Patton Oswalt’s wife Michelle McNamara died suddenly from a combination of prescription drugs and undiagnosed heart condition, comedian says Oswalt, who has a seven-year-old daughter with her, said her death ‘hasn’t left a void, she’s left a blast crater’ Patton Oswalt’s wife Michelle McNamara’s sudden death last year stemmed from a combination of prescription medications and an undiagnosed heart condition, the comedian said Friday. Oswalt released a statement saying coroner’s officials had informed him of his wife’s cause of death.