‘He drives me mad!’ Why don’t we dump toxic friends?

According to psychologists, ‘ambivalent’ relationships can cause us more stress than being with people we actively dislike. Is it time to let go – or can these friendships be salvaged?

Roger and Jim have been friends for more than 30 years. When they were younger they were in a band together, and their friendship was forged over a shared love of music and beer. Even now, despite family commitments on both sides, they manage to catch up every couple of months. “Even though he drives me mad,” says Roger.

It is Jim who leaps to Roger’s mind at the mention of toxic friendships. Every time they meet, Roger says, they “tend to have the same conversation”, because Jim never listens to what he says.

Continue reading...

California women gave birth to each other’s babies after IVF mix-up

Couples to sue clinic after raising girls for months that were not theirs, says lawsuit, before babies were swapped back

Two California couples gave birth to each other’s babies after a mix-up at a fertility clinic and spent months raising children that were not theirs before swapping the infants, according to a lawsuit filed in Los Angeles.

Daphna Cardinale said she and her husband, Alexander, had immediate suspicions that the girl she gave birth to in late 2019 was not theirs due to the child’s darker complexion.

Continue reading...

Nigeria unlikely to reach ‘impossible’ 40% Covid vaccine target

Lack of doses and a reluctant public make government programme unfeasible, say health experts, with malaria and conflict posing greater risk to life

It will be “impossible” for Nigeria to meet its target of vaccinating 40% of its population by the end of the year because Covid is not being taken seriously, health experts have warned.

Fewer than 1.5% of the country’s 206 million population has been fully vaccinated. But with more people killed in conflict last year and substantially more recorded deaths from malaria than Covid in Nigeria, experts believe it is further down the list of concerns for many in the country.

Continue reading...

Australia news live update: WA nurse charged over alleged Covid vaccine fraud; booster shots available from today; more freedoms for NSW

Nurse accused of faking a Covid vaccination; Adem Somyurek appears before Ibac; Victoria records 1,126 cases and five deaths; NSW reports 187 cases, seven deaths; ACT has 13 new cases; Barnaby Joyce slams ex-PMs’ criticisms of PM; vaccine boosters roll out; NSW scraps home-visit limits for vaccinated. Follow the day’s news

Health minister Greg Hunt is also on the interview circuit this morning and has been asked if booster shots will be required for people to keep the freedoms given to those who have been double vaccinated:

Not at this stage. it is not our medical advice. What a booster is, is exactly as the name says. It adds to your vaccination. It boosts your vaccination. It boosts your vaccination and protection.

We are opening up today across the country to anyone who is six months or more from their vaccination.

Continue reading...

‘Get the vaccine’: family of Covid victim’s plea to pregnant women

Saiqa Parveen planned to have jab after giving birth but died from disease after daughter was delivered by emergency caesarean

She was eight months pregnant and weeks from welcoming her fifth daughter to the world, but Saiqa Parveen died of Covid after putting off getting the coronavirus jab. Her family have now issued an emotional plea for pregnant women to get vaccinated.

Parveen, 37, had planned to delay having the jab until her baby was born, her family said, but she was admitted to hospital with breathing difficulties in September and put on a ventilator.

Continue reading...

Will the magic of psychedelics transform psychiatry?

Psychedelics have come a long way since their hallucinogenic hippy heyday. Research shows that they could alleviate PTSD, depression and addiction. So will we all soon be treated with magic mushrooms and MDMA?

Imagine a medicine that could help people process disturbing memories, sparking behavioural changes rather than merely burying and suppressing symptoms and trauma. For the millions suffering with post-traumatic stress disorder (PTSD) and depression, such remedies for their daily struggles could be on the horizon. Psychiatry is rapidly heading towards a new frontier – and it’s all thanks to psychedelics.

In an advanced phase trial published in Nature in May, patients in the US, Israel and Canada who received doses of the psychedelic stimulant MDMA, alongside care from a therapist, were more than twice as likely than the placebo group to no longer have PTSD, for which there is currently no effective treatment, months later. The researchers concluded that the findings, which reflected those of six earlier-stage trials, cemented the treatment as a startlingly successful potential breakthrough therapy. There are now hopes that MDMA therapy could receive approval for certain treatments from US regulators by 2023, or perhaps even earlier – with psilocybin, the active ingredient of magic mushrooms, not far behind in the process. (A small study at Johns Hopkins University, published last year, suggested it could be four times more effective than traditional antidepressants.)

Continue reading...

Coronavirus live: Russia cases hit record daily high, England speeds up booster jab rollout

People in England will be able to book their Covid-19 booster jab a month before they are eligible from Monday

Two hyenas at the US Denver zoo have tested positive for Covid-19, the first confirmed cases among the animals worldwide.

Samples from a variety of animals at the zoo, including the spotted hyenas, were tested after several of its lions became ill, according to the National Veterinary Services Laboratories (NVSL). The hyena samples tested presumptive positive at a lab at Colorado State University and were confirmed by the national lab.

Continue reading...

Australia news live updates: NT to decide if Covid lockdown extended, Tim Smith won’t contest Victoria election after drunken crash

Katherine stay-at-home restrictions due to lift at midnight, but source of outbreak still not known. Follow updates live

Labor will create a national anti-scam centre and double funding for services helping aggrieved Australians get stolen IDs back to counter scammers if it wins government, AAP reports.

Forcing companies to take down fraudulent ads faster, a review of the current penalties in place for scammers and a new ministerial portfolio for the issue will be introduced under its “scambuster” plan.

Continue reading...

Cranberry juice won’t cut it: UTIs and the potential for repurposing drugs

The winning essay in the Max Perutz science writing award 2021, published below, was written by Vicky Bennett from the department of biology and biochemistry at Bath University

In May, PhD students who are funded by the Medical Research Council (MRC) were invited to enter the Max Perutz science writing award 2021 and write a compelling piece about their research for the non-scientific reader.

From the many entries received, the 10 that made the shortlist covered diverse topics, including dementia, childhood adversity, the role of genes in schizophrenia and the use of hypnosis to treat psychosis.

Continue reading...

Welsh study shows impact of Covid on 10- and 11-year-olds

Children ate less healthily, took less exercise and had more emotional problems, say researchers

Children in the UK ate fewer vegetables, took less exercise and experienced worsening emotional difficulties following the Covid outbreak, according to a research study.

A biennial survey conducted by investigators at Cardiff University found that primary school-age children reported a sharp increase in “elevated or clinically significant emotional difficulties” in early 2021, compared with the same survey conducted in 2019.

Continue reading...

Europe once again at centre of Covid pandemic, says WHO

Cases at near-record levels and 500,000 more deaths forecast by February

Uneven vaccine coverage and a relaxation of preventive measures have brought Europe to a “critical point” in the pandemic, the World Health Organization has said, with cases again at near-record levels and 500,000 more deaths forecast by February.

Hans Kluge, the WHO’s Europe director, said all 53 countries in the region were facing “a real threat of Covid-19 resurgence or already fighting it” and urged governments to reimpose or continue with social and public health measures.

Continue reading...

UK is first to approve oral antiviral pill to treat Covid

Pill can be taken twice daily at home and priority will be given to elderly patients and those with health vulnerabilities

The UK medicines regulator has become the first in the world to approve an oral antiviral pill for Covid in a move that paves the way for tens of thousands of vulnerable patients to receive the treatment from this winter.

Nearly half a million doses of molnupiravir, a pill that can be taken twice daily at home, are due for delivery from mid-November and will be given as a priority to elderly Covid patients and those with particular vulnerabilities, such as weakened immune systems. The drug will initially be given to patients through a national study run by the NHS.

Continue reading...

‘It gave me an ability to enjoy life’: readers on cognitive behavioural therapy

Two people tell us about their experiences with CBT and how it changed their lives

The psychotherapist Aaron Beck, known as the father of cognitive behavioural therapy (CBT), died on Tuesday aged 100 at his Philadelphia home. CBT is a form of treatment that helps patients to analyse and manage negative thinking patterns rather than focusing on past conflicts. Here, two people tell us about their experiences with CBT and how it changed their lives.

Continue reading...

‘It is what girls need’: the FGM activist hoping to be the Gambia’s president

Despite inexperience and few allies, Jaha Dukureh is offering people change and a break with the past in December’s election

Jaha Dukureh was a young mother of three with little campaigning experience when she started a movement in the Gambia to end female genital mutilation, backed by the Guardian.

In the seven years that followed she advised Barack Obama in the US, where she was then living, helped have FGM banned in her home country, was nominated for a Nobel peace prize and became a UN ambassador.

Continue reading...

Vaccine certificates-for-sale scam undermines Lesotho’s Covid effort

The documents, necessary for entry into bars and sporting venues, are being sold by unscrupulous health workers for less than £20

The Lesotho government’s plans to implement a Covid passport system this week are being undermined by widespread fraud involving certificates being sold to unvaccinated people.

Covid-19 vaccination certificates are being sold for less than £20 by unscrupulous health workers to the largely vaccine-averse population in Lesotho, where there has been little positive campaigning around the jabs.

Continue reading...

‘He was adamant he didn’t want it’: the pro-vax parents with vaccine-hesitant kids

Among under-18s, vaccine uptake is low, and there is a growing issue with misinformation spread on social media and at school. Is there anything a concerned caregiver can do?

Throughout the pandemic, Anna has worked for the NHS. She has seen the effects of Covid-19 first-hand and, although she worked remotely because she was in a vulnerable group, other colleagues – she is a physiotherapist – were deployed to Covid wards at the height of hospital admissions. “At the trust I work for, they’re setting up a long-Covid service,” she says. She comes home and her son Sam, 16, listens to her talk about it – and yet he is adamant that the coronavirus isn’t happening or that, if it is, it’s not serious. “You know: ‘Covid is a load of rubbish – it’s all about control’,” she says. “It’s all very conspiracy theory, a lot of his stuff.” He was adamant from the start that he wouldn’t be having the vaccine if and when it became available for his age group, and he has stuck to it. “He is very resistant,” says Anna. “He is pretty determined not to conform anyway. Part of it, I think, is him being a teenager, and the other bit of it is conspiracy theory: ‘It’s all a big con.’” His main source of information since the start of the pandemic has been social media, says Anna. “He watches a lot of YouTube.”

Just over a month ago, YouTube announced it would remove videos that spread misinformation about all vaccines, and would ban the accounts of anti-vax activists; it had already banned content with false claims about Covid vaccines last year. Facebook did the same in February this year, though a quick search reveals misinformation is still easy to find (one post I found within minutes claimed 80% of vaccinated women had miscarriages). On TikTok, “unvaxxed” content racks up hundreds of thousands of views. Last month, NewsGuard, an organisation that rates the credibility of news organisations and monitors misinformation, found Covid conspiracy theories were being viewed by millions on TikTok, and, in its research, children under 13 – the lower age limit – were able to access the app.

Continue reading...

Bill Gates call for huge global effort to prepare for future pandemics

Microsoft founder says research and development budgets should focus on weaknesses exposed by rapid spread of Covid

A global research effort worth tens of billions of dollars is needed to ensure the world is better prepared for the next pandemic, which could be far worse than Covid, Bill Gates has said.

The Microsoft founder said the “completely horrific” death toll and economic damage inflicted by coronavirus should drive funding into projects aimed at improving vaccines, treatments and diagnostic tests that will be needed to contain the next pandemic more effectively.

Continue reading...

No 10 concerned as 4.5 million eligible people fail to get Covid jab boosters

Downing Street fear hospitalisations and deaths among double-vaccinated could rise due to waning immunity

No 10 is increasingly worried that hospitalisations and deaths among double-vaccinated people could rise due to waning immunity as an estimated 4.5 million people have failed to get their booster shots despite being eligible.

Downing Street sources told the Guardian that the gap between those eligible and those jabbed was too wide, ranking it as their major concern ahead of the winter months.

Continue reading...

Australians fired for refusing Covid vaccine search social media for ‘welcoming’ employers

People turn to Telegram and Facebook to find jobs as mandates bite

Unvaccinated Australians who have lost their jobs for refusing to comply with Covid vaccine mandates are using social media to find and share employment opportunities at workplaces where the new rules are not being enforced.

Telegram and Facebook have had an influx of people searching for paid jobs after states and territories implemented mandates covering a range of industries from health and aged care workers, teachers and police to construction and hospitality workers.

Sign up to receive an email with the top stories from Guardian Australia every morning

Continue reading...

Nearly two-thirds of those who died young in 2019 were male, research finds

Boys and young men neglected in efforts to tackle mortality in 10- to 24-year-olds, Lancet report says, with a failure to address violence, substance use and accidents

Boys and men are more likely than women to die as teenagers or young adults, according to new research that warns the gender gap in mortality rates for that age group is widening in many countries.

In 2019, boys and young men aged 10 to 24 accounted for nearly two-thirds (61%) of all global deaths.

Continue reading...