Vets urged to stop giving pesticide flea treatments after river pollution study

Exclusive: Pet owners risk contaminating their hands with neurotoxins for at least 28 days after application, scientists find

Vets should limit the use of flea treatments containing pesticides on dogs and cats, scientists have said, after a study revealed the vast amount of toxic substances in them that end up in rivers.

Pet owners using these flea treatments risk contaminating their hands with fipronil and imidacloprid, two insecticides, for at least 28 days after the treatment has been applied, according to research by the University of Sussex and Imperial College London.

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Getting fitter can reduce prostate cancer risk by 35%, study finds

Increase in cardiorespiratory levels of 3% annually found to be beneficial, Swedish research suggests

Men can reduce their risk of prostate cancer by as much as 35% by doing a little more jogging, cycling or swimming, a study suggests.

Boosting cardiorespiratory fitness by only 3% over the course of a year was linked to a much lower chance of developing the disease. The findings prompted the researchers to encourage men to boost their fitness levels to help cut their prostate cancer risk.

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World-first blood test for brain cancer may increase survival rates, say experts

Inexpensive test can help diagnose even ‘inaccessible’ tumours earlier, speeding up treatment and improving outcomes

Surgeons and scientists have developed a world-first blood test for brain cancer that experts say could revolutionise diagnosis, speed up treatment and boost survival rates.

For years, brain tumours have remained notoriously difficult to diagnose. They affect hundreds of thousands of people worldwide each year, and kill more children and adults under the age of 40 in the UK than any other cancer.

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Alice is among a growing number of Victorians battling this flesh-eating ulcer. Scientists say they now know why

As Buruli ulcer cases rise in Victoria, Australian researchers say they have finally solved the ‘transmission enigma’

When Alice Mika was bitten by a mosquito last summer in Melbourne’s west, she didn’t think anything of it.

Then, a small raised bump appeared on her ankle more than five months later and wouldn’t go away. She saw her GP who prescribed antibiotics, believing it to be a spider bite.

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Experimental use of pig liver to filter blood externally offers hope for patients

Surgeons at University of Pennsylvania attached modified organ from pig to brain-dead human body

Surgeons externally attached a pig liver to a brain-dead human body and watched it successfully filter blood, a step toward eventually trying the technique in patients with liver failure.

The University of Pennsylvania announced the novel experiment on Thursday, a different spin on animal-to-human organ transplants. In this case, the pig liver was used outside the donated body, not inside – a way to create a “bridge” to support failing livers by doing the organ’s blood-cleansing work externally, much like dialysis for failing kidneys.

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Children living near green spaces ‘have stronger bones’

Bone strength is set in childhood so better park access could prevent fractures in older people, study finds

Children with more green space near their homes have significantly stronger bones, a study has found, potentially leading to lifelong health benefits.

Scientists found that the children living in places with 20-25% more natural areas had increased bone strength that was equivalent to half a year’s natural growth.

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DNA test can detect 18 early stage cancers, scientists say

US biotech firm designs cheaper, less invasive multi-cancer screening test it says could be ‘gamechanger’

Scientists have developed a simple DNA test that can identify 18 early-stage cancers that experts say could represent a medical “gamechanger”.

Cancer accounts for one in every six deaths worldwide, but early detection can significantly improve outcomes. Existing screening tests have drawbacks, including invasiveness, cost and low levels of accuracy for early stage disease.

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Scientists decry wasted opportunity as thousands of frozen eggs languish in IVF storage across Australia

Despite a surplus of eggs at fertility clinics around the country, very few end up being donated to research or other prospective parents

The vast majority of eggs frozen by prospective mothers go unused, causing headaches for IVF clinics and preventing potentially groundbreaking research.

Scientists are decrying a wasted opportunity as thousands of frozen eggs sit unused in storage instead of being used in potentially valuable medical research.

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Scientists call for review of UK’s 14-day rule on embryo research

Extending the limit could help uncover causes of recurrent miscarriage and congenital conditions, experts say

Scientists are calling for a review of the 14-day rule on embryo research, saying that extending the limit could help uncover the causes of recurrent miscarriage and congenital conditions.

Until now, scientists studying the earliest stages of life have been restricted to cultivating embryos up to the equivalent of 14 days of development. They can then pick up the path of development several weeks later, on pregnancy scans and from material donated from terminations.

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AstraZeneca buys Chinese cancer therapy firm Gracell for $1.2bn

Gracell Biotechnologies acquisition marks China’s growing importance to the Anglo-Swedish drugmaker

AstraZeneca has struck a deal to buy a Chinese cancer therapy company for up to $1.2bn (£950m), as Britain’s biggest drugmaker expands its footprint in its second-largest market.

The Anglo-Swedish pharmaceutical firm announced on Tuesday it would acquire Gracell Biotechnologies, which is focused on a type of cancer therapy known as CAR-T that modifies a patient’s cells to fight the disease.

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Comfort eating can impair body’s recovery from stress, study shows

Researchers find turning to fatty and other unhealthy foods for solace reduces vascular function and raises risk of heart disease

Using fatty foods to comfort eat during times of stress can impair the body’s recovery from the pressure, research suggests.

Many people turn to unhealthy foods such as chocolate or crisps when they are feeling the strain, but researchers have found that this can reduce blood flow to the brain and cause poorer vascular function – which in turn can have a negative effect on mental health and cognitive function, and increase the risk of heart disease.

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HIV vaccine trial in Africa halted after disappointing initial results

African-led trial ended a year early as researchers conclude there is ‘little or no chance’ new combination vaccines cut HIV risk

The first trial in Africa of two combination vaccines to prevent HIV has been halted after researchers concluded it was not working.

The vaccines (part of the PrEPVacc study) were being tested on 1,500 people aged between 18 and 40 in Uganda, Tanzania and South Africa.

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Call to help UK IVF patients donate unused embryos after shortage hinders research

Scientists complain after ‘sheer waste’ of human embryos discarded despite patients’ wishes

Leading scientists are calling for a change in the law to help IVF patients donate unused embryos to biomedical research after a collapse in donations over the past 15 years.

The increasing commercialisation of IVF, overstretched NHS clinics and cumbersome paperwork are blamed for a 25-fold decrease in the number of donated embryos. Scientists described some patients going to “extraordinary lengths” to ensure their embryos could be used for research rather than discarded, with many private clinics failing to routinely offer donation as an option.

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Genetic data on 500,000 volunteers in UK to be released for scientific study

UK BioBank offers up biggest ever cache of whole-genome sequences for medical research

A new era of medical discoveries, treatments and cures is on the horizon, researchers say, following the announcement that an unprecedented trove of genetic information is to be made available to scientists.

Health researchers from around the world can now apply to study the whole genomes of half a million people enrolled in UK Biobank, a biomedical research project that has compiled detailed health and lifestyle records on individuals since it began 20 years ago.

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UK Biobank and the masses of medical data that became key to genetic research

The resource, which is on the move to Manchester, now ranks as the world’s most important health database

The origins of the UK Biobank can be traced back to a pilot study in a building in Stockport bordered by the Cheadle Heath police station on one side and the local recreation ground on the other. It was the early 2000s and scientists had realised the potential for genomics and big data to transform health research.

With diabetes, cancer, dementia and other ailments on the rise, scientists pushed for a database devoted to genetics, health and lifestyle to help them tease apart who was most at risk and how diseases could be prevented.

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Bone cows bred in Australia provide base material for dental grafts

Use of cattle from country free of mad cow disease means product is safe, experts say, and patients can still donate blood

Bone cows, specially bred in mad cow-free Australia, are being used instead of human donors for dental and medical bone grafts.

While bovine grafts have been tested for spinal fusion, foot reconstructions and to fix skull traumas, the Australian versions are predominantly used in dental work to strengthen degraded jaws before tooth implants.

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US coal power plants killed at least 460,000 people in past 20 years – report

Pollution caused twice as many premature deaths as previously thought, with updated understanding of dangers of PM2.5

Coal-fired power plants killed at least 460,000 Americans during the past two decades, causing twice as many premature deaths as previously thought, new research has found.

Cars, factories, fire smoke and electricity plants emit tiny toxic air pollutants known as fine particulate matter or PM2.5, which elevate the risk of an array of life-shortening medical conditions including asthma, heart disease, low birth weight and some cancers.

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Cheap over-the-counter nail drug found to work on crippling flesh-eating disease

‘Momentous’ breakthrough as trial finds treatment for nail infections to be highly effective for neglected tropical disease

A cheap and easily taken drug used to treat fungal nail infections has been found to work against a devastating flesh and bone-eating disease found across Africa, Asia and the Americas.

Researchers say the breakthrough offers hope to thousands of patients who have suffered decades of neglect and can face amputations if the disease is left untreated.

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Scientists raise hopes of cure for eczema itchiness with study of skin bacteria

Researchers say they have discovered a common type of bacteria can trigger irritation

Whether it’s a tickle of the nose, or an irritation in one’s hair, itches can be excruciating. Now scientists say they have found a common type of skin bacteria can trigger the sensation.

Crucially, as such bacteria are commonly found on the skin of patients with eczema – or atopic dermatitis – the work helps explain why such conditions can be accompanied by the urge to scratch.

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What we learned from Patrick Vallance at the Covid inquiry

Chief scientific adviser in pandemic says lockdown should have come sooner and that Johnson is not great at science

Sir Patrick Vallance, the UK government’s chief scientific adviser throughout Covid, has been giving evidence to the inquiry into the pandemic on Monday. Here is what we have learned so far.

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