Concerns raised over access to UK Biobank data after ‘race scientists’ claims

Expert says any suggestion of Human Diversity Foundation accessing sensitive data could affect public trust in science

Concerns have been raised about access to a scientific trove containing the genetic data and medical records of more than 500,000 people, after an investigation revealed that “race scientists” appeared to claim to have obtained the data.

A senior scientist has warned that the leadership responsible for the data held by UK Biobank “have to be very careful with ensuring that correct processes are followed” around access to the information in order to maintain public confidence.

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Which disease-modifying Alzheimer’s drugs are the most promising?

Many drugs in development aim to delay, slow or reverse symptoms, but which are causing the biggest stir?

This week England’s health spending watchdog rejected a new Alzheimer’s drug – the second such drug it has turned down this year.

Both donanemab and lecanemab were approved by the UK’s Medicines and Healthcare products Regulatory Agency (MHRA), yet the National Institute for Health and Care Excellence (Nice) said their benefits were too small to justify their costs, while there have also been concerns over potential side-effects – such as brain swelling and bleeding.

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NHS in England to trial AI tool to predict risk of fatal heart disease

‘Superhuman’ technology known as Aire can detect potential problems doctors cannot see from ECG results

The NHS in England is to trial a “superhuman” artificial intelligence tool that predicts a patient’s risk of disease and dying early.

The new technology, known as AI-ECG risk estimation, or Aire, is trained to read the results of electrocardiogram (ECG) tests, which record the electrical activity of the heart and are used to check for problems.

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Rise of almost untreatable superbug linked to a common antibiotic

‘Surprising’ finding by Australian-led study is first recorded instance of one antibiotic causing resistance to another in a different class

The rise of an almost untreatable superbug has been linked to a common antibiotic, an Australian-led study has found.

The study – published in Nature – found that rifaximin, an antibiotic used to treat liver disease, causes resistance to another antibiotic, daptomycin.

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New cervical cancer treatment regime ‘cuts risk of dying from disease by 40%’

Process tested in patients over 10-year period involves short course of chemotherapy before chemoradiation

Doctors are hailing a “remarkable” new treatment regime for cervical cancer that reduces the risk of dying by 40%, in the biggest advance against the disease in 25 years.

Cervical cancer is the fourth most common cancer in women globally, with about 660,000 new cases and 350,000 deaths every year, according to the World Health Organization. In the UK, there are about 3,200 cases and 800 deaths each year.

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Scientists create surgical stitch to aid healing by electrical stimulation

Researchers in China say their suture can speed up wound healing and reduce risk of infection by producing a charge

The humble stitch plays a crucial role in surgery, holding a gash together while tissues repair. Now scientists have created a type of suture they say can help speed up wound healing and reduce the risk of infection.

Researchers in China have created a suture that when put under strain – as occurs during movement – electrically stimulates the wound.

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Severe Covid infections can inflame brain’s ‘control centre’, research says

Scans of people hospitalised with Covid may explain the long-term breathlessness and fatigue some patients experience

Severe Covid infections can drive inflammation in the brain’s “control centre”, researchers say, leading to damage that may explain the long-term breathlessness, fatigue and anxiety some patients experience.

High-resolution MRI scans of 30 people hospitalised with Covid early in the pandemic, before the introduction of vaccines, found signs of inflammation in the brainstem, a small but critical structure that governs life-sustaining bodily functions such as breathing, heart rate and blood pressure.

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Study of new personalised cancer therapies could ‘transform’ how the disease is treated

Large-scale clinical project could give real-time view of how well treatments are working and lead to earlier diagnoses

Scientists are embarking on a large-scale clinical study of new personalised cancer therapies which could give clinicians are real-time view of how well treatments are working.

The £9m partnership between the Francis Crick Institute, five NHS trusts, charities and bioscience companies will spend four years examining the effectiveness of new immunotherapy treatments and exploring new ways to detect cancer.

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Migration during adolescence linked to increased psychosis risk, study finds

Risk found to be highest among black and north African people, as experts call for better mental health provision

People who migrate in adolescence have an increased risk of psychosis, researchers have found, noting the link is particularly strong among black and north African people.

While research has previously suggested migration could play a role in the increased risk of psychosis among people from ethnic minorities, the study suggests age could be an important factor.

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South Sudan medics trial AI app to identify snakes and improve bite treatment

Software with database of 380,000 pictures aims to aid quick and accurate identification and ensure correct use of antivenoms

The race to treat snakebite patients in time to save them could be eased by the development of software powered by artificial intelligence.

The medical charity Médecins Sans Frontières (MSF) is trialling AI snake detection in South Sudan using a database of 380,000 pictures of snakes to identify venomous species.

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Mental health overtakes cancer and obesity as Britons’ biggest health worry

Ipsos survey asked people in 31 countries what they thought of their health and healthcare

Mental health has overtaken cancer and obesity as the health problem most Britons worry about, a global survey has revealed.

Experts said the shift in the public’s perception reflected the sharp rise in recent years in mental ill-health caused by the Covid pandemic, the cost of living crisis and male violence against women.

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Ig Nobel prize goes to team who found mammals can breathe through anuses

Scientific research on pigeon missiles and dead trout also win at awards for amusing studies with serious implications

In a stark demonstration of how award-winning breakthroughs can come from the most unlikely directions, researchers have won an Ig Nobel prize for discovering that mammals can breathe through their anuses.

After a series of tests on mice, rats and pigs, Japanese scientists found the animals absorb oxygen delivered through the rectum, work that underpins a clinical trial to see whether the procedure can treat respiratory failure.

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Pathogenic microbes blown vast distances by winds, scientists discover

Living microbes that cause disease in humans and host antibiotic-resistance genes carried 1,200 miles

Microbes that cause disease in humans can travel thousands of miles on high-level winds, scientists have revealed for the first time.

The winds studied carried a surprising diversity of bacteria and fungi, including known pathogens and, some with genes for resistance to multiple antibiotics. Some of the microbes were shown to be alive – in other words, they had survived the long journey and were able to replicate.

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Africa to finally receive first batch of vaccines for deadly mpox virus

The continent will belatedly get 10,000 shots amid criticism of delays to the process caused by WHO red tape

Africa’s first batch of mpox vaccines will this week finally reach the continent, weeks after they have been made available in other parts of the world.

The 10,000 shots, donated by the US, will be used to tackle a dangerous new variant of the virus, formerly known as monkeypox, after a 2022 outbreak triggered global alarm.

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‘Real hope’ for cystic fibrosis patients as NHS rolls out life-changing drug

Campaigners hail decision to give thousands of sufferers access to new set of drugs known as ‘modulators’

Alix Oxlade was 30 weeks into her pregnancy when scans showed fluid building up in the stomach and bowels of her unborn son, Rufus. The cause was unclear, though there was an early suspect: cystic fibrosis.

One of the most common inherited illnesses in the west, cystic fibrosis is caused by a defective protein that allows mucus to build up in the lungs, bowels and other organs and can lead to chronic infections that worsen through life. Tests subsequently showed Alix and her partner, Ben, who live in East Yorkshire, were both carriers of the disease.

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Mpox outbreak in Africa is public health emergency, declares WHO

Outbreak resembles early days of HIV, say experts, urging accelerated access to vaccines and testing

An outbreak in Africa of mpox, the disease formerly known as monkeypox, resembles the early days of HIV, scientists have said, as the World Health Organization declared it a public health emergency.

The declaration must accelerate access to testing, vaccines and therapeutic drugs in the affected areas, medical experts urged, and kickstart campaigns to reduce stigma surrounding the virus.

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Cannabis could help people cut down or stop opioid use, research shows

USC study finds cannabis can help manage withdrawal symptoms, as well as cravings and anxiety after withdrawal

New research from the University of Southern California shows that cannabis might help some people stop or cut down on their opioid use.

“We interviewed 30 people who were using opioids and cannabis and injecting drugs,” said Sid Ganesh, a PhD student at USC’s medical school and lead author of the study.

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Bereavement in early life may accelerate ageing, research shows

Separate study shows poor diet and added sugar also linked to rise in biological age

The stress of bereavement may accelerate the ageing process, according to researchers who found evidence that losing a loved one early in life had an impact long before people reach middle age.

Scientists spotted biological markers of faster ageing in people who had lost a parent, partner, sibling or child, but the signs were absent in others who had not experienced the death of someone close to them.

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Doctor behind trial of HIV prevention drug recounts breakthrough moment

Prof Linda-Gail Bekker receives ovation at Aids summit after presenting trial results of ‘miracle’ drug lenacapavir

When the doctor behind the trial of a new HIV prevention drug heard the results, she could not contain her emotions. “I literally burst into tears,” said Prof Linda-Gail Bekker.

“I’m 62, I’ve lived through this epidemic … I had family members who died of HIV, as did many, many Africans – many people around the world,” she said.

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Childhood air pollution directly linked to adult lung health, study says

Connection found between early exposure and bronchitic symptoms in adults without previous lung problems

Air pollution breathed in during childhood is one of the factors in adult lung health, according to a new study.

The origins of the study date back to 1992 when researchers began investigating the effects of air pollution on groups of children in California. Some of these children are now in their 40s.

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