Oprah Conducts Farewell Interview With First Lady Michelle Obama Oprah Winfrey, back to doing what she does best, sat down with First Lady Michelle Obama to talk about her final weeks in The White House. In the special, Oprah joins FLOTUS for her final one-on-one interview inside the First Family’s residence to talk about life at 1600 Pennsylvania Avenue, her eight years as First Lady of the United States, the legacy she leaves behind, and what’s in store for the future.