lassa fever treatment trials for 40 years

The viral disease kills 5,000 people a year in west Africa, and has been described as an epidemic threat to global health

Clinical trials for the first new treatment for Lassa fever in almost 40 years are planned to be held in Nigeria this year.

The neglected tropical disease kills about 5,000 people a year and is endemic in west Africa.

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Junior doctors’ strike could delay care for 100,000 NHS patients in England

Rishi Sunak says timing of action days before general election appears to be ‘politically motivated’ to help Labour

Up to 100,000 patients in England face having their NHS care cancelled days before the general election after junior doctors announced a fresh wave of strike action, with Rishi Sunak saying it appeared to be politically motivated.

Health leaders expressed alarm, warning the five-day strike would jeopardise efforts to tackle the record waiting list and “hit patients hard”.

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Labour pledges to clear NHS waiting list backlog in England in five years

Wes Streeting says another Conservative term could result in waiting list swelling to 10m cases

Labour has promised to clear the NHS waiting list backlog in England within five years, with Wes Streeting warning that the health service risks becoming “a poor service for poor people” while the wealthy shift to using private care.

In an interview with the Guardian, the shadow health secretary said that in another Conservative term the total waiting list in England could grow to 10m cases, with healthcare becoming as degraded as NHS dental services.

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Police deploy divers and dog in search for mother and baby after evidence of birth found on Sydney riverbank

Officers urge woman to go to hospital to receive care after placenta and umbilical cord found next to Cooks River at Earlwood

Police have deployed divers and a blood detection dog in the search for a mother and her newborn baby after finding evidence she may have given birth by a Sydney riverbank.

A resident walking his dog found what police believe to be a placenta and umbilical cord next to the Cooks River at Earlwood in the city’s south-west on Monday afternoon. Police said tests on the organs had revealed them to be human.

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How Ozempic is re-shaping the US

The company behind the weight-loss drug has made millions, but without health insurance it is unaffordable for many. George Chidi reports

George Chidi, a politics and democracy reporter for Guardian US, recently came to Europe on holiday. He had been looking forward to eating his way around Paris and London, and was especially looking forward to the cheese. But when he got here, something surprised him. He enjoyed the food but found he wasn’t overeating.

For the past few months, he explains to Hannah Moore, he has been taking the weight-loss drug Ozempic. Almost 2% of the population in the US is taking it and the company behind it is worth billions. But while it’s been a big year for semaglutide weight-loss drugs such as Ozempic, the changes they are making to US society are only just beginning.

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Family infected with parasitic worms in US after eating bear meat, CDC says

Six people who ate a meal in South Dakota in 2022 with black bear meat diagnosed with trichinellosis, a parasitic zoonotic disease

Six people who shared a meal involving black bear meat kebabs have been diagnosed with trichinellosis, a parasitic zoonotic disease.

In a new report released this week, the Centers for Disease Control and Prevention (CDC) revealed that in July 2022, a 29-year old hospitalized patient with suspected trichinellosis was reported to the Minnesota health department. His symptoms included fever, severe muscle aches, periorbital edema or eye swelling, and eosinophilia or the condition of elevated levels of eosinophils, a type of white blood cell.

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NHS England spent £4.1bn over 11 years settling lawsuits over brain-damaged babies

Exclusive: £3.6bn has been paid out in 1,307 cases, according to information obtained under freedom of information laws

The NHS has spent £4.1bn over the last 11 years settling lawsuits involving babies who suffered brain damage when being born, amid claims that maternity units are not learning from mistakes.

It paid out just under £3.6bn in damages in 1,307 cases in which parents were left to care for a baby with cerebral palsy or other forms of brain injury, NHS figures reveal.

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Jarrad Antonovich inquest halted for potential criminal charges over death at NSW spiritual retreat

Coroner suspends inquest into death of man who consumed ayahuasca and frog toxin kambo at the Dreaming Arts festival at Arcoora in 2021

An inquest into the death of a man after taking poison and hallucinogens has been suspended after a coroner found there could be enough evidence for charges to be laid.

Jarrad Antonovich died of a perforated oesophagus after consuming the plant-based psychedelic ayahuasca and frog-based poison kambo at the Dreaming Arts festival at Arcoora retreat in northern NSW on 16 October 2021.

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Huge number of deaths linked to superbugs can be avoided, say experts

Models suggest deaths in poorer countries could be cut by 18% – or about 750,000 a year – with preventive measures

Every year 750,000 deaths linked to drug-resistant superbugs could be prevented through better access to clean water and sanitation, infection control and childhood vaccinations, research suggests.

Antimicrobial resistance, or AMR, is a huge global challenge, with the evolution of drug-resistant superbugs, driven by factors including inappropriate and excessive antibiotic use, raising the prospect of a future where modern medicine fails.

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Texas appoints vocal anti-abortion activist to maternal mortality committee

Dr Ingrid Skop has argued in favor of forcing rape and incest victims as young as nine or 10 to carry pregnancies to term

One of the US’s leading anti-abortion activists has been appointed to a Texas health committee tasked with reviewing maternal deaths.

The move worries reproductive justice advocates who say the state’s abortion ban – among the strictest in the US – has placed pregnant women’s lives in jeopardy. The appointment could undermine the committee’s ability to accurately examine the impact of the law on deaths during and in the immediate aftermath of pregnancy, they say.

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Without measles immunisation ‘little spot fire’ outbreaks may become harder to control, experts warn

People urged to check they are fully immunised after NSW and Victorian health authorities alert to three separate cases of virus in May

Australians are being urged to check they are fully immunised against measles after a number of outbreaks of the highly contagious virus.

Health authorities in New South Wales and Victoria alerted the public in May to three separate cases, all in travellers returning from overseas. There have been 35 confirmed measles cases across Australia so far in 2024, more than in all of 2023.

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Inquest hears claim spiritual leaders conspired to mislead police about Jarrad Antonovich’s death after ‘kambo’ ritual

Antonovich died during a six-day retreat in NSW’s northern rivers after he took a cocktail of alternative ‘medicines’

A group of spiritual leaders at a retreat in the northern rivers conspired to mislead police about the death of a man who had just taken a cocktail of alternative “medicines”, a Bryon Bay courtroom has heard.

The inquest into the death of Jarrad Antonovich also heard that a Brazilian religious tradition fusing Christianity with Amazonian shamanic practices – including the drinking of hallucinogenic tea ayahuasca – gained increasing sway over an Australian community known as the “Church of Ayahuasca” in the lead-up to that fatal ceremony.

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